hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj07295/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1026  ( 808 res)   mfj07295

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
SAM_1    SAM domain (Sterile alpha motif)                75.6      1e-18   2
SAM_2    SAM domain (Sterile alpha motif)                74.0    3.2e-18   3
TolA     TolA protein                                  -154.0       0.52   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
TolA       1/1      31   401 ..     1   448 []  -154.0     0.52
SAM_1      1/2     477   542 ..     1    66 []    32.2  1.2e-05
SAM_2      1/3     476   544 ..     1    72 []    20.2    0.048
SAM_1      2/2     555   619 ..     1    66 []    44.9  1.8e-09
SAM_2      2/3     559   621 ..     1    72 []    16.6      0.3
SAM_2      3/3     642   709 ..     1    72 []    37.5  3.1e-07

Alignments of top-scoring domains:
TolA: domain 1 of 1, from 31 to 401: score -154.0, E = 0.52
                   *->keqndklkrAi...iISvvLHiiLialLilgSldetvepepgGeGg.
                      +e+n+ l+  i++ + S+   +    + +  +     e ++gG Gg+
   mKIAA1026    31    MEDNKQLALRIdgaVQSASQEVTNLRAELTATNRRLAELSGGG-GGp 76   

                   ........gsvidAVmVDpgaVaqQynrlqqQkedaarkekktEPvvEEk
                   +++++  ++ +  AV V  +aVa     +   + +a+             
   mKIAA1026    77 gsgpgaatSASAAAVTVADSAVAT----MENHQHGAQVLL---------- 112  

                   PvePdqeRkkklqrqaeeleqkraaEqerlKeLekerlqaqeaakkqaEe
                        +e+  +lq   ee  + r+  +   K Le+ +     +    a e
   mKIAA1026   113 -----REEVVQLQ---EEVHLLRQMKEMLAKDLEESQGGKCSEVL-SATE 153  

                   arkqaeeqqKqaEEakakqakEaakaKaeAeaaKakeeaerkakeekaaA
                   +r q      q E+  a+ akEa  ++  A+++++k e     k +    
   mKIAA1026   154 LRVQLV----QKEQELAR-AKEA-LQAMKADRKRLKGE-----KTD---- 188  

                   aAakkAEeeakakaAAeAkkkAeaeaAelkkkakarEaaaAeAkkkaeaE
                    ++ +  +     a  e + ++ ++                e   k  ++
   mKIAA1026   189 -LVSQMQQLY---ATLESREEQLRDF-----------IRNYEQHRKESED 223  

                   AkaKaaaeAeaKAkaEkAkAdaeAkaKAeaerkAdeeAAkeKAAAEAakK
                   A    +a A++K   E         +K e  r           A+EA + 
   mKIAA1026   224 A---VKALAKEKDLLE--------REKWELRRQ----------AKEATDH 252  

                   AaaekeraaaaeakrKAAAEkaAaadqeaevdDifGsLssgkNapkqGgg
                   Aaa +  ++ ++   K    + A a+q +        ++ +k  pk  + 
   mKIAA1026   253 AAALRSQLDLKDNRMKELEAELAMAKQSL--------ATLTKDVPKRHSL 294  

                   Ak.GagaasadsGktkksGasGaevdqYagqiksaIqsrlldd..dsyaG
                   A +G+ +     G+        a++   a++ +s  q+ l+  +++  a 
   mKIAA1026   295 AMpGETVLN---GNQE--WVVQADLPLTAAIRQS--QQTLYHShpPHPAD 337  

                   KtCrvrikLapDGtdallisvksegGDpalCqAAlaAv....AktakiPk
                   ++ rv+    +     ++++  +  GD    + + + +++++ +t ++  
   mKIAA1026   338 RQVRVSPCHSRQP--SVISDASAAEGDR---SSTPSDInsprHRTHSLCN 382  

                   pPsddaVYeklKninldfkl<-*
                     +++  ++k    +++  l   
   mKIAA1026   383 G-DSPGPVQKSLHNPIVQSL    401  

SAM_1: domain 1 of 2, from 477 to 542: score 32.2, E = 1.2e-05
                   *->dgwsvesVgeWLe.sigllgqYidnFlaagyidgdtllqlteeDLed
                      ++w   +V+ WLe  + + + Y++   a + ++g+ ll l+ eDLe 
   mKIAA1026   477    SHWKAGTVQAWLEvVMAM-PMYVKAC-AENVKSGKVLLSLSDEDLEL 521  

                   .lGvtllGHrkkIlssIqgLk<-*
                   +lGv +  Hr k+ ++I++++   
   mKIAA1026   522 gLGVCSSLHRRKLRLAIEDYR    542  

SAM_2: domain 1 of 3, from 476 to 544: score 20.2, E = 0.048
                   *->veswslesvaeWLe.siglegqYkdnFsdqgitglellllrlteedL
                      ++ w++ +v++WLe  + + + Y+ +  ++  +g ++l l l+ edL
   mKIAA1026   476    MSHWKAGTVQAWLEvVMAM-PMYVKACAENVKSG-KVL-LSLSDEDL 519  

                   aklalGitsvghRkkilskiqelkqq<-*
                    +l lG+ s  hR+k+  +i++ ++    
   mKIAA1026   520 -ELGLGVCSSLHRRKLRLAIEDYRDA    544  

SAM_1: domain 2 of 2, from 555 to 619: score 44.9, E = 1.8e-09
                   *->dgwsvesVgeWLesigllgqYidnFlaagyidgdtllqlteeDLed.
                      d  + +    WL++igl +qY + F +++++dg++l  l + DLe++
   mKIAA1026   555    DLDHHWVAKAWLNDIGL-SQYSQAF-QNHLVDGRMLNSLMKRDLEKh 599  

                   lGvtllGHrkkIlssIqgLk<-*
                   l+v +  H+  Il++I+ L    
   mKIAA1026   600 LNVSKKFHQVSILLGIELLY    619  

SAM_2: domain 2 of 3, from 559 to 621: score 16.6, E = 0.3
                   *->veswslesvaeWLesiglegqYkdnFsdqgitglellllrlteedLa
                       ++ ++     WL  igl  qY ++F  + ++g ++l   l   dL 
   mKIAA1026   559    HWVAKA-----WLNDIGL-SQYSQAFQNHLVDG-RML-NSLMKRDL- 596  

                   klalGitsvghRkkilskiqelkqq<-*
                   + +l+++++ h+  il +i+ l q    
   mKIAA1026   597 EKHLNVSKKFHQVSILLGIELLYQV    621  

SAM_2: domain 3 of 3, from 642 to 709: score 37.5, E = 3.1e-07
                   *->veswslesvaeWLesiglegqYkdnFsdqgitglelll.lrlteedL
                      +++w++++v  W++ i+l ++Y+dn++  g++g+ l+l++ +++e +
   mKIAA1026   642    PVVWTNQRVLKWVRDIDL-KEYADNLTNSGVHGAVLVLePTFNAEAM 687  

                   aklalGitsvghRkkilskiqelkqq<-*
                   a+ alGi s  h   il+     + +   
   mKIAA1026   688 AT-ALGIPSGKH---ILRRHLAEEMS    709  

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