hmmpfam - search a single seq against HMM database HMMER 2.1.1 (Dec 1998) Copyright (C) 1992-1998 Washington University School of Medicine HMMER is freely distributed under the GNU General Public License (GPL). - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /data11/genetics/InterProScan/iprscan/data/smart.HMMs Sequence file: /cdna4/rodent/full/goal/mbg/mbg08685/w3open/interpro/cnk_1/seq.in - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: mKIAA0960 ( 1668 res) mbg08685 Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- TSP1 Thrombospondin type 1 repeats 252.0 4.9e-71 16 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- TSP1 1/16 72 128 .. 1 66 [] 1.3 8 TSP1 2/16 209 259 .. 1 66 [] 69.8 3.4e-16 TSP1 3/16 375 431 .. 1 66 [] 30.5 0.00023 TSP1 4/16 438 522 .. 1 66 [] 3.2 4.9 TSP1 5/16 527 586 .. 1 66 [] 8.9 1.1 TSP1 6/16 649 707 .. 1 66 [] 46.8 2.8e-09 TSP1 7/16 710 781 .. 1 66 [] 5.9 2.4 TSP1 8/16 786 843 .. 1 66 [] 34.5 1.5e-05 TSP1 9/16 921 971 .. 1 66 [] 17.7 0.11 TSP1 10/16 1050 1107 .. 1 66 [] 40.3 2.5e-07 TSP1 11/16 1110 1175 .. 1 66 [] 9.6 0.92 TSP1 12/16 1180 1231 .. 1 66 [] 5.6 2.6 TSP1 13/16 1234 1295 .. 1 66 [] 7.4 1.6 TSP1 14/16 1300 1352 .. 1 66 [] 48.7 7.6e-10 TSP1 15/16 1353 1423 .. 1 66 [] 17.5 0.12 TSP1 16/16 1428 1486 .. 1 66 [] 14.6 0.25 Alignments of top-scoring domains: TSP1: domain 1 of 16, from 72 to 128: score 1.3, E = 8 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg + +++W+ C g CG G g++tR +c ++ + mKIAA0960 72 LWKTGPWGRCMGDDCGPG----GIQTRAV----WCAHVEGWT--TLH 108 epCs......EtrpCntqpnLqpCp<-* +C + +++ ++ C+ +C+ mKIAA0960 109 TNCKqavrpsNQQNCFK-----VCD 128 TSP1: domain 2 of 16, from 209 to 259: score 69.8, E = 3.4e-16 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg +se+s+WS+CS +tCG+G ++RtR + +pp q gg mKIAA0960 209 VSEFSPWSECS-RTCGSG-----LQHRTR-----HVVAPP---QYGG 241 epCs...EtrpCntqpnLqpCp<-* + C++ +E++ C + pC+ mKIAA0960 242 SGCPnltEFQVCQSN----PCE 259 TSP1: domain 3 of 16, from 375 to 431: score 30.5, E = 0.00023 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg +seW eWSpCS +tC + +g+r+RtR+ +p + mKIAA0960 375 VSEWLEWSPCS-KTCHDVTSPTGTRVRTRT----ITQFPI----GSE 412 epCs...EtrpCntqpnLqpCp<-* ++C+ +E++pC q + mKIAA0960 413 KECPaleEKEPCVSQG---DGA 431 TSP1: domain 4 of 16, from 438 to 522: score 3.2, E = 4.9 *->wseWseWSpCSg...............vtCGgGgrtegvrtRtRssl + ++eW++C +++ +++++++ ++++ CGgG v+tR+ + mKIAA0960 438 GWRTTEWTECHVdpllsqqdkrranqtALCGGG-----VQTREIY-- 477 rvccspppprnqnggepCs.........................EtrpCn c+ ++ s+++++++++ +++ +++ +++ ++ t+ C mKIAA0960 478 --CIQ-------TNDNMLShgntqkdkeaskpvdsklctgpvpnTTQLCH 518 tqpnLqpCp<-* + pCp mKIAA0960 519 V-----PCP 522 TSP1: domain 5 of 16, from 527 to 586: score 8.9, E = 1.1 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg +s+Ws W+pC+ + C + +g++ R+R+ +++ + + mKIAA0960 527 VSPWSAWGPCTYENCNDQQGKKGFKLRKRR-ITNEPTGGS----GAT 568 epCs...EtrpCntqpnLqpCp<-* ++C++ E pC+++ C mKIAA0960 569 GNCPhllEAIPCEEP----SCY 586 TSP1: domain 6 of 16, from 649 to 707: score 46.8, E = 2.8e-09 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg s+Ws+WS+CS tC +G teg +tR R +++ ++ + gg mKIAA0960 649 LSAWSSWSSCS-HTC-SGKTTEGKQTRAR-----SILAYAG--EEGG 686 epCs......EtrpCntqpnLqpCp<-* +C++ + +E+r Cn++ pC mKIAA0960 687 IRCPnisalqEVRSCNEH----PCT 707 TSP1: domain 7 of 16, from 710 to 781: score 5.9, E = 2.4 *->wseWseWSpCSg................vtCGgGgrtegvrtRtRss ++++++W++C +++ ++ +++++ +++++C G ++tR+ mKIAA0960 710 HWQTGPWGQCIEdtsvssfnttttwngeASCSVG-----MQTRKVI- 750 lrvccspppprnqnggepCs......EtrpCntqpnLqpCp<-* c++ + + q+g + C+++ +++ +rpC + pC mKIAA0960 751 ---CVRVNVG--QVGPKKCPeslrpeTVRPCLL-----PCR 781 TSP1: domain 8 of 16, from 786 to 843: score 34.5, E = 1.5e-05 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg +++ s+W+pC +C +G ++ ++R+R ++ p ngg mKIAA0960 786 VTPYSDWTPCP-SSCREGDSGARKQSRQR-----VIIQLP---ANGG 823 epCs....EtrpCntqpnLqpCp<-* ++Cs++ E ++C+ +p C+ mKIAA0960 824 KECSdplyEEKACEAPP---TCH 843 TSP1: domain 9 of 16, from 921 to 971: score 17.7, E = 0.11 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg ++Ws S+C g CG vrtR+R + + + ++ mKIAA0960 921 FTSWSKFSSCNG-DCGA------VRTRKR-----AIVGKS----KKK 951 epCs........EtrpCntqpnLqpCp<-* e C +++ + Et+ C C+ mKIAA0960 952 EKCKnshlypliETQYCP-------CD 971 TSP1: domain 10 of 16, from 1050 to 1107: score 40.3, E = 2.5e-07 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg seWs WS CS ++CG+G v++R+ + p ngg mKIAA0960 1050 LSEWSNWSRCS-KSCGSG-----VKVRSK----WLREKPY----NGG 1082 epCs...........EtrpCntqpnLqpCp<-* +pC++ ++ ++ + E+ pC +C mKIAA0960 1083 RPCPkldhvnqaqvyEVVPCHS-----DCN 1107 [output cut off at A = 10 top alignments] //