hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg09869/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0975  ( 1480 res)   mbg09869

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PX       PX domain                                       98.6    1.2e-25   1
LRR_1    Leucine Rich Repeat                             37.2    3.7e-07   3
TolA     TolA protein                                  -147.0       0.26   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PX         1/1      61   165 ..     1   133 []    98.6  1.2e-25
LRR_1      1/3     336   358 ..     1    25 []    12.2       13
LRR_1      2/3     359   380 ..     1    25 []    13.5      5.2
LRR_1      3/3     381   404 ..     1    25 []    15.2      1.6
TolA       1/1     829  1169 ..     1   448 []  -147.0     0.26

Alignments of top-scoring domains:
PX: domain 1 of 1, from 61 to 165: score 98.6, E = 1.2e-25
                   *->dsilivvvvdpetsrkkegskkhtyyvyeittktnkewsVkRRYsdF
                      ++ ++++vv++e      + + +t+yv+++t  +  ew++k+RYsdF
   mKIAA0975    61    EPAKEARVVGSE------LVDTYTVYVIQVTDGNH-EWTIKHRYSDF 100  

                   eeLhekLlrkfpalgrilPplPpKklfgryrkeslemtsvkhssnnfdee
                   ++LhekL  + + +++ l  lPpKk++g                  ++++
   mKIAA0975   101 HDLHEKLVAERK-IDKSL--LPPKKIIGK-----------------NSRS 130  

                   fiekRrkgLeeyLqrllqhPelsnesevvleFLesd<-*
                    +ekR ++Le+yLq ll   + +   +v+++FL+++   
   mKIAA0975   131 LVEKRERDLEVYLQTLLTTFPDVA-PRVLAHFLHFH    165  

LRR_1: domain 1 of 3, from 336 to 358: score 12.2, E = 13
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                       L++LdLs+ N s+  ++ +s +  p   
   mKIAA0975   336    ALTTLDLSH-N-SIC-EIDESVkLIP    358  

LRR_1: domain 2 of 3, from 359 to 380: score 13.5, E = 5.2
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                      ++e+LdLs+ N  l + + + l++l    
   mKIAA0975   359    KIEYLDLSH-N-GL-RVVDN-LqHLY    380  

LRR_1: domain 3 of 3, from 381 to 404: score 15.2, E = 1.6
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                      nL +LdLs+ N +ls slp   l++     
   mKIAA0975   381    NLVHLDLSY-N-KLS-SLPQPiLsNQG    404  

TolA: domain 1 of 1, from 829 to 1169: score -147.0, E = 0.26
                   *->keqndklkrAiiISvvLHiiLialLilgSldetvepepgGeGggsvi
                       ++n+   + + +S vL         l      + p +    +g v 
   mKIAA0975   829    RNRNSFKLSRVPLSTVL---------LDPTRSCTQPRGAF-ADGHVL 865  

                   dAVmVDpgaVaqQynrlqqQkedaarkekktEPvvEEkPvePdqeRkkkl
                   +   V    V+            a                     +k + 
   mKIAA0975   866 E-LLVGYRFVT------------AIFVL---------------PHEKFHF 887  

                   qrqaeeleqkraaEqerlKeLekerlqaqeaakkqaEearkqaeeqqKqa
                    r+  +l++        l+ L+         ak   ++ +k  +     a
   mKIAA0975   888 LRVYNQLRAS-------LQDLKTVVISKNPSAK-PRNQPAKSRA----SA 925  

                   EEakakqakEaakaKaeAeaaKakeeaerkakeekaaAaAakkAEeeaka
                   E++ +   ++a + +a+   a a + ae  a +      A  +A  e   
   mKIAA0975   926 EQRLQETPADAPAPAAVPPTASAPAPAEALAPDL-----APVQAPGEDRG 970  

                   kaAAeAkkkAeaeaAelkkkakarEaaaAeAkkkaeaEAkaKaaaeAeaK
                      AeA + Aea aA        +E a A+A++ a+aEA   aaaeA a 
   mKIAA0975   971 LTSAEAPAAAEAPAA--------AE-APAAAEAPAAAEA--PAAAEAPAA 1009 

                   AkaEkAkAdaeAkaKAeaerkAdeeAAkeKAAAEAakKAaaekeraaaae
                   A+a  A A+a A+a A a       AA++ AAAEA + A+a +   a a 
   mKIAA0975  1010 AEAP-APAEAPAAAEAPA-------AAEAPAAAEAPASAEAPAPNQAPAP 1051 

                   akrKAAAEkaAaadqeaevdDifGsLssgkNapkqGggAkGagaasadsG
                   a   A                     ++g  ap + g A  +++a     
   mKIAA0975  1052 ARGPA--------------------PARGP-APAG-GPAPAEALAQ---- 1075 

                   ktkksGasGaev.dqYag..qiksa.....IqsrlldddsyaGKtCrvri
                            aev+ qY +++ i+s++++++I s l + +s++    r+r 
   mKIAA0975  1076 ---------AEVpAQYPSerLIQSTseenqIPSHLPVCPSLQ-HIARLRG 1115 

                   kLapDGtdallisvksegGDpalCqAAlaAvAktakiPkpPsddaVYekl
                   + + D     ++ v  e     l +  +    +t+ + +    + V    
   mKIAA0975  1116 RAIIDLFHNSIAEVENEELRHLLWSSVVFY--QTPGLEVT---ACVLLSS 1160 

                   Kninldfkl<-*
                   K    ++     
   mKIAA0975  1161 KAVYFILHD    1169 

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