hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpg/mpg00286/w3open/interpro/cnk_1/seq.in
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query:  mKIAA1139  ( 1224 res)   mpg00286

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
Ank      Ankyrin repeat                                 168.3    1.3e-46   6
SAM_1    SAM domain (Sterile alpha motif)               164.9    1.4e-45   2
SAM_2    SAM domain (Sterile alpha motif)               100.0    4.7e-26   2
SH3_2    Variant SH3 domain                              26.7    0.00052   1
SH3_1    SH3 domain                                      17.5     0.0026   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Ank        1/6      71   103 ..     1    33 []    35.8  9.7e-07
Ank        2/6     104   136 ..     1    33 []    28.5  0.00015
Ank        3/6     137   169 ..     1    33 []    38.4  1.6e-07
Ank        4/6     170   202 ..     1    33 []     8.2       13
Ank        5/6     211   243 ..     1    33 []    40.4  3.9e-08
Ank        6/6     246   275 ..     1    33 []    26.2  0.00076
SH3_1      1/1     307   368 ..     1    58 []    17.5   0.0026
SH3_2      1/1     308   368 ..     1    69 []    26.7  0.00052
SAM_1      1/2     509   572 ..     1    66 []    84.1  2.8e-21
SAM_2      1/2     508   574 ..     1    72 []    52.3    1e-11
SAM_1      2/2     578   642 ..     1    66 []    80.7    3e-20
SAM_2      2/2     578   644 ..     1    72 []    47.6  2.8e-10

Alignments of top-scoring domains:
Ank: domain 1 of 6, from 71 to 103: score 35.8, E = 9.7e-07
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                      dGf++LH+Aal g+le++ lLl++ A ++++d    
   mKIAA1139    71    DGFSALHHAALGGSLELIALLLEAQATVDIKDS    103  

Ank: domain 2 of 6, from 104 to 136: score 28.5, E = 0.00015
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                      +G+ PLH+Aa  g+le v+lLl + A +na      
   mKIAA1139   104    NGMRPLHYAAWQGRLEPVRLLLRASAAVNAASL    136  

Ank: domain 3 of 6, from 137 to 169: score 38.4, E = 1.6e-07
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                      dG+ PLHlAa++g++ev ++Ll++  +++++++   
   mKIAA1139   137    DGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNK    169  

Ank: domain 4 of 6, from 170 to 202: score 8.2, E = 13
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                         TPL lA++ g+l+v++lLl+   ++ +      
   mKIAA1139   170    LKKTPLDLACEFGRLKVAQLLLNSHLCVALLEG    202  

Ank: domain 5 of 6, from 211 to 243: score 40.4, E = 3.9e-08
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                      +  TPLHlAa++g+ ev++ Ll++G ++n q++   
   mKIAA1139   211    NYTTPLHLAAKNGHREVIRQLLKAGIEINRQTK    243  

Ank: domain 6 of 6, from 246 to 275: score 26.2, E = 0.00076
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                         T+LH Aal+g +evv+lLl+ G d+n+++    
   mKIAA1139   246    ---TALHEAALYGKTEVVRLLLEGGVDVNIRNT    275  

SH3_1: domain 1 of 1, from 307 to 368: score 17.5, E = 0.0026
                   *->kkvvALYDYeare.sdELsFkkGDvitvleksddgWWkgrlkgtgG.
                       kv+AL D+   +++  L  + GDvitvle+++dg Wkg  + +  +
   mKIAA1139   307    LKVRALKDFWNLHdPTALNVRAGDVITVLEQHPDGRWKGHIHESQRg 353  

                   ..keGliPsNYVepv<-*
                   ++++G++P   Ve v   
   mKIAA1139   354 tdRVGYFPPGIVEVV    368  

SH3_2: domain 1 of 1, from 308 to 368: score 26.7, E = 0.00052
                   *->ygraiedyvaAt.dknenleeeeLslkkGdvvkvidv.ggskdddgw
                      ++ra++d+ +  +d+++      L++++Gdv+ v+ ++ ++ ++ g+
   mKIAA1139   308    KVRALKDFWN-LhDPTA------LNVRAGDVITVL-EqHPDGRWKGH 346  

                   .wlgeslggGrrrRGlvPssaveel<-*
                     +  + g  r+  G++P+ +ve++   
   mKIAA1139   347 iHESQR-GTDRV--GYFPPGIVEVV    368  

SAM_1: domain 1 of 2, from 509 to 572: score 84.1, E = 2.8e-21
                   *->dgwsvesVgeWLesigllgqYidnFlaagyidgdtllqlteeDLedl
                      +g++ + + +WL ++ l + Y+ +Fl+agy d++t+ ++t+eDL+++
   mKIAA1139   509    EGKDAQAIHNWLSEFQL-EGYTAHFLQAGY-DVPTISRMTPEDLTAI 553  

                   GvtllGHrkkIlssIqgLk<-*
                   Gvt++GHrkkI+s I +L    
   mKIAA1139   554 GVTKPGHRKKIASEIAQLS    572  

SAM_2: domain 1 of 2, from 508 to 574: score 52.3, E = 1e-11
                   *->veswslesvaeWLesiglegqYkdnFsdqgitglellllrlteedLa
                       e ++++ +++WL++  l + Y+  F+++g++    +  r+t edL 
   mKIAA1139   508    LEGKDAQAIHNWLSEFQL-EGYTAHFLQAGYDV-PTI-SRMTPEDL- 550  

                   klalGitsvghRkkilskiqelkqq<-*
                   + a+G+t++ghRkki s+i +l      
   mKIAA1139   551 T-AIGVTKPGHRKKIASEIAQLSIA    574  

SAM_1: domain 2 of 2, from 578 to 642: score 80.7, E = 3e-20
                   *->dgwsvesVgeWLesigllgqYidnFlaagyidgdtllqlteeDLedl
                      ++  + ++ eWL ++gl +qY ++ ++ gy+++ +++ lt+e+L+++
   mKIAA1139   578    PNYIPVDLLEWLCALGL-PQYHKQLVSSGYDSMGLVADLTWEELQEI 623  

                   GvtllGHrkkIlssIqgLk<-*
                   Gv++lGH+kk+++++++L    
   mKIAA1139   624 GVNKLGHQKKLMLGVKRLA    642  

SAM_2: domain 2 of 2, from 578 to 644: score 47.6, E = 2.8e-10
                   *->veswslesvaeWLesiglegqYkdnFsdqgitglellllrlteedLa
                      + +  + ++ eWL ++gl +qY   + + g++++ l+ + lt e+L 
   mKIAA1139   578    PNYIPV-DLLEWLCALGL-PQYHKQLVSSGYDSMGLV-ADLTWEEL- 620  

                   klalGitsvghRkkilskiqelkqq<-*
                   + ++G++++gh+kk++ ++++l +    
   mKIAA1139   621 Q-EIGVNKLGHQKKLMLGVKRLAEL    644  

//