hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpm/mpm09008/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1021  ( 1196 res)   mpm09008

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N 
--------     -----------                                -----    ------- ---
Hydrolase    haloacid dehalogenase-like hydrolase        17.6      0.013   1
E1-E2_ATPase E1-E2 ATPase                              -111.1      0.022   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
E1-E2_ATPase   1/1     180   451 ..     1   245 []  -111.1    0.022
Hydrolase      1/1     489   930 ..     1   183 []    17.6    0.013

Alignments of top-scoring domains:
E1-E2_ATPase: domain 1 of 1, from 180 to 451: score -111.1, E = 0.022
                   *->villivllnatlefyq...esrAekAleaLkklvpptAtVlRdGgke
                       ++++++++a+ + y++  + +A +A+ +        ++ +  G k+
   mKIAA1021   180    PLFFVITVTAIKQGYEdwlRHKADNAMNQ------CPVHFIQHG-KL 219  

                   eeipaeeLvpGDiVevkpGdrVPADgrvvege..................
                   +   ++ L++GDiV vk+ ++ P D++ +++++ +++ + ++ + +++++
   mKIAA1021   220 VRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNradgtchvttasldgess 269  

                   .................................................s
                   ++++   +++++ +++ + ++ + + + ++++++  +  ++ +  ++ ++
   mKIAA1021   270 hkthyavqdtkgfhteadvdslhatieceqpqpdlykfvgrinvyndlnD 319  

                   tLkVDESaLTGESlPVeKhsdvvtpdnplergnmVfaGTlvvs.Gsltgv
                                 PV +         pl+  n++  G + +++  + gv
   mKIAA1021   320 --------------PVVR---------PLGSENLLLRGATLKNtEKIFGV 346  

                   VtatGddTflgkIakLVeeAqssktPlQrlldkfgkiltpvililavlvf
                   ++ tG++T   k+a   ++ ++ ++  ++ ++ f  ++  + +  a++  
   mKIAA1021   347 AIYTGMET---KMALNYQSKSQKRSAVEKSMNTFLIVYLCILVSKALINT 393  

                   iiwllrnfnaafggswleg...............llyalifavallVaAc
                   ++ +++        ++++ +  +++++++++++ +l a++  +a++V   
   mKIAA1021   394 VLKYVW-----QSEPFRDEpwynekteserqrnlFLRAFTDFLAFMVL-- 436  

                   PegLplvvtvalalGtgrmAkkgaLVKglpAvEt<-*
                         +++v++ ++                vE+   
   mKIAA1021   437 ---FNYIIPVSMYVT----------------VEM    451  

Hydrolase: domain 1 of 1, from 489 to 930: score 17.6, E = 0.013
                   *->ikavvFDkDGTLtdgk...............................
                      +  ++ Dk+GTLt+ +   ++   +++   ++   +++  +++++ +
   mKIAA1021   489    VEYIFTDKTGTLTENNmafkeccieghvyvphvicngqvlpdssgid 535  

                   ..................................................
                     +++++  ++++++   +     ++ + ++++ +++ ++++++++ ++ 
   mKIAA1021   536 midsspgvcgrereelffraiclchtvqvkddhcgddvdgpqkspdaksc 585  

                   ....eppiaeaiveaaaelgl....lpleevekllgrgl.gerilleggl
                      ++ p + a+ve  ++lg +  +l   ++e l ++   + r++l + l
   mKIAA1021   586 vyisSSPDEVALVEGVQRLGFtylrLKDNYMEILNRENDiE-RFELLEVL 634  

                   taell.............................................
                   t + ++++ +   ++++++     ++ +++  ++  +++ +  +++ +++
   mKIAA1021   635 TFDSVrrrmsvivksttgeiylfckgadssifprviegkvdqvrsrvern 684  

                   ..................................................
                     ++ ++     ++ +++  ++  +   + +    +++++  +  +  ++
   mKIAA1021   685 aveglrtlcvaykrlepeqyedacrllqsakvalqdrekklaeayeqiek 734  

                   d.evlglial.dklypgarealkaLkerGikvailTggdr.naealleal
                   d ++lg+ a++d+l + a+++++aL+++Gikv++lTg+  ++a a   a+
   mKIAA1021   735 DlVLLGATAVeDRLQEKAADTIEALQKAGIKVWVLTGDKMeTASATCYAC 784  

                   gla.lfdviidsddvggvgpivvgKPkpeifllalerlgvkpeevg....
                    l++    ++  +  +          + + ++ +l  l + + +++++ +
   mKIAA1021   785 KLFrRSTQLLELTTKK---------LEEQSLHDVLFDLSKTVLRCSgsmt 825  

                   ..................................................
                   +++ ++ +++ ++ +   ++   +   +++++++++++ ++   +  ++ 
   mKIAA1021   826 rdsfsglstdmhdygliidgaalslimkpredgsssgnyrelfleicrnc 875  

                   .........................pe.vlmVGDgvnDapalaaAGvgva
                   +     +  + ++ +  +  + +++   +l++GDg nD+ ++  A+vg+ 
   mKIAA1021   876 savlccrmaplqkaqivklikfskeHPiTLAIGDGANDVSMILEAHVGIG 925  

                   mgngg<-*
                    +      
   mKIAA1021   926 VIGKE    930  

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