hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpg/mpg00309/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1101  ( 592 res)   mpg00309

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       203.4    3.5e-57   1
Pkinase_Tyr Protein tyrosine kinase                      81.4    1.9e-20   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Pkinase       1/1      96   356 ..     1   287 []   203.4  3.5e-57
Pkinase_Tyr   1/1      96   356 ..     1   272 []    81.4  1.9e-20

Alignments of top-scoring domains:
Pkinase: domain 1 of 1, from 96 to 356: score 203.4, E = 3.5e-57
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      yel e++GsG+ ++V  a+     ++VA+K+i+++k   ++d+ +  
   mKIAA1101    96    YELQEVIGSGATAVVQAAYCAPKKERVAIKRINLEKCQTSMDELLK- 141  

                   rsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrlldLfdyls.
                     Eiq +  ++HpNIv ++ +f  kd+l+lV+ ++ gG    +  d++++
   mKIAA1101   142 --EIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGG----SVLDIIKh 185  

                   .e...trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILl
                    + ++ +++g+l  +e ++  i++++l+gleYLH+ng iHRD+K  NILl
   mKIAA1101   186 iVakgEHKSGVL--DEPTIATILREVLEGLEYLHKNGQIHRDVKAGNILL 233  

                   d..engvvdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggn
                       +g+                 ++++   +tfvGTp +mAPEv    +
   mKIAA1101   234 GflATGGD----------------ItRNKvRKTFVGTPCWMAPEVMEQVR 267  

                   gygtkvDvWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefd
                   gy+ k+D+WS+G++ +el+tG  P+         +++++ ++l+      
   mKIAA1101   268 GYDFKADIWSFGITAIELATGAAPYHKY-----PPMKVLMLTLQN----- 307  

                   spewdsisrse.fr.r.l.pnlseeakdLikkcLnkDPskRltaeeilqH
                       d++s+++++++++  ++  +++++ i+ cL+kDP+kR+ta+e+l H
   mKIAA1101   308 ----DPPSLETgVQdKeMlKKYGKSFRKMISLCLQKDPEKRPTAAELLRH 353  

                   Pwf<-*
                   ++f   
   mKIAA1101   354 KFF    356  

Pkinase_Tyr: domain 1 of 1, from 96 to 356: score 81.4, E = 1.9e-20
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtL.keigasseei
                       +l++++G+Ga  +V  +++      +k  VA+K ++ e ++  +  
   mKIAA1101    96    YELQEVIGSGATAVVQAAYCA----PKKERVAIKRInLE-KCQTS-- 135  

                   eredFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGd
                    ++++l+E++ M++  +HpNiV+++   +  ++     l++V+ +  gG+
   mKIAA1101   136 -MDELLKEIQAMSQC-HHPNIVSYYTSFVV-KDE----LWLVMKLLSGGS 178  

                   LldfLrkhr.....egrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAA
                    ld  ++   ++++  + L+ ++   + +++ +G+eYL+ ++ +HRD+ A
   mKIAA1101   179 VLDIIKHIVakgehKSGVLDEPTIATILREVLEGLEYLHKNGQIHRDVKA 228  

                   RNcLVsenlvVKIsDFGLaRdi.ynddyY.vrkkgggklPvkWmAPEslk
                    N+L++               + +  d  + ++++       WmAPE++ 
   mKIAA1101   229 GNILLG--------------FLaTGGDITrNKVRKTFVGTPCWMAPEVME 264  

                   ygk.FtskSDVWSFGVlLWEiftlGeqPFYpgmsnee............v
                     +++  k D+WSFG++  E+ t G+ P Y   ++      + +++++++
   mKIAA1101   265 QVRgYDFKADIWSFGITAIELAT-GAAP-YHKYPPMKvlmltlqndppsL 312  

                   lellyedGyRLprPenCPdelYdlMlqCWaedPedRPtFsel..verL<-
                      + +d + L++     +   +++ +C ++dPe+RPt +el ++ ++  
   mKIAA1101   313 ETGV-QDKEMLKKY---GKSFRKMISLCLQKDPEKRPTAAELlrHKFF   356  

                   *
                    
   mKIAA1101     -   -    

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