hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mph/mph02462/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0992  ( 1081 res)   mph02462

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
IGc2     Immunoglobulin C-2 Type                        193.1    2.6e-53   4
IG       Immunoglobulin                                 187.2    1.5e-51   5

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
IG         1/5       6    59 ..     1    58 []     3.0       96
IGc2       1/4     150   225 ..     1    56 []    53.1  3.6e-11
IG         2/5     144   236 ..     1    58 []    53.6  2.6e-11
IGc2       2/4     711   780 ..     1    56 []    45.5  7.2e-09
IG         3/5     705   791 ..     1    58 []    36.8  2.9e-06
IGc2       3/4     845   913 ..     1    56 []    54.8  1.1e-11
IG         4/5     839   924 ..     1    58 []    46.5  3.4e-09
IGc2       4/4     944  1013 ..     1    56 []    39.8  3.7e-07
IG         5/5     938  1024 ..     1    58 []    47.7  1.5e-09

Alignments of top-scoring domains:
IG: domain 1 of 5, from 6 to 59: score 3.0, E = 96
                   *->pp.vtvkeGesvtLtC.astitWy.LtI.nvtpeDsesgGtYtCaat
                       + +      +v+++C+     +++L+I ++ ++D+   G YtC at
   mKIAA0992     6    KElYNSP---DVQIHCeS--GELHtLVIaEAFEDDT---GRYTCLAT 44   

                   ..sgsasseqgttLtVl<-*
                   ++sgs+s   ++++ ++   
   mKIAA0992    45 npSGSDST--SAEVFIE    59   

IGc2: domain 1 of 4, from 150 to 225: score 53.1, E = 3.6e-11
                   *->leGqsVtLtCpasgdpvpnItWlk.gkplp.................
                       eGq V+L+C+++g+p  +++W+++g++++++++ +  +++++++ +
   mKIAA0992   150    SEGQVVVLECRVRGAPPLQVQWFRqGSEIQdspdfrilqkkprstae 196  

                   ..sgstLtiknvsleDsGlYtCvArNsvg<-*
                   ++   tL i +  +eD+G+ tC+A+N  g   
   mKIAA0992   197 peEICTLVIAESFPEDAGIFTCSATNDYG    225  

IG: domain 2 of 5, from 144 to 236: score 53.6, E = 2.6e-11
                   *->pp.vtvkeGesvtLtC.as.....titWy..................
                       +++ ++eG+ v+L+C++ + ++ +++W+++++  +++++ +  +++
   mKIAA0992   144    LQnTAASEGQVVVLECrVRgapplQVQWFrqgseiqdspdfrilqkk 190  

                   ............LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtV
                   ++++  +    +L+I +  peD+   G++tC at+++gs++s  +++L +
   mKIAA0992   191 prstaepeeictLVIaESFPEDA---GIFTCSATndYGSVTS--TAQLVI 235  

                   l<-*
                   +   
   mKIAA0992   236 T    236  

IGc2: domain 2 of 4, from 711 to 780: score 45.5, E = 7.2e-09
                   *->leGqsVtLtCpasgdpvpnItWlk.gkplp.............sgst
                       eG +Vt+tC+++g+p p I W+k+gk++++++++ + +++ ++  +
   mKIAA0992   711    FEGMPVTFTCRVAGNPKPKIYWFKdGKQISpksdhytiqrdldGTCS 757  

                   LtiknvsleDsGlYtCvArNsvg<-*
                   L+ +  +l+D+G+Yt  A N+ g   
   mKIAA0992   758 LHTTASTLDDDGNYTIMAANPQG    780  

IG: domain 3 of 5, from 705 to 791: score 36.8, E = 2.9e-06
                   *->pp.vtvkeGesvtLtC.as.....titWy..................
                       +++   eG +vt+tC++++++++ i+W++++++ ++++++ + +++
   mKIAA0992   705    LKhYKIFEGMPVTFTCrVAgnpkpKIYWFkdgkqispksdhytiqrd 751  

                   ......LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-*
                    +++ +L+ +  t++D    G+Yt +a ++ g +s+  + +L V+   
   mKIAA0992   752 ldgtcsLHTtASTLDDD---GNYTIMAAnpQGRVSC--TGRLMVQ    791  

IGc2: domain 3 of 4, from 845 to 913: score 54.8, E = 1.1e-11
                   *->leGqsVtLtCpasgdpvpnItWlk.gkplp............sgstL
                      +eG   ++ C++sg p+p+ +W  +gkp+ +++ ++   ++++  +L
   mKIAA0992   845    QEGKLCRMDCKVSGLPTPDLSWQLdGKPIRpdsahkmlvrenGVHSL 891  

                   tiknvsleDsGlYtCvArNsvg<-*
                    i++v+  D+G+YtC+A+N++g   
   mKIAA0992   892 IIEPVTSRDAGIYTCIATNRAG    913  

IG: domain 4 of 5, from 839 to 924: score 46.5, E = 3.4e-09
                   *->pp.vtvkeGesvtLtC.as.....titWy..................
                      p+++tv+eG   ++ C++s+ +++ ++W  ++++ ++++ ++   + 
   mKIAA0992   839    PGdLTVQEGKLCRMDCkVSglptpDLSWQldgkpirpdsahkmlvre 885  

                   .....LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-*
                   ++ ++L+I++vt  D+   G+YtC at+++g+ s   + +L V    
   mKIAA0992   886 ngvhsLIIePVTSRDA---GIYTCIATnrAGQNSF--NLELVVA    924  

IGc2: domain 4 of 4, from 944 to 1013: score 39.8, E = 3.7e-07
                   *->leGqsVtLtCpasgdpvpnItWlk.gkplp.............sgst
                        G +V+L+C++sg p p+I W+k++++l +++++ + ++++++   
   mKIAA0992   944    ADGYPVRLECRVSGVPPPQIFWKKeNESLThstervsmhqdnhGYIC 990  

                   LtiknvsleDsGlYtCvArNsvg<-*
                   L i+ +++eD+G Yt +A N++g   
   mKIAA0992   991 LLIQGATKEDAGWYTVSAKNEAG    1013 

IG: domain 5 of 5, from 938 to 1024: score 47.7, E = 1.5e-09
                   *->pp.vtvkeGesvtLtC.as.....titWy..................
                       +++ v  G +v+L+C++s+ ++++i+W++ + + ++++ + + +++
   mKIAA0992   938    LQnTGVADGYPVRLECrVSgvpppQIFWKkeneslthstervsmhqd 984  

                   ......LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-*
                   +++   L I+++t+eD+   G Yt  a++ +g +s+  +++L V+   
   mKIAA0992   985 nhgyicLLIqGATKEDA---GWYTVSAKneAGIVSC--TARLDVY    1024 

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