hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj36158/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1124  ( 1086 res)   mfj36158

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
CNH      CNH domain                                     344.2    1.4e-99   1
C1_1     Phorbol esters/diacylglycerol binding domain    62.5    8.8e-15   1
PH       PH domain                                       29.3    8.9e-05   1
M        M protein repeat                                21.5       0.02   3
PBD      P21-Rho-binding domain                          15.7      0.029   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
M          1/3     144   164 ..     1    21 []    11.0       29
M          2/3     165   185 ..     1    21 []    13.9      3.8
M          3/3     282   302 ..     1    21 []     6.7  1.1e+02
C1_1       1/1     400   452 ..     1    55 []    62.5  8.8e-15
PH         1/1     470   588 ..     1    92 []    29.3  8.9e-05
CNH        1/1     615   888 ..     1   363 []   344.2  1.4e-99
PBD        1/1     957  1008 ..     1    60 []    15.7    0.029

Alignments of top-scoring domains:
M: domain 1 of 3, from 144 to 164: score 11.0, E = 29
                   *->eaKKeLEaelqeLeeelqkLe<-*
                      +++K+L+ae+ +L    +kL+   
   mKIAA1124   144    DENKKLTAENEKLCSFVDKLT    164  

M: domain 2 of 3, from 165 to 185: score 13.9, E = 3.8
                   *->eaKKeLEaelqeLeeelqkLe<-*
                      +++++LE elq+L  +++ +    
   mKIAA1124   165    AQNRQLEDELQDLASKKESVA    185  

M: domain 3 of 3, from 282 to 302: score 6.7, E = 1.1e+02
                   *->eaKKeLEaelqeLeeelqkLe<-*
                      ++ Ke Ea++ eL ee q L    
   mKIAA1124   282    SKLKESEAKNRELLEEMQSLR    302  

C1_1: domain 1 of 1, from 400 to 452: score 62.5, E = 8.8e-15
                   *->HhFvhrwnfkqptfCdhCgellwgslgkqGlkCswCklnvHkrChek
                      H+F  + +f++pt C+hC +l+ g l++qG+ C++C + +H  C   
   mKIAA1124   400    HQFSIK-SFPSPTQCSHCTSLMVG-LIRQGYACEVCAFSCHVSCKDS 444  

                   VppeCgcg<-*
                   +p  C+     
   mKIAA1124   445 APQVCPIP    452  

PH: domain 1 of 1, from 470 to 588: score 29.3, E = 8.9e-05
                   *->vikeGwLlkkg...gkkswkkRyfvLfndvLlyykdkk.......kk
                        ++G++++  +++ kk+w++ y+v+++  L++y+ + +++++++  
   mKIAA1124   470    TAYKGYVKVPKptgVKKGWQRAYAVVCDCKLFLYDLPEgkstqpgVV 516  

                   pkgsipLsgiqvekvpdn..........krkncFeirt.dr......etl
                      +++L++ ++   +   ++  + ++++ ++ F+++ +  ++++++ +l
   mKIAA1124   517 ASQVLDLRDEEFAVSSVLasdvihatrrDIPCIFRVTAsLLgspsktSSL 566  

                   llqaeseeerkeWvkaiqsair<-*
                   l+ +e+e e+++Wv  ++ +++   
   mKIAA1124   567 LILTENENEKRKWVGILEGLQA    588  

CNH: domain 1 of 1, from 615 to 888: score 344.2, E = 1.4e-99
                   *->kvnwihaitggqnLLvGTeeGLYvlnrsdqhdaflgklvkiigrrsv
                      k+ +++ai +g++++vG eeGLYv++++++       +v+++++++v
   mKIAA1124   615    KAVLAAAIVDGDRIAVGLEEGLYVIELTRD------VIVRAADCKKV 655  

                   tqlevieelnlLllLseGKkrhLylhpLsaLetekkdtaqgsskinklpe
                    q+e+ +++++ +lL+ G+++h++l+p+s+                    
   mKIAA1124   656 YQIELAPKEKIAILLC-GRNHHVHLYPWSSF------------------- 685  

                   ktlarrfavskKipetkghCklccvgfiregycggtkFlcvvAlksddls
                     +a  + +++K+petkg C+l+++g+ r++ +++++F   vA+k+    
   mKIAA1124   686 -DGAEASNFDIKLPETKG-CQLIATGTLRKS-SSTCLF---VAVKR---- 725  

                   tsillyeWPlkeyklpnnyekllkfinrkktrfrkpkeldvpepvqsief
                     il+ye                  i+r+k+++rk++el+ p++vq++++
   mKIAA1124   726 -LILCYE------------------IQRTKPFHRKFSELVAPGHVQWMAV 756  

                   lkpslcvGcskgfeillvlfgssgfhslsleGqseaaldlllPsndlsle
                   +k++lcvG+++gf  l++++             ++  ldl++P ++ sl+
   mKIAA1124   757 FKDRLCVGYPSGFSLLSIQG-------------DGPPLDLVNPTDP-SLA 792  

                   fakkls.QsvdalrakevvsaiqidrdeyLLCfsefgvfVNlqGrrsrkk
                   f   ls+Qs+dal+a+e+      +++eyLLCfs++g++V++qGrrsr +
   mKIAA1124   793 F---LSqQSFDALCAVEL------KSEEYLLCFSHMGLYVDPQGRRSRMQ 833  

                   kdiselmWegaPesfayslypyllafhdngieIrsletgeltqeladrvq
                       elmW++aP ++ +s + ++++++++g+++++++t+e+       vq
   mKIAA1124   834 ----ELMWPAAPVACSCS-PTHVTVYSEYGVDVFDVRTMEW-------VQ 871  

                   tillnkirllvslrsls<-*
                   ti+l++ir+l+s++sl+   
   mKIAA1124   872 TIGLRRIRPLNSDGSLN    888  

PBD: domain 1 of 1, from 957 to 1008: score 15.7, E = 0.029
                   *->eIStPLtnFkHvvHVGfDgdtGfftGlPpeWekllkssgiskpeqkk
                      +IS+P tnF Hv+H G       +  lP + +  ++         k+
   mKIAA1124   957    MISNP-TNFNHVAHMGPGDGMQVLMDLPLSAAPTVQEE-------KQ 995  

                   npqavldvlkfys<-*
                    p+ +    +++s   
   mKIAA1124   996 GPTPAGLPRQPPS    1008 

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