hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /data11/genetics/InterProScan/iprscan/data/TIGRFAMs_HMM.LIB
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj06035/w3open/interpro/cnk_1/seq.in
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query:  mKIAA1088  ( 1211 res)   mfj06035

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
rad3     rad3: DNA repair helicase (rad3)               419.8   2.5e-122   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
rad3       1/1      10   747 ..     1   813 []   419.8 2.5e-122

Alignments of top-scoring domains:
rad3: domain 1 of 1, from 10 to 747: score 419.8, E = 2.5e-122
                   *->ellvyfpyekiyninAEpeqrsymrdlkrsLDrgdeailsaEyDEmP
                      + +v fp+ + y     p+q +ym  + + L  + + il     E+P
   mKIAA1088    10    GVTVDFPFQP-Y-----PCQQEYMTKVLECLQKKVNGIL-----ESP 45   

                   sGtGKTikGGRisDKDYkldelySskvSlLslilayqqekPlnGDRFDvt
                   +GtGKT+                     lL+++la+qq+         + 
   mKIAA1088    46 TGTGKTL--------------------CLLCSTLAWQQHLRDAVSSLKIA 75   

                   nq.........................evl....KiiYaSRThSqleqav
                      +++   +++ ++ ++    ++++ e++++ +KiiYaSRThSql q++
   mKIAA1088    76 ERvqgelfasrtlsswgsaaaasgdsiECYtdipKIIYASRTHSQLTQVI 125  

                   eELrKlmsyytpeigyesskflglslaSRKnLClnpeVskerqgkavnek
                    ELr++         y      +++l SR++LC++peV k     + n++
   mKIAA1088   126 RELRNTA--------YRPK---VCVLGSREQLCIHPEVKK----QESNHM 160  

                   CikltvskikeqrrekpktRGLVnkeaCeFYenldelrdrPDvkevedll
                    i+l ++k+               +++C+FY+n +++        +e  l
   mKIAA1088   161 QISLCRKKVA--------------SRSCHFYNNVEAK-------FLEQDL 189  

                   lseimdiedlveyGellglCPYfatRkalpfAniVilpYqYLLdPkiRsa
                      i diedlv+ G + ++CPY+++R +  +A i+  pY+YLLd k R+a
   mKIAA1088   190 ATPILDIEDLVKNGSKQKMCPYYLSRNMKQQADIIFMPYNYLLDAKSRKA 239  

                   lsleLkkdYSDsIVIFDEAHNldnvciSslSRKLsniskrslkrcskeia
                    s++Lk      +VIFDEAHN++ +c++s+S    +++ r+++   + i+
   mKIAA1088   240 HSIDLKG----TVVIFDEAHNVEKICEESAS---FDLTPRDVASGLEIIN 282  

                   eyfekieerklrlirevdarkGAFGSAlldelqklvegLkqedlltdked
                   ++ e    +      + ++         +  + +   ++  ed++  +  
   mKIAA1088   283 QVLEEQARVT-----QQGELQ----QEFIVDTSSSGLNMELEDIAK-LKM 322  

                   iflanpvlpkevlpSqLeavpgnirkaeiflhkLsryleylklalKvlgv
                   i+l    l++ ++     ++pg  r  +   +   ++     +     g 
   mKIAA1088   323 ILLR---LEEAIDA---VQLPGDDRGVTKPGSYIFELFAEAQITFQTKGC 366  

                   vselpdafleklkekteidrkplrfcseRlsnllreleithvedfsalvl
                   + e+ d+++++l   t +   + ++   +l + +    + +++  s+ +l
   mKIAA1088   367 ILESLDQIIQHLAGRTGVFTNTAGL--QKLMDIIQIVFSVDPPEGSPGSL 414  

                   l.......ftfatlvltytngflegiepyeqrnktvenpilkfmcLDPSi
                   ++ + +++ ++     t  + ++       +      + +l + c+ PS 
   mKIAA1088   415 VglgishsYKVHIHPETSHRRAAKRSDAWSTTASRKQGKVLSYWCFSPSQ 464  

                   alkpvferGarSVilaSGTLSPldaftkiLgfntvlkdsprfSCthvlkr
                   ++++++ +G+r  il+SGTL Pl+ f   ++  +++  ++     h++++
   mKIAA1088   465 SMRELVCQGVRTLILTSGTLAPLSSFALEMQIPFPVCLEN----PHIIDK 510  

                   enlltlivtrGsDqvalsstFetRkdpslvrnHlgellvelskiiPKKdG
                   ++l + iv rG+D+v lss +++R ++  + + lg +l + + ++P   G
   mKIAA1088   511 NQLWVGIVPRGPDGVQLSSAYDKRFSEECLSS-LGKALSNIARVVP--HG 557  

                   iVvFFpSYsyLeqiVstWkemGilenSNESFWEKiekkKliFvEtkDapq
                   ++vFFpSY ++e  +  W+ +G+           +e+ K++FvE++ +  
   mKIAA1088   558 LLVFFPSYPVMEKSLEFWQVQGLARK--------VEALKPLFVEPRNK-G 598  

                   EtsdalerYkqavs..eGrGAvLLsVagGKvSEGIDFsddlGRAVImvGi
                     s++++ Y q v+++++ GA  L+V++GK SEG DFsd  GR+VI+ G+
   mKIAA1088   599 SFSEVIDAYYQQVAspASNGATFLAVCRGKASEGLDFSDMNGRGVIVTGL 648  

                   PYPnifdeeytesrvlkarleflrdqyqirensqtkdFyefdAMRavnQa
                   PYP+  d +++++   +++++++++      + q  ++y+  A RavnQa
   mKIAA1088   649 PYPPRMDPRVVLKMQFLDEMRGRSGVGGQCLSGQ--EWYQQQASRAVNQA 696  

                   iGRviRhkdDYGsivLlDkRYaRsdkRkkLPkWiqdtiqssdlngstDea
                   iGRviRh+ DYG+i L D R+a  d R +LP W++ ++ + d++g    +
   mKIAA1088   697 IGRVIRHRHDYGAIFLCDHRFAYADARAQLPSWVRPYLKVYDNFG---HV 743  

                   Irlt<-*
                   Ir     
   mKIAA1088   744 IRDV    747  

//