hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg00289/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1091  ( 1217 res)   mbg00289

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
DENN     DENN (AEX-3) domain                            314.0    1.8e-90   1
RUN      RUN domain                                     176.2    5.3e-49   1
dDENN    dDENN domain                                   118.2    1.6e-31   1
PLAT     PLAT/LH2 domain                                 64.3    2.7e-15   1
uDENN    uDENN domain                                    62.1    1.2e-14   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
uDENN      1/1       1    68 [.     1   108 []    62.1  1.2e-14
DENN       1/1     132   320 ..     1   231 []   314.0  1.8e-90
dDENN      1/1     442   518 ..     1    81 []   118.2  1.6e-31
RUN        1/1     739   876 ..     1   174 []   176.2  5.3e-49
PLAT       1/1     887   989 ..     1   130 []    64.3  2.7e-15

Alignments of top-scoring domains:
uDENN: domain 1 of 1, from 1 to 68: score 62.1, E = 1.2e-14
                   *->carLfDyfVvVgldkkpsglgPDelagdneylPellrqFPSKllahy
                                                          r+F+SK+la y
   mKIAA1091     1    ------------------------------------RTFKSKVLARY 11   

                   kedhedepfdlksipkFCfPegldsvsvrevnalrdpqfFsFvLTdeDsk
                   +e+++++pfd++++ ++C+P+gl + +++++   r+pqf+ F++T+eD++
   mKIAA1091    12 PENVDWNPFDQDAVGMLCMPKGLAFKTQADP---REPQFHAFIITREDGS 58   

                   RtryGfCltfy<-*
                   R ++Gf ltfy   
   mKIAA1091    59 R-TFGFALTFY    68   

DENN: domain 1 of 1, from 132 to 320: score 314.0, E = 1.8e-90
                   *->rvpksiCliSrlpffeaFrkvLlelkrvldssqasslppssglksgk
                      +v k+iCli++++f++a+r vL++l++ ++s+q+++lp         
   mKIAA1091   132    YVSKCICLITPMSFMKACRSVLQQLHQAVTSPQPPPLP--------- 169  

                   srdtvwrvltgvlevLhdirElEslirnLlyeVplPapGktirvkvvvls
                                        lEs+i+n+lyeVplP+pG+++++++v++ 
   mKIAA1091   170 ---------------------LESYIYNVLYEVPLPPPGRSLKFSGVYG- 197  

                   sgvkHyrplelilfplpdplplpledfdlaelFeaLGvenvlqLfaaaLl
                             +i++++p +++lpl+df+++e+Fe+LGvenv+qLf++aLl
   mKIAA1091   198 ----------PIICQRPSTNELPLFDFPVKEVFELLGVENVFQLFTCALL 237  

                   ErkiLflSsklsrLsscchAlvaLLYPleWqhpyIPvLPasLlsAEdvLc
                   E++iL++S++++rL++++++++aL++P++Wqh+y+P+LPasLl   ++L+
   mKIAA1091   238 EFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLL---HFLD 284  

                   APtPFlIGVhssffelvkdlplei..dvvvVDLDtn<-*
                   AP+P+l+G+hs+ ++++ +l+l+++ ++++VD+D++   
   mKIAA1091   285 APVPYLMGLHSNGLDDRSKLELPQeaNLCFVDVDNH    320  

dDENN: domain 1 of 1, from 442 to 518: score 118.2, E = 1.6e-31
                   *->lddqvreaFLrfFNasllggYrnfLryprkape.wegardevvtFqk
                      l+ q+re+F ++F  +++++Y++f+++p++++e+w+++r+++++F+k
   mKIAA1091   442    LNIQIREVFANRF-TQMFADYEVFVIQPSQDKEsWFTNREQMQNFDK 487  

                   eaFLksrprssqraFlsrlletQAVemFaeFIeeR<-*
                   ++FL+++p+ ++ +Flsr+letQ   mFa+FI+++   
   mKIAA1091   488 ASFLSDQPEPYL-PFLSRFLETQ---MFASFIDNK    518  

RUN: domain 1 of 1, from 739 to 876: score 176.2, E = 5.3e-49
                   *->tLCpaleAllsHGLkrpelltgaihpwafiedaaagefekaalsvls
                      + +++++Al+sH+L+++                  ++++k ++++ls
   mKIAA1091   739    QVKQGKSALWSHLLHYQ-----------------ENRQRKLTSGSLS 768  

                   sssllldsqrslgcdtnnldpsfkvlpvaeslkhivsqieqLaeKrSsvi
                   +s++llds+r++      +d+s+ + p++ sl +++++i++++e     i
   mKIAA1091   769 TSGILLDSERRK------SDASAVMSPLRISLIQDMRHIQNIGE-----I 807  

                   ktavgrgRKyAWiRlaLneksLssylklLlsdeellrkyYkpnAlLrdpS
                   kt+vg+ R  AW+Rl++++k+Ls++lk+Llsd+el++k+Yk++A+Lr++ 
   mKIAA1091   808 KTDVGKAR--AWVRLSMEKKLLSRHLKQLLSDHELTKKLYKRYAFLRCD- 854  

                   deegCeillslLqgLsaldFsLdlkfe<-*
                    +e+ e++l++L +++a+d++   +f+   
   mKIAA1091   855 -DEK-EQFLYHLLSFNAVDYF---CFT    876  

PLAT: domain 1 of 1, from 887 to 989: score 64.3, E = 2.7e-15
                   *->vsyqlivatggdstgagttgkvgislyGeegeseqipllkgelkslp
                      +++ + ++ +g   g++ t++ +i++ Ge ge+              
   mKIAA1091   887    HILIVPSKKLG---GSMFTANPWICISGELGET-------------- 916  

                   tlgagpgstfsftfdvdedlGelgavkiknehsglnswsptspewflksi
                   ++ + p ++ ++tf++ ++lG l  v+i +++sgl++      +w ++ +
   mKIAA1091   917 QILQIPRNVLEMTFEC-QNLGKLTTVQIGHDNSGLYA------KWLVECV 959  

                   tvedgptqgkvhFpcnsWvypatgdeylslrif<-*
                    v++  t+++++Fpc +W+ +    ++ sl+     
   mKIAA1091   960 MVRNEVTGHTYKFPCGRWLGKG--MDDGSLE-R    989  

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