hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/TIGRFAMs_HMM.LIB
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj05186/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0939  ( 527 res)   mfj05186

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
b_cpa1   b_cpa1: sodium/hydrogen exchanger 3            207.8    1.7e-58   1
a_cpa1   a_cpa1: Na+/H+ antiporter                      -36.7    6.3e-10   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
b_cpa1     1/1      13   522 ..     1   627 []   207.8  1.7e-58
a_cpa1     1/1      11   525 ..     1   541 []   -36.7  6.3e-10

Alignments of top-scoring domains:
b_cpa1: domain 1 of 1, from 13 to 522: score 207.8, E = 1.7e-58
                   *->dyehvqkPyeivLwILLaSLaKigfHLthkvlrvvPESvLLIvyGll
                              +  +  I+L+ L      L+  +l+ +PESv  + +G+l
   mKIAA0939    13    --------FKEAICIILVHL------LIRYRLHFLPESVAVVSLGIL 45   

                   vGgiikaldhHYI...idpptLdsslFFlyLLPPIVLdAGYfmpkreFfe
                   +G +ik      + + +    + + +FFl LLPPI+ ++GY++ k +Ff 
   mKIAA0939    46 MGAVIKVIEFKKLanwKEEEMFRPNMFFLLLLPPIIFESGYSLHKGNFFQ 95   

                   NLgsILlFAvvGTlinAfvlGlsLYgIcliggfgsidIgLLdnLlFGslI
                   N+gsI lFAv GT i+Afv+G+  Y  +l  +  + + +  d + FGslI
   mKIAA0939    96 NIGSITLFAVFGTAISAFVVGGGIY--FLGQADVISKLNMTDSFAFGSLI 143  

                   SAVDPVaVLavFeElhVnekLyilIFGESLLNDAVtvVLYntfekFiklS
                   SAVDPVa  a+F++lhV+++L +l+FGES LNDAV++VL nt e  +   
   mKIAA0939   144 SAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNTAEGLTRK- 192  

                   DasdeavtivdvveGcvsfFv.vtlGvGlLvGVvfGflvafitrfTkhir
                    +   +v +   +   ++ F+++ +G +   G + G ++a+++++   ++
   mKIAA0939   193 -H-MSDVSGWQTFSQALGYFLkMFFG-SAALGTLTGLISALVLKHIDLRK 239  

                   YPvIEPlfvllisYlSYLlAEtlhlSGILAlifCGitmkkYveaNiSreS
                    P  E ++   ++Yl Y lAE+ +lSGI+A++f+Gi+m++Y   N S   
   mKIAA0939   240 TPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVT 289  

                   etTikYfmKmlsSlSEtlIFifLGvSlVsenhewnwplaFvvvTlvfCvA
                   ++    ++++ + l Et+ F fLG+S +s  h +     Fv+  +v  + 
   mKIAA0939   290 QILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEI--SFVIWCIVLVL- 336  

                   RWCAVFPLSQFVNWiYRvlgvltLswilNeFrSvkvelpfkDQlvifyaG
                                   R+  ++ Ls+ lN Fr    ++++k  +++ ++G
   mKIAA0939   337 --------------FGRAVNIFPLSYLLNFFR--DHKITPKMMFIMWFSG 370  

                   lRGAVafaLallldekifpaKklFvtTtLvVvffTVIfQGlTIkplvevL
                   lRGA+ +aL l l +   +   l  tTt+v+v fT  + G+ + pl+++ 
   mKIAA0939   371 LRGAIPYALSLHLGLEPMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLV 420  

                   kvkkddkskekinEelhlrllDHllpgIEDicGqygHdklidKlnkfdkk
                   ++     ++++ ++          +                         
   mKIAA0939   421 DIEDARARRRSKKD---------VN------------------------- 436  

                   ylkkvlirrnspkssikivavyhklnlkqaIslveeGerrkllsfvgtnS
                    l+k +  +n+  s    ++   + +   +   +        l +  +  
   mKIAA0939   437 -LSKTEKMGNAIES--EHLSELTEEEYEAHYIRQQDLKGFMWLDAKYL-- 481  

                   tdNivnvDFstPepsnsepivsYFLREnvsAvglpalSsedkeeeiRdtE
                                p  +++                  ++   +  +    
   mKIAA0939   482 ------------NPFFTRRL--------------TQEDLHHGRIQMKS-- 503  

                   DmvtHHiLstnlykprQrlqsrYsrhvLkpvpnE<-*
                          L++  y  +    s          +++   
   mKIAA0939   504 -------LTNKWYEEVRQGPS--------GSEDD    522  

a_cpa1: domain 1 of 1, from 11 to 525: score -36.7, E = 6.3e-10
                   *->Vvive.LvvavsavvvlvkryrvPlpvllilaGaLlG..........
                      V + e + + ++   ++ +   +P  v+ +  G L+G   +  + ++
   mKIAA0939    11    VCFKEaICIILVHLLIRYRLHFLPESVAVVSLGILMGavikviefkk 57   

                   LagllleVeldrEvvLlLFLPpLLFeeamntdlrElrenlReIvllAlal
                   La    e  + +  ++lL LPp+ Fe +       +  n + I l+A  +
   mKIAA0939    58 LANWKEEEMFRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFG 107  

                   VVvTvvaVgFslrWvvLG.......iplalAlvLGAvlSpTDAvAvaglv
                     + + +Vg  ++   LG+ +  +++     +++G  +S+ D+vA  +++
   mKIAA0939   108 TAISAFVVGGGIY--FLGqadviskLNMTDSFAFGSLISAVDPVATIAIF 155  

                   keirlPkkllivLeGESllNDGaALVvfavAvavalGkavfdpaa.....
                       +   l  ++ GES+lND+  +V+   A      k   d+ + ++ +
   mKIAA0939   156 NALHVDPVLNMLVFGESILNDAVSIVLTNTAEGLTR-KHMSDVSGwqtfs 204  

                   .avveFvvvavGGilaGLvVgyLvtRsLRFLlRakiD...eplveialll
                   +a + F +   G ++ G + g         +l   iD ++ p  e  + +
   mKIAA0939   205 qALGYFLKMFFGSAALGTLTGLISA----LVL-KHIDlrkTPSLEFGMMI 249  

                   lapFaaFlLAerlkvSGVvAvvaAGLvLtrvGrdfsisaasRlraldfWs
                   + +++ + LAe +  SG+ A++ +G+v+  +      s+ + + +  +  
   mKIAA0939   250 IFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHH-NLSPVTQILMQQTLR 298  

                   vlvFlvNgivFvLvGvqlpgiiesalkeaevapaaviLalavtavviyav
                    + Fl    vF ++G+ +    +    e+   +   +L l+  av i + 
   mKIAA0939   299 TVAFLCETCVFAFLGLSIFS--FPHKFEISFVIWCIVLVLFGRAVNIFPL 346  

                   layvrfGWltvlkkfvnRvLKKktrevGsWtfreklVvswAGlRGaislA
                     +  f        f +    K t  +         +  + GlRGai+ A
   mKIAA0939   347 SYLLNF--------FRD---HKITPKMM-------FIMWFSGLRGAIPYA 378  

                   aaLSvPllllsgaaFPdRyllvFlvavViLfslLvqgvsLpilvkrkeva
                   + L  +l      +   R l+     v++Lf++L+ g s   l++   + 
   mKIAA0939   379 LSLHLGLE-----PMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLVDIE 423  

                   edserekEeriARaiaAraAlvaLqkvverlaADvvedvakeLlkelder
                   +          ARa+      v L k +  + A   e +    + e+++ 
   mKIAA0939   424 D----------ARARRRSKKDVNLSKTEKMGNAIESEHLSELTEEEYEAH 463  

                   vvenLRlrAdgeekveSdlaeknD.LerrvrlavLdakrsavvdlratrl
                    +       d++     d    n    rr     L + r  +  l  t+ 
   mKIAA0939   464 YIR----QQDLKGFMWLDAKYLNPfFTRRLTQEDLHHGRIQMKSL--TNK 507  

                   isdevlreLlreLDlkeaeLle<-*
                     +ev +      D +     e   
   mKIAA0939   508 WYEEVRQGPSGSEDDEQ----E    525  

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