hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mpg/mpg00309/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1101  ( 592 res)   mpg00309

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    250.9    1.1e-70   1
TyrKc    Tyrosine kinase, catalytic domain               54.6    1.6e-14   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
S_TKc      1/1      96   356 ..     1   231 []   250.9  1.1e-70
TyrKc      1/1      96   356 ..     1   280 []    54.6  1.6e-14

Alignments of top-scoring domains:
S_TKc: domain 1 of 1, from 96 to 356: score 250.9, E = 1.1e-70
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik........erilrE
                      Yel +++G+Ga ++V  a+    +++vAiK+i+ ++ +++ + +l+E
   mKIAA1101    96    YELQEVIGSGATAVVQAAYCAPKKERVAIKRINlekcqtsmDELLKE 142  

                   ikiLkk.dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrgrrg
                   i+ +++ +HPNIV +y +f+ +d+l+lVm +++G  G+++d++k+   +g
   mKIAA1101   143 IQAMSQcHHPNIVSYYTSFVVkDELWLVMKLLSG--GSVLDIIKHIVAKG 190  

                   lrk..vlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLdshvKla
                    +k++vl+E++++ ++r++l++LeYLH++g iHRD+K  NiLL       
   mKIAA1101   191 EHKsgVLDEpTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGF----- 235  

                   DFGlArql........ttfvGTpeYmAPEvl....gYgkpavDiWSlGci
                      lA+  + ++++ ++tfvGTp +mAPEv+++ +gY++ ++DiWS+G++
   mKIAA1101   236 ---LATGGditrnkvrKTFVGTPCWMAPEVMeqvrGYDF-KADIWSFGIT 281  

                   lyElltGkpPFp..qldlifkkig....................Speakd
                    +El+tG  P+++  +++++ + + +++++ +++  +++  +++ ++++ 
   mKIAA1101   282 AIELATGAAPYHkyPPMKVLMLTLqndppsletgvqdkemlkkyGKSFRK 331  

                   LikklLvkdPekRlta.eaLedeldikaHPff<-*
                   +i+ +L+kdPekR+ta e+L+       H ff   
   mKIAA1101   332 MISLCLQKDPEKRPTAaELLR-------HKFF    356  

TyrKc: domain 1 of 1, from 96 to 356: score 54.6, E = 1.6e-14
                   *->ltlgkkLGeGaFGeVykGtlk...ieVAVKtLkeda....keeFlrE
                       +l +++G+Ga  +V  +   ++++ VA+K ++ ++ ++++ e+l+E
   mKIAA1101    96    YELQEVIGSGATAVVQAAYCApkkERVAIKRINLEKcqtsMDELLKE 142  

                   akiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLldyL
                   ++ M++   +HpNiV  +   + +       + l++vm + +gG+ ld +
   mKIAA1101   143 IQAMSQC--HHPNIVSYYTSFVVK-------DELWLVMKLLSGGSVLDII 183  

                   rknrpk........lslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcL
                    k+   +++++++ l  ++   +   + +G eYL++++ +HRD  A N+L
   mKIAA1101   184 -KHIVAkgehksgvLDEPTIATILREVLEGLEYLHKNGQIHRDVKAGNIL 232  

                   vgenkvvKIsDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWmAP
                   +g                + +       d  r k    + ++    WmAP
   mKIAA1101   233 LGFLA-------------TGG-------DITRNKV--RKTFVGTPCWMAP 260  

                   Esl..kdgkFtskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevley
                   E++++  g + +k D+WSFG++  E+ t  ++ +        + + ++  
   mKIAA1101   261 EVMeqVRG-YDFKADIWSFGITAIELATGAAPYHKY-----PPMKVLMLT 304  

                   lkkGyRlpkPendl...p.iSsvtCPdelYd.lMlqCWaedPedRPtFse
                   l++   +p  e + ++++ +       + ++++++ C + dPe+RPt +e
   mKIAA1101   305 LQND--PPSLETGVqdkEmL---KKYGKSFRkMISLCLQKDPEKRPTAAE 349  

                   l..verl<-*
                   l +++++   
   mKIAA1101   350 LlrHKFF    356  

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