hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg08419/w3open/interpro/cnk_1/seq.in
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query:  mKIAA0973  ( 1202 res)   mbg08419

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    337.3      1e-96   1
PDZ      Domain present in PSD-95, Dlg, and ZO-1/2.      61.9    8.3e-14   1
TyrKc    Tyrosine kinase, catalytic domain              -41.2    1.4e-08   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
S_TKc      1/1      56   329 ..     1   231 []   337.3    1e-96
TyrKc      1/1      56   329 ..     1   280 []   -41.2  1.4e-08
PDZ        1/1     657   737 ..     1    80 []    61.9  8.3e-14

Alignments of top-scoring domains:
S_TKc: domain 1 of 1, from 56 to 329: score 337.3, E = 1e-96
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik..........eril
                      ++ +k++  Ga+G Vyl+r+++t +++A+K+i++++   +++ +++ 
   mKIAA0973    56    FDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINkqnlilrnqiQQAF 102  

                   rEikiLkk.dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrgr
                    E++iL     P++V ++ +fe++ +l++VmEy+eG  Gd  +llk+ g 
   mKIAA0973   103 VERDILTFaENPFVVGMFCSFETrRHLCMVMEYVEG--GDCATLLKNIGA 150  

                   rglrkvlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds..hvK
                         l+ ++ar yf+++++aLeYLH+ gI+HRDLKP+N+L++s +h+K
   mKIAA0973   151 ------LPVeMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSmgHIK 194  

                   laDFGlArql......................ttfvGTpeYmAPEvl...
                   l+DFGl++    + +++  +++ +++ ++  ++ ++GTpeY+APEv+ ++
   mKIAA0973   195 LTDFGLSKMGlmslttnlyeghiekdarefldKQVCGTPEYIAPEVIlrq 244  

                   gYgkpavDiWSlGcilyElltGkpPFp..qldlifkkig...........
                   gYgk +vD+W+ G+ilyE+l+G+ PF +++++++f ++ +++  ++++++
   mKIAA0973   245 GYGK-PVDWWAMGIILYEFLVGCVPFFgdTPEELFGQVIsddilwpegde 293  

                   ..SpeakdLikklLvkdPekRlta.eaLedeldikaHPff<-*
                     + +a  Li+ lL+ +P  Rl+a+ a+e    +k+H ff   
   mKIAA0973   294 alPTDAQLLISSLLQTNPLVRLGAgGAFE----VKQHSFF    329  

TyrKc: domain 1 of 1, from 56 to 329: score -41.2, E = 1.4e-08
                   *->ltlgkkLGeGaFGeVykGtlk...ieVAVKtLkeda......keeFl
                         +k + +Ga+G Vy+ + +++++  A K++++     +++++   
   mKIAA0973    56    FDTIKLISNGAYGAVYLVRHRdtrQRFAMKKINKQNlilrnqIQQAF 102  

                   rEakiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLld
                    E  i++    ++p +V ++    +          l++vmEy+egGd+  
   mKIAA0973   103 VERDILTFA--ENPFVVGMFCSFETR-------RHLCMVMEYVEGGDCAT 143  

                   yLrknrpklslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenkv
                    L++ +  l+++    +        eYL+  ++vHRDL   N L+++ ++
   mKIAA0973   144 LLKNIGA-LPVEMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGH 192  

                   vKIsDFGLsRdlyddDkkGeskdyYrkkggkggktll......PirWmAP
                   +K +DFGLs+ +         +  Y    +k+++  l+++  +     AP
   mKIAA0973   193 IKLTDFGLSKMGLMS----LTTNLYEGHIEKDAREFLdkqvcgTPEYIAP 238  

                   EslkdgkFtskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevleylk
                   E++    +    D W+ G+ L+E +  + +   +      ++ee++ ++ 
   mKIAA0973   239 EVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGD------TPEELFGQVI 282  

                   kGyRlpkPendlpiSsvtCPdelYd.lMlqCWaedPedRPtFsel.....
                   + + l +  +       ++ +   + l+++  + +P  R       + ++
   mKIAA0973   283 SDDILWPEGD-------EALPTDAQlLISSLLQTNPLVRLGAGGAfevkq 325  

                   verl<-*
                   ++++   
   mKIAA0973   326 HSFF    329  

PDZ: domain 1 of 1, from 657 to 737: score 61.9, E = 8.3e-14
                   *->gglGfsivg.............gifvssvvpGspAakaGrkslglLk
                      + +Gf+++  +   ++++  + +++v +v++G+pA  aG      L+
   mKIAA0973   657    KKYGFTLRAirvymgdsdvysvHHIVWHVEEGGPAQEAG------LC 697  

                   vGDvIleVNGetsvegltheeavdllkkaggggvGekvtLtvlRgg<-*
                   +GD I+ VNG ++v g+ h e+v+l+ k+g+     kv +t  + +   
   mKIAA0973   698 AGDLITHVNG-EPVHGMVHPEVVELILKSGN-----KVAVTTTPFE    737  

//