hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg02140/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1108  ( 1266 res)   mbg02140

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
TBC      Domain in Tre-2, BUB2p, and Cdc16p. Probable   311.0    8.2e-89   1
PTB      Phosphotyrosine-binding domain, phosphotyros   169.5    3.3e-46   2

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PTB        1/2      27   175 ..     1   156 []    45.1  9.5e-09
PTB        2/2     179   389 ..     1   156 []   126.4  3.1e-33
TBC        1/1     895  1115 ..     1   310 []   311.0  8.2e-89

Alignments of top-scoring domains:
PTB: domain 1 of 2, from 27 to 175: score 45.1, E = 9.5e-09
                   *->segvsfeVkYLGsvevpearkSlapgkglqvlqeairklr.......
                      ++ v f ++ +Gs++v + +        + +l +  +++r+ +++ +
   mKIAA1108    27    EVSVDFGLQLVGSLPVHSLT-------TMPMLPWVVAEVRrlsgqcs 66   

                   sekkkpqkvilsvSsdgvklidektk.........qvlaehplrrIsfca
                   ++ ++++ v l+vS++g+++  +  k+++ ++     + e+  +r++   
   mKIAA1108    67 KKEPRTKQVRLWVSPSGLRCEPDLEKsqpwdplicSSIFECKPQRVHKLI 116  

                   adpqrwntGgdgstdddrvFgyiardpgssgSnrgtsrfaCHVFrcekaa
                   + +           +d+++F+  ++++ +++      +  C+VF+ ++  
   mKIAA1108   117 HNS-----------HDPSYFACLIKEDAAHR------QSLCYVFKADDQT 149  

                   .aedialaigqaFqvayelklkarse<-*
                   ++++i+++i+qa + a ++ l++ se   
   mKIAA1108   150 kVPEIISSIRQAGKIARQEELRCPSE    175  

PTB: domain 2 of 2, from 179 to 389: score 126.4, E = 3.1e-33
                   *->segvsfeVkYLGsvevpearkSlapgkglqvlqeairklr.......
                        +++f+V+++G v v++++      +++++++e+i+k+ + + +++
   mKIAA1108   179    TFAKKFKVLFCGRVTVAHKK------APPALIDECIEKFNhvscgrr 219  

                   ..................................................
                   ++ + ++++++ +++++ +++ ++++ ++   +++ ++ + ++++ ++ +
   mKIAA1108   220 tdweaptgqpsapgprpmrksfsqpglrslafrkefqdaslrsstfssfd 269  

                   ................sekkkpqkvilsvSsdgvklidektkqvlaehpl
                   ++ +++  ++++  ++ ++++++++++ +  + v li+++tk++++e+++
   mKIAA1108   270 ndienhligghnvvqpTDMEENRTMLFTIGQSEVYLISPDTKKIALEKNF 319  

                   rrIsfcaadpqrwntGgdgstdddrvFgyiardpgssgSnrgtsrfaCHV
                   + Isfc++++           +++++Fg+i+r++++ g  +g ++f C+V
   mKIAA1108   320 KEISFCSQGI-----------RHVDHFGFICRECSGGG--SGGFHFVCYV 356  

                   Frcekaa.aedialaigqaFqvayelklkarse<-*
                   F+c+++a +++i+ +++qaF va+ +++++ ++   
   mKIAA1108   357 FQCTNEAlVDEIMMTLKQAFTVAAVQQTAKAPA    389  

TBC: domain 1 of 1, from 895 to 1115: score 311.0, E = 8.2e-89
                   *->vrkGvppslRgeVWklLlnaqpmntsnweraqkakdaesqflvvndd
                      v++Gvp+++Rge+Wk+L+++ + ++  + ++q+              
   mKIAA1108   895    VGQGVPRHHRGEIWKFLAEQFHLKHPFPSKQQP-------------- 927  

                   rlkdeYsrllnqtapkdkstdleqavssnnkdfeeqPLsiwnffqdndsl
                    ++ +Y +ll++  ++++                                
   mKIAA1108   928 -KDVPYKELLKKLTSQQH-------------------------------- 944  

                   dqIekDlkRTfpelsfFqfrsrdnqkevllddengpgqesLrrvLkaYsl
                    +I +Dl RTfp++++F               + g+gq sL+++LkaYsl
   mKIAA1108   945 -AILIDLGRTFPTHPYFSA-------------QLGAGQLSLYNILKAYSL 980  

                   ynpehivgYcQGmnflaapLLlvmpiydEedAFwcfvkLmerylpnflfk
                   +++e  vgYcQG++f+a++LLl+m   +Ee+AF ++++Lm+++++++ + 
   mKIAA1108   981 LDQE--VGYCQGLSFVAGILLLHM---SEEEAFKMLKFLMFDMGLRKQY- 1024 

                   dtnnfytpdlsglqadqlvldslleeylPeLykHLqeqdkqskkkhvdkl
                         +pd+  lq+++++l++ll++y+ +Ly+HL+e+            
   mKIAA1108  1025 ------RPDMIILQIQMYQLSRLLHDYHRDLYNHLEEH------------ 1056 

                   eidpslyalrWfLtlFarelPledvlRiwDvlfaellrlgseflfkiala
                   ei pslya++WfLt+Fa+++Pl++v+R++D++f++    gse++fk+al+
   mKIAA1108  1057 EIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQ----GSEVIFKVALS 1102 

                   iLklnedkllkld<-*
                   +L ++++++l++    
   mKIAA1108  1103 LLGSHKPLILQHE    1115 

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