hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mia/mia33062/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1038  ( 715 res)   mia33062

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
GTP_EFTU    Elongation factor Tu GTP binding domain     291.7    8.9e-84   1
GTP_EFTU_D3 Elongation factor Tu C-terminal domain      123.6    3.8e-33   1
GTP_EFTU_D2 Elongation factor Tu domain 2                48.0    2.1e-10   1
MMR_HSR1    GTPase of unknown function                   -9.5       0.05   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
MMR_HSR1      1/1     292   440 ..     1   140 []    -9.5     0.05
GTP_EFTU      1/1     289   512 ..     1   299 []   291.7  8.9e-84
GTP_EFTU_D2   1/1     533   600 ..     1    75 []    48.0  2.1e-10
GTP_EFTU_D3   1/1     606   714 ..     1   112 []   123.6  3.8e-33

Alignments of top-scoring domains:
MMR_HSR1: domain 1 of 1, from 292 to 440: score -9.5, E = 0.05
                   *->lrvaivGrPNVGKSTLiNaLtgk....................krai
                      l  +++G   +GKSTL+  ++   ++ ++++ ++ ++++++ +k + 
   mKIAA1038   292    LNLVVIGHVDAGKSTLMGHMLYLlgnvnkrtmhkyeqeskkagKASF 338  

                   VsdyP..........GtTrdpnegrveldgrqiilvDTPGiiegaskgeg
                   +  +  +++++++++G+T d+   ++e+  + i+l D PG  +  +    
   mKIAA1038   339 AYAWVldetgeererGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMIT 388  

                   elgertleaieeaDlilfVvDase..........gltedytieeDleiad
                            + +aD++++VvDas+++ + + +++g t             
   mKIAA1038   389 --------GAAQADVAVLVVDASRgefeagfetgGQT------------- 417  

                   llydeerernleltLqelekkgkPvilvlNKiD<-*
                           r+  l+ + l+ +   + +++NK+D   
   mKIAA1038   418 --------REHGLLVRSLGVTQ--LAVAVNKMD    440  

GTP_EFTU: domain 1 of 1, from 289 to 512: score 291.7, E = 8.9e-84
                   *->krhrNigiiGHVDHGKTTLtdrLlyytgaisertleklegeakegge
                      k+ +N+++iGHVD+GK+TL++++ly +g + +rt+ k+e e+k++g 
   mKIAA1038   289    KQLLNLVVIGHVDAGKSTLMGHMLYLLGNVNKRTMHKYEQESKKAG- 334  

                   rkgsfklaaviDkmeeErERGITIksahvsfewkdededletkakegkkr
                    k+sf +a+v+D + eErERG+T+++  ++fe                  
   mKIAA1038   335 -KASFAYAWVLDETGEERERGVTMDVGMTKFE------------------ 365  

                   gnelTekrhiniIDTPGHvDFtkevirGlaqaDGAiLVVdAveGvmp.Gf
                       T + +i++ D+PGH DF+ ++i+G+aqaD A+LVVdA  G+++ Gf
   mKIAA1038   366 ----TTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEaGF 411  

                   .k.GQTrehlrlArqlgvppiilvVaiNKiDrvgaelklppvpeelyeel
                   + +GQTreh +l r lgv   +l+Va+NK+D v+       + +e+++e+
   mKIAA1038   412 eTgGQTREHGLLVRSLGVT--QLAVAVNKMDQVN-------WQQERFQEI 452  

                   ekevrellkpIgedfgvidlilaevaeddelmeyylegeeipiipiSalg
                     ++  +lk                         ++ ++++ +ip S+l 
   mKIAA1038   453 TGKLGHFLKQ-----------------------AGFKESDVAFIPTSGLS 479  

                   gdnidelsiknkLkkddlslvPwykgvSalknkgrdrgaiptLLealddy
                   g+n+ ++s+++       +l+ wykg               +LLe +d+ 
   mKIAA1038   480 GENLTARSQSS-------DLTTWYKG--------------MCLLEQIDS- 507  

                   lPsPe<-*
                   + +P+   
   mKIAA1038   508 FKPPQ    512  

GTP_EFTU_D2: domain 1 of 1, from 533 to 600: score 48.0, E = 2.1e-10
                   *->GtVatgRvesGtlkkGdeveigg.ngtkkyvpevtrVtslemfhg.l
                      G+ +tg++e G +  Gd++  +++n+t       ++ +++  + +++
   mKIAA1038   533    GFCVTGKIEAGYIQTGDRLLAMPpNET-------CTAKGITLHDEpV 572  

                   deavaGdnaGlivagiglkdaaikrGdvla<-*
                   d a aGd + l++ g ++    i++G++++   
   mKIAA1038   573 DWAAAGDHVNLTLVGMDIIK--INVGCIFC    600  

GTP_EFTU_D3: domain 1 of 1, from 606 to 714: score 123.6, E = 3.8e-33
                   *->ikphtkFeAqVyiLnkeeqIggRhtPffdgYtpqfycrTtdvtgkid
                      ik++t+F+A++ ++n e  I+ ++   +++ t  ++  +++++++++
   mKIAA1038   606    IKACTRFRARILVFNIEVPITKGFPVLLHYQTVSEPAVIKRLISVLN 652  

                   kltgkvkkvleegpemVmpGDnvivtvelikPiavEtFsdYPpggRFAiR
                   k tg+   v++++p+ + +G+n+ v+++ ++P+a+E ++d++++gRF++R
   mKIAA1038   653 KSTGE---VTKKKPKLLTKGQNALVELQTQRPVALELYKDFKELGRFMLR 699  

                   EGGrTVGaGvVteil<-*
                    GG TV+aGvVtei+   
   mKIAA1038   700 YGGSTVAAGVVTEIK    714  

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