hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbp/mbp05185/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0985  ( 684 res)   mbp05185

Scores for sequence family classification (score includes all domains):
Model          Description                              Score    E-value  N 
--------       -----------                              -----    ------- ---
RPH3A_effector Rabphilin-3A effector domain             709.1   2.1e-209   1
C2             C2 domain                                260.4    2.4e-74   2
PHD            PHD-finger                                 6.2      0.074   1
C1_1           Phorbol esters/diacylglycerol binding     -4.9       0.93   1

Parsed for domains:
Model          Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------       ------- ----- -----    ----- -----      -----  -------
C1_1             1/1      89   128 ..     1    55 []    -4.9     0.93
PHD              1/1      96   146 ..     1    51 []     6.2    0.074
RPH3A_effector   1/1       4   275 ..     1   310 []   709.1 2.1e-209
C2               1/2     399   488 ..     1    88 []   138.3  1.4e-37
C2               2/2     557   645 ..     1    88 []   122.1    1e-32

Alignments of top-scoring domains:
C1_1: domain 1 of 1, from 89 to 128: score -4.9, E = 0.93
                   *->HhFvhrwnfkqptfCdhCgellwgslgkqGlkCswCklnvHkrChek
                         v++   ++  +C +Cge+l g lg +++ C++Ck nv   C + 
   mKIAA0985    89    ---VAG---DGVNRCILCGEQL-GMLGSACVVCEDCKKNV---CTK- 124  

                   VppeCgcg<-*
                       Cg     
   mKIAA0985   125 ----CGVE    128  

PHD: domain 1 of 1, from 96 to 146: score 6.2, E = 0.074
                   *->yCsvCgkpdddaggdllqCDgCdrwfHlaClgppleeppegkWlCpe
                      +C +Cg+  +  g   + C++C++ + ++C   + ++ p   WlC+ 
   mKIAA0985    96    RCILCGEQLGMLGSACVVCEDCKKNVCTKCGVETSNNRPHPVWLCKI 142  

                   Ctpk<-*
                   C +    
   mKIAA0985   143 CLEQ    146  

RPH3A_effector: domain 1 of 1, from 4 to 275: score 709.1, E = 2.1e-209
                   *->MaDtvvsstqdkWvcPsDRPLqlalraqLqaGWSVhtGaqARSPTdk
                      M+Dtvv+    +W++P+D+PLq+++++qLqaGWSVh+Gaq    Td+
   mKIAA0985     4    MTDTVVN----RWMYPGDGPLQSNDKEQLQAGWSVHPGAQ----TDR 42   

                   qrktesLtaeEkEvIqkViarAEkleslEQqRIGrLVdRLEtMrknvaGn
                   qrk+e+Lt+eEkE+I++ViarAEk+e +EQ+RIGrLVdRLEtMrknvaG+
   mKIAA0985    43 QRKQEELTDEEKEIINRVIARAEKMEAMEQERIGRLVDRLETMRKNVAGD 92   

                   GVsrCLLCgeeLGlLgSkSYAvvCkDCrKkVCtkNCGVEtsdVNqttgkk
                   GV+rC+LCge+LG+LgS++  vvC+DC+K+VCtk CGVEts+     +++
   mKIAA0985    93 GVNRCILCGEQLGMLGSAC--VVCEDCKKNVCTK-CGVETSN-----NRP 134  

                   epvwLCKICsEqREVLWKrSGAWFYKglPkfvLPlktPqrkddplFrPly
                   +pvwLCKIC+EqREV WKrSGAWF+Kg+Pk+vLP+++P++k++p+ +P++
   mKIAA0985   135 HPVWLCKICLEQREV-WKRSGAWFFKGFPKQVLPQPMPIKKTKPQ-QPAG 182  

                   vpaTeeqplpeessaartParGRvvssDsDsDsDLsssdlEDRraPggak
                   +paT+eqp+pe++++ar+ParG                d+EDRr Pg+++
   mKIAA0985   183 EPATQEQPTPESRHPARAPARG----------------DMEDRRPPGQKP 216  

                   GpkltkapgdSSgsmetprWaSpArmsstlldsegWdlGsetGAGdTsrl
                   Gp+lt+apg++S++++t+r aS+Arms+  +dsegWd+ +++G GdTsr+
   mKIAA0985   217 GPDLTSAPGRGSHGPPTRR-ASEARMSTAARDSEGWDHAHGGGTGDTSRS 265  

                   PnGetllRRetsv<-*
                   P G   lRR++sv   
   mKIAA0985   266 PAG---LRRANSV    275  

C2: domain 1 of 2, from 399 to 488: score 138.3, E = 1.4e-37
                   *->LrVtvieAknLppkDfkngksDPYVkvslggdkkd.qkkkTkvikkt
                      L +t+i+Ak+L+p+D +ng++DPYVk++l++  ++++k +Tk+ ++t
   mKIAA0985   399    LQCTIIRAKGLKPMD-SNGLADPYVKLHLLPGASKsNKLRTKTLRNT 444  

                   lNPvWNEtFtFe.vpppdlqe.tLeieVyDydrfgrddflGevs<-*
                   +NPvWNEt+++++++++d+q++tL+i+V+D+d+fg+++f+Ge++   
   mKIAA0985   445 RNPVWNETLQYHgITEEDMQRkTLRISVCDEDKFGHNEFIGETR    488  

C2: domain 2 of 2, from 557 to 645: score 122.1, E = 1e-32
                   *->LrVtvieAknLppkDfkngksDPYVkvslggdkkd.qkkkTkvikkt
                      L V +i++ +L+++D +ng sDP+Vk++l +d +++ k+kT ++kkt
   mKIAA0985   557    LIVGIIRCVHLAAMD-ANGYSDPFVKLWLKPDMGKkAKHKTQIKKKT 602  

                   lNPvWNEtFtFevpppdlqe.tLeieVyDydrfgrddflGevs<-*
                   lNP++NE+F +++ + dl++++L i+V+Dyd  +++d +G ++   
   mKIAA0985   603 LNPEFNEEFFYDIKHSDLAKkSLDISVWDYDIGKSNDYIGGCQ    645  

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