hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file: /cdna4/rodent/full/goal/mbg/mbg00096/w3open/interpro/cnk_1/seq.in
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Query: mKIAA1011 ( 1666 res) mbg00096
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
SPEC Spectrin repeats 213.2 2.4e-59 9
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
SPEC 1/9 38 146 .. 1 104 [] 0.1 8.5
SPEC 2/9 358 456 .. 1 104 [] 10.4 0.99
SPEC 3/9 575 675 .. 1 104 [] 4.1 3.7
SPEC 4/9 682 780 .. 1 104 [] 41.4 1.2e-07
SPEC 5/9 787 894 .. 1 104 [] 52.0 7.6e-11
SPEC 6/9 901 1003 .. 1 104 [] 54.8 1.1e-11
SPEC 7/9 1010 1110 .. 1 104 [] 51.2 1.3e-10
SPEC 8/9 1337 1440 .. 1 104 [] 38.4 9.5e-07
SPEC 9/9 1447 1551 .. 1 104 [] 21.9 0.09
Alignments of top-scoring domains:
SPEC: domain 1 of 9, from 38 to 146: score 0.1, E = 8.5
*->qqFlrdadel..eaWleeke...qllssedlgeskDlesveallkkH
q+ +++d l +ea ++ ++ + + s++ +l+++ + + +
mKIAA1011 38 QE-WKACDKLydEATMRTTQltySMEHSKPAV--LSLQALACQVQNL 81
qaleaelaaheervdalnelgeqLieesghpdaeeIeerleeLnerWe..
+al++e ++ e + ++l+e +L ++ ++ a Iee++++ ++rW +
mKIAA1011 82 EALQDEAENGERSWEKLQEVIGRLRAS-CPSMAGIIEEKCQDAHSRWTqv 130
..eLlelaeeRrqkLe<-*
+++L ++++e r +L+
mKIAA1011 131 nqDLADQLQEARGQLQ 146
SPEC: domain 2 of 9, from 358 to 456: score 10.4, E = 0.99
*->qqFlrdadeleaWleekeqllssedlgeskDlesveallkkHqalea
++Fl+ ++ ++ le ++ l s +++ ++l+++ +++k + lea
mKIAA1011 358 EKFLHYCERWIQVLEKIQESL-SVEVA--HSLPALLEQQKTYEILEA 401
elaaheervdalnelgeqLieesghpdaeeIeerleeLnerWeeLlelae
e++++++ da + qL++ ++ + +e +L ++W+ +++
mKIAA1011 402 EVSTNQAVADAYVTQSLQLLDTAEIEKRPEFVSEFSKLSDQWQ--RAARG 449
eRrqkLe<-*
R++k +
mKIAA1011 450 VRQRKCD 456
SPEC: domain 3 of 9, from 575 to 675: score 4.1, E = 3.7
*->qqFlrdadeleaWleekeqllssedlgeskDlesveallkkHqalea
q ++++ l++ l+ + + s ++l+ e++ + + ++ e+
mKIAA1011 575 DQCKKKIKKLKKRLQALK-AQSEDPLP--ELHEALHEEKELIKEVEK 618
elaaheervdalnelgeqLieesghpdaeeIeerleeLnerWeeLlelae
la++ ++++l+ + +L + +d ++e+++ L+++We+L+ +++
mKIAA1011 619 SLANWTHSLKELQTMKADLSQHILAEDVTVLKEQIQLLHRQWEDLCLRVA 668
eRrqkLe<-*
R+q e
mKIAA1011 669 IRKQEIE 675
SPEC: domain 4 of 9, from 682 to 780: score 41.4, E = 1.2e-07
*->qqFlrdadeleaWleeke.qllssedlgeskDlesveallkkHqale
F+++ +el aWl +e+++l++ d+ +e +e+l+k + +
mKIAA1011 682 IVFNEKNKELCAWLVQMEnKVLQTADV---SIEEMIEKLQK---DCM 722
aelaaheervdalnelgeqLieesghpdaeeIeerleeLnerWeeLlela
+e++ e +l+++g+qLi++s+ + a+e+ee+l ++n+rW++L +
mKIAA1011 723 EEISLFTENKLQLKQMGDQLIKASSKAKAAELEEKLSKINDRWQHLFDVI 772
eeRrqkLe<-*
R +kL+
mKIAA1011 773 GSRVKKLK 780
SPEC: domain 5 of 9, from 787 to 894: score 52.0, E = 7.6e-11
*->qqFlrdadeleaWleekeqllssedlgeskDlesveallkkHqalea
qq+ +++ l Wl e ls + ++ D +++++ l ++q+l++
mKIAA1011 787 QQLDKNMSNLRTWLARIESELSKPVVYDVCDNQEIQKRLAEQQDLQR 833
elaaheervdalnelgeqLiee....sghpdaeeIeerleeLnerWeeLl
++++h + v+++ + ++ L+ +++ +++ + ++I++ + L++rW++++
mKIAA1011 834 DIEQHSAGVESVFNICDVLLHDsdacANETECDSIQQTTRSLDRRWRNIC 883
elaeeRrqkLe<-*
+++ eRr k e
mKIAA1011 884 AMSMERRMKIE 894
SPEC: domain 6 of 9, from 901 to 1003: score 54.8, E = 1.1e-11
*->qqFlrdadeleaWleekeqllssedlgeskDlesveallkkHqalea
q+Fl+d +e+Wl+++e+ ++ + + +++++ lk+++a+++
mKIAA1011 901 QKFLDDYSRFEDWLKSAERTAACPNSS-EVLYTNAKEELKRFEAFQR 946
elaaheervdalnelgeqLieesghpdaeeIeerleeLnerWeeLlelae
+ ++ +++ +n++ ++L +e + a ++++ ++e n+rW++L++++
mKIAA1011 947 QIHERLTQLELINKQYRRLARENRTDTASKLKQMVHEGNQRWDNLQKRVT 996
eRrqkLe<-*
+ ++L
mKIAA1011 997 AILRRLR 1003
SPEC: domain 7 of 9, from 1010 to 1110: score 51.2, E = 1.3e-10
*->qqFlrdadeleaWleekeqllssedlgeskDlesveallkkHqalea
++F + ++ Wl+e+ +l+ ++ +++++e++++++ +++
mKIAA1011 1010 EEFEGTRESILVWLTEMDLQLTNVEH---FSESDAEDKMRQLNGFQQ 1053
elaaheervdalnelgeqLieesghpdaeeIeerleeLnerWeeLlelae
e++ + +++d+l+ geqLi++s++ da Ie+ leeL++ +e+ ++
mKIAA1011 1054 EITLNTNKIDQLIVFGEQLIQKSEPLDAVLIEDELEELHRYCQEVFGRVS 1103
eRrqkLe<-*
+ +++L
mKIAA1011 1104 RFHRRLT 1110
SPEC: domain 8 of 9, from 1337 to 1440: score 38.4, E = 9.5e-07
*->qqFlrdadeleaWleeke...qllssedlgeskDlesveallkkHqa
qq+ +d+ + aWl+ +e + ++l+ +++ D++++ k++q+
mKIAA1011 1337 QQLKSDIGSIAAWLGKTEaelEALKLAEPP--SDIQEIALRVKRLQE 1381
leaelaaheervdalnelgeqLieesghpdaeeIeerleeLnerWeeLle
+ + +++++ + ++n ++ + + + p+a e+++rl++L W++++
mKIAA1011 1382 ILKAFDTYKALMVSVNVSHKEYLPS-QSPEATELQNRLHQLSLSWDSVQG 1430
laeeRrqkLe<-*
++ +r L
mKIAA1011 1431 VLDSWRGDLR 1440
SPEC: domain 9 of 9, from 1447 to 1551: score 21.9, E = 0.09
*->qqFlrdadeleaWleeke...qllssedlgeskDlesveallkkHqa
q F++ ++l+ Wl +e+++q + + + D + + + +k + +
mKIAA1011 1447 QDFHQLSQDLLLWLATAEsrrQKAHVTSPE--ADRQVLLECQKDLMR 1491
leaelaaheervdalnelgeqLieesghpdaeeIeerleeLnerWeeLle
le+el a++++v++l e L+ + +++d e ee+++ ++++ ++L+e
mKIAA1011 1492 LEKELVARQPQVSSLREISSSLLVKGQGEDYIEAEEKVHVIEKKLKQLQE 1541
laeeRrqkLe<-*
++++ L+
mKIAA1011 1542 QVAQDLMSLQ 1551
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