hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mph/mph00524/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1090  ( 857 res)   mph00524

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
SET      SET (Su(var)3-9, Enhancer-of-zeste, Trithora   158.3    7.5e-43   1
PHD      PHD zinc finger                                112.3    5.4e-29   5
PWWP     domain with conserved PWWP motif                92.6    4.6e-23   1
PostSET  Cysteine-rich motif following a subset of SE    27.4      0.002   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PHD        1/5     161   203 ..     1    39 []    37.1  2.3e-06
PHD        2/5     208   255 ..     1    39 []    16.7      1.2
PHD        3/5     256   309 ..     1    39 []    -3.5       66
PHD        4/5     325   365 ..     1    39 []    49.6    4e-10
PWWP       1/1     370   432 ..     1    84 []    92.6  4.6e-23
SET        1/1     555   678 ..     1   114 []   158.3  7.5e-43
PostSET    1/1     679   695 ..     1    17 []    27.4    0.002
PHD        5/5     733   776 ..     1    39 []    43.2  3.5e-08

Alignments of top-scoring domains:
PHD: domain 1 of 5, from 161 to 203: score 37.1, E = 2.3e-06
                   *->yC.vCgk.g.llqCdkgCdrwyHv.Clgppleepdg.wyCprCk<-*
                      +C++C k+g+ll+C++ C+ ++H+ Clg++ + p+g++ C +C    
   mKIAA1090   161    VCqLCEKtGsLLLCEGPCCGAFHLaCLGLSRR-PEGrFTCTECA    203  

PHD: domain 2 of 5, from 208 to 255: score 16.7, E = 1.2
                   *->yC.vCgk..g.llqCd.kgCdrwyHv.Clgpple..epdg.wyCprC
                       C vC++++ +   C   +C++ yH  C++  +++  ++ +++Cp +
   mKIAA1090   208    SCfVCKEskMeVKRCVvNQCGKFYHEaCVKKYPLtvFESRgFRCPLH 254  

                   k<-*
                   +   
   mKIAA1090   255 S    255  

PHD: domain 3 of 5, from 256 to 309: score -3.5, E = 66
                   *->yC.vCgk..........g.llqCdkgCdrwyHv...Clgpple.epd
                       C  C+ ++++++++++g+++ C  +C+++yH ++ Cl    + + +
   mKIAA1090   256    -CmSCHAsnpsnprpskGkMMRCV-RCPVAYHGgdaCLAAGCSvIAS 300  

                   g.wyCprCk<-*
                    + +C  +    
   mKIAA1090   301 NsIICTGHF    309  

PHD: domain 4 of 5, from 325 to 365: score 49.6, E = 4e-10
                   *->yC.vCgk.g.llqCdkgCdrwyHv.Clgppleepdg.wyCprCk<-*
                      +C vC k+g+ll+C+  C+ ++H++Cl+++++  dg+w+C+ C+   
   mKIAA1090   325    WCfVCSKgGsLLCCE-ACPAAFHPdCLNIEMP--DGsWFCNDCR    365  

PWWP: domain 1 of 1, from 370 to 432: score 92.6, E = 4.6e-23
                   *->fkpGDlVwAKmkGFPwWPAlvvspketpsnirktgvviphpplevlk
                      +++ D++w+K + ++wWPA+v++pk +p ni                
   mKIAA1090   370    LHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQ--------------- 401  

                   leeeaknkrkenlypVlFFgdkdtrawvsssklfPLt<-*
                        k+k+ ++++pV+FFg+kd+ +w++++++fP++   
   mKIAA1090   402 -----KMKHEIGEFPVFFFGSKDY-YWTHQARVFPYM    432  

SET: domain 1 of 1, from 555 to 678: score 158.3, E = 7.5e-43
                   *->aklevfkskgkGwGlratedIpkGefIleyvGeii............
                      +  ++ k++gkGwGl+a++dI+kGef+ eyvGe+i++++   + +  
   mKIAA1090   555    PETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIdeeecmarikya 601  

                   .......fylfd.....ciDatranggkGniarfiNHSCePNcelifvev
                   ++++ ++fy+   ++++ iDa      kGn++rf+NHSC+PNce+ ++ v
   mKIAA1090   602 hendithFYMLTidkdrIIDAGP----KGNYSRFMNHSCQPNCETLKWTV 647  

                   dgfdprgasdsadprivifAlrdIkpGEELtidYgddyege<-*
                   +g          d+r+++fA  dI++G+ELt++Y+ d+ g+   
   mKIAA1090   648 NG----------DTRVGLFAVCDIPAGTELTFNYNLDCLGN    678  

PostSET: domain 1 of 1, from 679 to 695: score 27.4, E = 0.002
                   *->kkqpClCGaanCrGfLg<-*
                      +k  C+CGa+nC+GfLg   
   mKIAA1090   679    EKTVCRCGASNCSGFLG    695  

PHD: domain 5 of 5, from 733 to 776: score 43.2, E = 3.5e-08
                   *->yC.vCgk.g.llqCd.kgCdrwyHv.Clgppleepdg.wyCprCk<-
                       C  Cg++g+l++Cd+k C ++yH++Clg+ ++ p g+w Cp++   
   mKIAA1090   733    ECfRCGDgGqLVLCDrKFCTKAYHLsCLGLGKR-PFGkWECPWHH   776  

                   *
                    
   mKIAA1090     -   -    

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