hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg03568/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1028  ( 546 res)   mbg03568

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       256.9    2.8e-73   1
Pkinase_Tyr Protein tyrosine kinase                     -18.7      1e-10   1
Kdo         Lipopolysaccharide kinase (Kdo/WaaP) fami   -88.8       0.76   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Kdo           1/1      52   242 ..     1   223 []   -88.8     0.76
Pkinase_Tyr   1/1      65   378 ..     1   272 []   -18.7    1e-10
Pkinase       1/1      65   380 ..     1   287 []   256.9  2.8e-73

Alignments of top-scoring domains:
Kdo: domain 1 of 1, from 52 to 242: score -88.8, E = 0.76
                   *->defWqlqgkvvgeanGR.....rttwFvvaeklFGvngalrhYyRGg
                        + +++++v +  ++++ + +r+t+  v++            +R+ 
   mKIAA1028    52    AKLAAERERVEDLFEYEgckvgRGTYGHVYKA-----------RRKD 87   

                   lwgkLvrDryrfpGlgrtr....svrEfrllrrLreaGvpVPkpvAagav
                      +  +  y  +  + t+ + ++ rE +llr+L    v++++ v+    
   mKIAA1028    88 GKDE--KE-YALKQIEGTGismsACREIALLRELKHPNVIALQKVFLSHS 134  

                   kvgleryqAdLLtEklegaqDLvtwlaqWaddP.......paeelrqalw
                         ++  LL    e+  DL  +   ++    ++++ +++  + + l+
   mKIAA1028   135 ----D-RKVWLLFDYAEH--DLWHIIKFHRASKankkpmqLPRSMVKSLL 177  

                   eavGrlIakmHragvnHtDLnahnILldqeesvegkfkvwlIDfdKcrrr
                    ++   I+ +H+  v H+DL + nIL+  e+            ++++r +
   mKIAA1028   178 YQILDGIHYLHANWVLHRDLKPANILVMGEG------------PERGRVK 215  

                   lrvgdrWreknLarLkRSflKErGkrsigfteaDwaallrgY<-*
                   ++      +  +arL           s+  + aD   ++ +    
   mKIAA1028   216 IA------DMGFARLFN---------SPLKPLADLDPVVVTF    242  

Pkinase_Tyr: domain 1 of 1, from 65 to 378: score -18.7, E = 1e-10
                   *->lklg.kkLGeGaFGeVykGtlkgsgegtkikVAVKtLkeigasseei
                      ++  + k G+G +G+Vyk++ k  +++++ + A K + e g+  +  
   mKIAA1028    65    FEYEgCKVGRGTYGHVYKARRK--DGKDEKEYALKQI-E-GTGIS-- 105  

                   eredFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGd
                      +  rE++++++l +HpN++ L  v + +++     +++ + y+e+ d
   mKIAA1028   106 --MSACREIALLREL-KHPNVIALQKVFLSHSDRK---VWLLFDYAEH-D 148  

                   LldfLrkhr......egrpLtlkdLlsfalQiAkGMeYLesknfvHRDLA
                   L +  + hr ++ ++ + +L+ ++  s  +Qi +G  YL+++ + HRDL 
   mKIAA1028   149 LWHIIKFHRaskankKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLK 198  

                   ARNcLVs....enlvVKIsDFGLaRdiynddyYvrkkgggk.lPv...kW
                     N+LV ++++e + VKI+D G aR+     +    k  +   Pv  ++W
   mKIAA1028   199 PANILVMgegpERGRVKIADMGFARLF----NS-PLKPLADlDPVvvtFW 243  

                   m.APEslkygk.FtskSDVWSFGVlLWEiftlGeqP.F............
                   ++APE l   +++t + D+W+ G+   E++t   +P F+ ++++ +++++
   mKIAA1028   244 YrAPELLLGARhYTKAIDIWAIGCIFAELLT--SEPiFhcrqediktsnp 291  

                   .............................Ypgm.snee........vlel
                    ++++ ++  +  + + +++ ++ ++ ++Yp +++++++++  +++++++
   mKIAA1028   292 fhhdqldrifsvmgfpadkdwedirkmpeYPTLqKDFRrttyanssLIKY 341  

                   lyedGyRLprPenCPdelYdlMlqCWaedPedRPtFselverL<-*
                     e+     +P+    +++ l ++    dP +R t ++ +++    
   mKIAA1028   342 M-EKHKV--KPD---SKVFLLLQKLLTMDPTKRITSEQALQDP    378  

Pkinase: domain 1 of 1, from 65 to 380: score 256.9, E = 2.8e-73
                   *->yelle.klGsGsfGtVykakhkgtgk..iVAvKiikkrkekskkdkt
                      +e ++ k+G+G++G Vyka++k+  +++++A+K+i+  +++++ ++ 
   mKIAA1028    65    FEYEGcKVGRGTYGHVYKARRKDGKDekEYALKQIEGTGISMSACR- 110  

                   arrrsEiqilkrLsHpNIvrlidvfed..kdhlylVlEycegGLrlldLf
                        Ei++l++L+HpN++ l  vf ++++++++l ++y+e+     dL+
   mKIAA1028   111 -----EIALLRELKHPNVIALQKVFLShsDRKVWLLFDYAEH-----DLW 150  

                   dyls..e..trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPe
                   ++++ ++ +  +k+p+ ++   +k+ ++Qil g+ YLH+n+++HRDLKP+
   mKIAA1028   151 HIIKfhRasKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPA 200  

                   NILldengvvdaflKiaDFGlAkkls..t.sss.lttfvGTpwYmAPEvl
                   NIL+  +g    ++KiaD G+A+++++++++  +l+ +v+T wY+APE+l
   mKIAA1028   201 NILVMGEGPERGRVKIADMGFARLFNspLkPLAdLDPVVVTFWYRAPELL 250  

                   lggngygtkvDvWSlGvilyelltGk.............pPFsgevqdsl
                   lg+++y++++D+W++G+i++ellt ++  + ++++ +++ PF ++     
   mKIAA1028   251 LGARHYTKAIDIWAIGCIFAELLTSEpifhcrqediktsNPFHHD----- 295  

                   dqlqlirkilgpplefdspewdsisrse.fr.................r.
                    ql +i+ ++g p + d++  + ++ +++++++ ++++  +++  +  ++
   mKIAA1028   296 -QLDRIFSVMGFPADKDWEDIRKMPEYPtLQkdfrrttyansslikymEk 344  

                   l.pnlseeakdLikkcLnkDPskRltaeeilqHPwf<-*
                    +++ ++    L+ k+L++DP+kR+t e++lq+P+f   
   mKIAA1028   345 HkVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYF    380  

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