hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mib/mib04069/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0981  ( 2117 res)   mib04069

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PIPKc    Phosphatidylinositol phosphate kinases         554.2   5.1e-162   1
DEP      Domain found in Dishevelled, Egl-10, and Ple   103.7    2.1e-26   1
FYVE     Protein present in Fab1, YOTB, Vac1, and EEA    74.4    1.4e-17   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
FYVE       1/1     170   239 ..     1    81 []    74.4  1.4e-17
DEP        1/1     385   460 ..     1    90 []   103.7  2.1e-26
PIPKc      1/1    1810  2104 ..     1   438 []   554.2 5.1e-162

Alignments of top-scoring domains:
FYVE: domain 1 of 1, from 170 to 239: score 74.4, E = 1.4e-17
                   *->etaphWvpDeeasnClmnCgkeFtlvtrRrHHCRnCGrifCskCssk
                        + +W+pD+  ++C ++C+++Ft  +rRrHHCR CG+ifCs+C+++
   mKIAA0981   170    DLKQYWMPDSQCKEC-YDCSEKFTT-FRRRHHCRLCGQIFCSRCCNQ 214  

                   kaplpklgkekkngknedftpvRVCdsCyerlsk<-*
                   ++p  ++g+             R C  C         
   mKIAA0981   215 EIPGKFMGYTG---------DLRACTYCRKIALS    239  

DEP: domain 1 of 1, from 385 to 460: score 103.7, E = 2.1e-26
                   *->pesglklddrkyflktypncFtGselVdWLldnlegqsnngptkttf
                      ++sg++++d++y+l+t+pnc +G+elV+WL+ n++            
   mKIAA0981   385    HTSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGH------------ 419  

                   iidreeAvhlgqaLlkeGlihhvndpnkhtFkdsknalYrFtd<-*
                   i++r++A+++gqa+++ +++ +v+ ++++ F+d+ +alYr+ +   
   mKIAA0981   420 IATRAQAIAIGQAMVDGRWLDCVS-HHDQLFRDE-YALYRPLQ    460  

PIPKc: domain 1 of 1, from 1810 to 2104: score 554.2, E = 5.1e-162
                   *->lpsdfkakekikfptpgsgleltPshgsadFkfKdYcPevFRaLRev
                      ++++++ ++++k+ t+++ +el++s+ +a+F+++ Y++ +F+++Rev
   mKIAA0981  1810    QDEVDGGDTQKKQLTNPH-VELQFSDANAKFYCRLYYAGEFHKMREV 1855 

                   LfgidpaDylrSLcrsplLlelssgGKSGSfFylSqDDRFiIKtlsksEi
                   + g ++++++rSL++s++  ++++gGKSG++Fy ++DDRFi+K++++ E+
   mKIAA0981  1856 ILGSSEEEFIRSLSHSSP--WQARGGKSGAAFYATEDDRFILKQMPRLEV 1903 

                   kvllkFApmLpnYyehvvqnpgnTLLpKffGlyrVkvkgstsntgkKirf
                   +++l+FAp+++nY++++vq++++T+L+K++G+yr+++k+s++nt+kK ++
   mKIAA0981  1904 QSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDL 1953 

                   lVMeNLFyselkihrkYDLKGStrgReaskdeaikqkentvLKDlDlvee
                   lVMeNLFy ++k+ +++DLKGS+r+R++++d+ +k+++++vL+D++l+++
   mKIAA0981  1954 LVMENLFY-GRKMAQVFDLKGSLRNRNVKTDT-GKESCDVVLLDENLLKM 2001 

                   iynqpiyvdplakkaLlkqikrDceFLeslkIMDYSLLVGIHdkesgqre
                   ++++p+y+++++k++L+++i+ D +FL+s++I+DYSLLVG++d+++    
   mKIAA0981  2002 VRDNPLYIRSHSKSVLRTSIHSDAHFLSSHLIIDYSLLVGRDDTSN---- 2047 

                   eielepnyssdeesssessaslkqektassspdrsstamyscvpsrdSve
                                                                     
   mKIAA0981     - -------------------------------------------------- -    

                   sesSvaiqsvtsssarqalvststaseditgellvsdetdidvpfggnip
                                                                     
   mKIAA0981     - -------------------------------------------------- -    

                   arairaerrrverkeiedkeesatkegenEaydvvLylGIIDiLqtYtld
                                                     +L++GIID+++t+t+d
   mKIAA0981  2048 ----------------------------------ELVVGIIDYIRTFTWD 2063 

                   KKLEHavKsighdgGkgktiSvVsPeqYskRFrdFmdkyFl<-*
                   KKLE++vKs+g++gG+gk+++vVsPe+Y++RF+++mdkyFl   
   mKIAA0981  2064 KKLEMVVKSTGILGGQGKMPTVVSPELYRTRFCEAMDKYFL    2104 

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