hmmpfam - search a single seq against HMM database HMMER 2.1.1 (Dec 1998) Copyright (C) 1992-1998 Washington University School of Medicine HMMER is freely distributed under the GNU General Public License (GPL). - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /data11/genetics/InterProScan/iprscan/data/smart.HMMs Sequence file: /cdna4/rodent/full/goal/mpg/mpg00286/w3open/interpro/cnk_1/seq.in - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: mKIAA1139 ( 1224 res) mpg00286 Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- ANK ankyrin repeats 159.3 3.9e-43 7 SAM Sterile alpha motif. 111.6 9.1e-29 2 SH3 Src homology 3 domains 37.4 1.9e-06 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- ANK 1/7 25 55 .. 1 30 [] 2.4 2.2e+03 ANK 2/7 71 100 .. 1 30 [] 29.3 0.00052 ANK 3/7 104 133 .. 1 30 [] 25.8 0.006 ANK 4/7 137 166 .. 1 30 [] 30.4 0.00025 ANK 5/7 170 199 .. 1 30 [] 15.9 5.6 ANK 6/7 211 240 .. 1 30 [] 35.8 5.9e-06 ANK 7/7 243 272 .. 1 30 [] 25.3 0.0085 SH3 1/1 307 369 .. 1 58 [] 37.4 1.9e-06 SAM 1/2 508 574 .. 1 67 [] 54.5 1.4e-11 SAM 2/2 577 644 .. 1 67 [] 57.1 2.3e-12 Alignments of top-scoring domains: ANK: domain 1 of 7, from 25 to 55: score 2.4, E = 2.2e+03 *->dGrTpLHlAaengnlevvklLldkga.dina<-* L lA++ng++ +v+ L+ k ++ mKIAA1139 25 GREQDLILAVKNGDVTCVQKLVAKVKaAKTK 55 ANK: domain 2 of 7, from 71 to 100: score 29.3, E = 0.00052 *->dGrTpLHlAaengnlevvklLldkgadina<-* dG+++LH+Aa g+le++ lLl++ a++++ mKIAA1139 71 DGFSALHHAALGGSLELIALLLEAQATVDI 100 ANK: domain 3 of 7, from 104 to 133: score 25.8, E = 0.006 *->dGrTpLHlAaengnlevvklLldkgadina<-* +G+ pLH+Aa g+le v+lLl+++a +na mKIAA1139 104 NGMRPLHYAAWQGRLEPVRLLLRASAAVNA 133 ANK: domain 4 of 7, from 137 to 166: score 30.4, E = 0.00025 *->dGrTpLHlAaengnlevvklLldkgadina<-* dG+ pLHlAa++g++ev ++Ll++ ++ + mKIAA1139 137 DGQIPLHLAAQYGHYEVSEMLLQHQSNPCL 166 ANK: domain 5 of 7, from 170 to 199: score 15.9, E = 5.6 *->dGrTpLHlAaengnlevvklLldkgadina<-* +TpL lA+e g+l+v++lLl++ + + mKIAA1139 170 LKKTPLDLACEFGRLKVAQLLLNSHLCVAL 199 ANK: domain 6 of 7, from 211 to 240: score 35.8, E = 5.9e-06 *->dGrTpLHlAaengnlevvklLldkgadina<-* + TpLHlAa+ng+ ev++ Ll++g +in mKIAA1139 211 NYTTPLHLAAKNGHREVIRQLLKAGIEINR 240 ANK: domain 7 of 7, from 243 to 272: score 25.3, E = 0.0085 *->dGrTpLHlAaengnlevvklLldkgadina<-* T+LH Aa +g evv+lLl+ g+d+n+ mKIAA1139 243 KTGTALHEAALYGKTEVVRLLLEGGVDVNI 272 SH3: domain 1 of 1, from 307 to 369: score 37.4, E = 1.9e-06 *->eyvvAlYDyea.qnedELsFkkGDiitvleksddgWweGelnr.... +v+Al D+ ++ L +++GD+itvle++ dg w+G ++ ++++ mKIAA1139 307 LKVRALKDFWNlHDPTALNVRAGDVITVLEQHPDGRWKGHIHEsqrg 353 tGkeGlfPsnYVeeie<-* t ++G+fP Ve++ mKIAA1139 354 TDRVGYFPPGIVEVVS 369 SAM: domain 1 of 2, from 508 to 574: score 54.5, E = 1.4e-11 *->vs.wspesVaeWLesigleqYadnFrkngidgeelllltseedLkel ++ + + +WL +le Y+ +F+++g+d ++t edL+ + mKIAA1139 508 LEgKDAQAIHNWLSEFQLEGYTAHFLQAGYDVPTISRMT-PEDLTAI 553 GitllGhRkkIlsaiqklkeq<-* G+t++GhRkkI+s+i +l mKIAA1139 554 GVTKPGHRKKIASEIAQLSIA 574 SAM: domain 2 of 2, from 577 to 644: score 57.1, E = 2.3e-12 *->vs.wspesVaeWLesigleqYadnFrkngidgeelllltseedLkel ++ p ++ eWL ++gl+qY +++ + g+d++ l++ ++ e L+e+ mKIAA1139 577 LPnYIPVDLLEWLCALGLPQYHKQLVSSGYDSMGLVADLTWEELQEI 623 GitllGhRkkIlsaiqklkeq<-* G+++lGh+kk++ +++ l e mKIAA1139 624 GVNKLGHQKKLMLGVKRLAEL 644 [output cut off at A = 10 top alignments] //