hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj15083/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1099  ( 981 res)   mfj15083

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
ArfGap   Putative GTPase activating protein for Arf     184.1    2.3e-51   1
PH       PH domain                                       52.5    9.2e-12   1
Ank      Ankyrin repeat                                  47.5    2.9e-10   2
Ras      Ras family                                       5.0    7.9e-09   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Ras        1/1     197   355 ..     1   174 []     5.0  7.9e-09
PH         1/1     471   712 ..     1    92 []    52.5  9.2e-12
ArfGap     1/1     733   853 ..     1   137 []   184.1  2.3e-51
Ank        1/2     892   924 ..     1    33 []    39.4  8.3e-08
Ank        2/2     925   957 ..     1    33 []     8.2       13

Alignments of top-scoring domains:
Ras: domain 1 of 1, from 197 to 355: score 5.0, E = 7.9e-09
                   *->KlVlvGDgGVGKSsLliRFtdnkFpeeYipTIGvD....Fytktvev
                      K+ +vG+ + GKS+L++R+ ++++++e      + ++++ + k ++v
   mKIAA1099   197    KVGIVGNLASGKSALVHRYLTGTYVQE------ESpeggRFKKEIVV 237  

                   dgktvkLqIWDTAGQErFralrpaYYRgAqGfLLVYDITsrdSFenvkkW
                   dg+ + L I D  G         ++    ++++ V++  ++ SF+ v ++
   mKIAA1099   238 DGQSYLLLIRDEGG-----PPEAQFAMWVDAVIFVFSLEDEISFQTVYHY 282  

                   leeilrhadkdenvpivLVGNKcDLeddedlele.kqkRqVsteeGealA
                   ++   ++ +  e +p vLVG+  D  +       ++  R+++  ++++l 
   mKIAA1099   283 YSRMANYRNTSE-IPLVLVGTQ-DAIS------StNP-RVIDDVRARKLS 323  

                   kelgAlpFmETSAKtneNVeeaFeelareilk<-*
                    +l+ + ++ET A  + NVe +F+++a++i +   
   mKIAA1099   324 NDLKRCTYYETCATYGLNVERVFQDVAQKIVA    355  

PH: domain 1 of 1, from 471 to 712: score 52.5, E = 9.2e-12
                   *->vikeGwLlkkg...gkkswkkRyfvLfn.dvLlyykdkk....kkpk
                      +ik+G Llk+++++ +k+wkk y++L++++vL y+ + ++  +  + 
   mKIAA1099   471    PIKQGMLLKRSgksLNKEWKKKYVTLCDnGVLTYHPSLHdymqNVHG 517  

                   gsipLsgiqvekvpdn..................................
                   + i+L   +v+ + + +++ ++   + +++++++  ++ ++ + ++++++
   mKIAA1099   518 KEIDLLRTTVKVPGKRppratsacapissprtnglakdmsslhispnsgn 567  

                   ..................................................
                    ++ ++++  ++ +  + ++++++ ++++ + ++ ++ ++ +   ++  +
   mKIAA1099   568 vtsasgsqmasgislvsfnsrpdgmhqrsysvssadqwsdatviansais 617  

                   ..................................................
                   ++++ +++  ++++ +++++++ +++++++ +++++++++++++ + ++ 
   mKIAA1099   618 sdtglgdsvcsspsissstspkldpppsphanrkkhrrkkstsnfkadgl 667  

                   .......krkncFeirt.dretlllqaeseeerkeWvkaiqsair<-*
                   +++ ++++++  F i++ +++t++++a+++eer+ Wv+ai+s+i    
   mKIAA1099   668 sgtaeeqEENLEFIIVSlTGQTWHFEATTYEERDAWVQAIESQIL    712  

ArfGap: domain 1 of 1, from 733 to 853: score 184.1, E = 2.3e-51
                   *->qrvlqlLrsldpgNkkCfDCgavpnPtWaSvnlGvflCieCSGiHRn
                      + +lq +r+ + gN++C DC+   nP WaS+nlG++ CieCSGiHRn
   mKIAA1099   733    AMALQSIRNMR-GNSHCVDCDT-QNPNWASLNLGALMCIECSGIHRN 777  

                   LfGvHiSkVnvRSltLDsWtpeeLrklesckgGNenansfwEsnlddfsl
                   L G+H+S+V  RSl+LD W+ e ++++    +GNe ans+wE     + +
   mKIAA1099   778 L-GTHLSRV--RSLDLDDWPMELIKVMS--SIGNELANSVWEEGSQGRTK 822  

                   kpkdsdaaavKCqddrqkyesfiaaKYeeklfvlkeeqee<-*
                   ++ ds          r+++e +i+aKYe+klf+ ++++ e   
   mKIAA1099   823 PSLDST---------REEKERWIRAKYEQKLFLAPLPCTE    853  

Ank: domain 1 of 2, from 892 to 924: score 39.4, E = 8.3e-08
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                      dG+T+LHlA+++gn+ +++lL+ +G d+ a+d    
   mKIAA1099   892    DGRTALHLACRKGNVVLAQLLIWYGVDVMARDA    924  

Ank: domain 2 of 2, from 925 to 957: score 8.2, E = 13
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                      +G+T+L +A +  + e++  Ll++G+          
   mKIAA1099   925    HGNTALAYARQASSQECIDVLLQYGCPDERFVL    957  

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