hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpm/mpm06003/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0928  ( 1475 res)   mpm06003

Scores for sequence family classification (score includes all domains):
Model          Description                              Score    E-value  N 
--------       -----------                              -----    ------- ---
Ribonuclease_3 RNase3 domain                            228.0    1.4e-64   2
DUF283         Domain of unknown function               212.1    8.4e-60   1
PAZ            PAZ domain                               151.6    1.4e-41   1
Helicase_C     Helicase conserved C-terminal domain      62.1    1.2e-14   1
dsrm           Double-stranded RNA binding motif         41.3    2.2e-08   1

Parsed for domains:
Model          Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------       ------- ----- -----    ----- -----      -----  -------
Helicase_C       1/1      29   115 ..     1    76 []    62.1  1.2e-14
DUF283           1/1     189   281 ..     1    99 []   212.1  8.4e-60
PAZ              1/1     450   624 ..     1   160 []   151.6  1.4e-41
Ribonuclease_3   1/2     872  1130 ..     1    93 []    94.1  2.9e-24
Ribonuclease_3   2/2    1255  1377 ..     1    93 []   133.7  3.3e-36
dsrm             1/1    1403  1465 ..     1    74 []    41.3  2.2e-08

Alignments of top-scoring domains:
Helicase_C: domain 1 of 1, from 29 to 115: score 62.1, E = 1.2e-14
                   *->ll.epgikvarlhG...........glsqeeReeilekFrsgkskvL
                      +l +   +++  hG +++++++++ + + +++ee+l+kFr+ ++++L
   mKIAA0928    29    ELaYISSNFITGHGigknqprskqmEAEFRKQEEVLRKFRAHETNLL 75   

                   vaTdvaarGlDipdvnlVInydlpwnpesyiQRiGRaGRaG<-*
                   +aT+v ++G+Dip +nlV+ +dlp  + sy+Q  GR +Ra    
   mKIAA0928    76 IATSVVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGR-ARAP    115  

DUF283: domain 1 of 1, from 189 to 281: score 212.1, E = 8.4e-60
                   *->AvglvnkYCsrLPsDvfTrLvPeftiekqelpggGvTeYcfeLeLPi
                      A+g++n+YC+rLPsD+fT+L+P++  +++elp+g   +++++L+LPi
   mKIAA0928   189    AIGHINRYCARLPSDPFTHLAPKC--RTRELPDG---TFYSTLYLPI 230  

                   NsPlkaaiVLGpPmssirlAqqavALiaCkkLHrmGeLDDhLlPlgkegv
                   NsPl+a+iV GpPm s+rlA+++vALi+C+kLH++GeLD hL+P+gke+v
   mKIAA0928   231 NSPLRASIV-GPPMDSVRLAERVVALICCEKLHKIGELDEHLMPVGKETV 279  

                   ka<-*
                   k+   
   mKIAA0928   280 KY    281  

PAZ: domain 1 of 1, from 450 to 624: score 151.6, E = 1.4e-41
                   *->qpvldfltdiltqrtrlgsdfqeeerm....fikkaLkGliVlttyn
                      +  ++f++di++ + r+g+ +++++++++  f  +++++++++++y+
   mKIAA0928   450    DIDFKFMEDIEKSEARIGIPSTKYSKEtpfvFKLEDYQDAVIIPRYR 496  

                   nnkqpkerrtYrIdgisfdptpnstFplkrddeegegdgkeisvaeYyke
                   n +qp    +++++++ +d tp+s+Fp            ++ ++aeYyk 
   mKIAA0928   497 NFDQP---HRFYVADVYTDLTPLSKFPSP----------EYETFAEYYKT 533  

                   kYnielkypnlPllvvgkkkrrlnlgtpre....................
                   kYn++l+  n+Pll+v++++ rlnl+tpr+ +++++  + ++ ++++ + 
   mKIAA0928   534 KYNLDLTNLNQPLLDVDHTSSRLNLLTPRHlnqkgkalplssaekrkakw 583  

                   ....qpnyLPpELCfitggqrymrkdfnlqksiaiktrasp<-*
                   ++ +++++L+pELC i+++++++++++++++si+++ +++    
   mKIAA0928   584 eslqNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLL    624  

Ribonuclease_3: domain 1 of 2, from 872 to 1130: score 94.1, E = 2.9e-24
                   *->ERLEFLGDaVLnlvvseyLykkkfPdlsEGeLsklRaalVsnetLak
                      ERLE LGD++L+ +++ yL+ +++Pd++EG Ls +R++ Vsn +L++
   mKIAA0928   872    ERLEMLGDSFLKHAITTYLF-CTYPDAHEGRLSYMRSKKVSNCNLYR 917  

                   lArklgLgkylwllgkgelks.............................
                   l++k+gL++ +   + + +   +  +++   +++++++++ ++++ +++ 
   mKIAA0928   918 LGKKKGLPSRM-VVSIFDP-Pvnwlppgyvvnqdksnsekwekdemtkdc 965  

                   ..................................................
                      +++ ++  +++++ + + ++++ +++++  + ++++ +  ++   + 
   mKIAA0928   966 llangklgeaceeeedltwrapkeeaededdfleydqehiqfidsmlmgl 1015 

                   ..................................................
                   +   ++ + ++ + +++  + + +++ + ++ +  ++ ++ + ++ +   
   mKIAA0928  1016 gafvrkislspfsasdsayewkmpkkaslgsmpfasgledfdysswdamc 1065 

                   ........................................ggrerpkiLA
                     ++++  ++++   +  ++++++ + ++++++ + + ++ + + +k +A
   mKIAA0928  1066 yldpskaveeddfvvgfwnpseencgvdtgkqsisydlhtEQCIADKSIA 1115 

                   DvfEAliGAiYLDgG<-*
                   D++EAl+G ++ ++G   
   mKIAA0928  1116 DCVEALLGCYLTSCG    1130 

Ribonuclease_3: domain 2 of 2, from 1255 to 1377: score 133.7, E = 3.3e-36
                   *->ERLEFLGDaVLnlvvseyLykkkfPdlsEGeLsklRaalVsnetLak
                      +RLEFLGDa+L+++++++Ly +   ++s+G L++lR+alV+n  +a+
   mKIAA0928  1255    QRLEFLGDAILDYLITKHLY-EDPRQHSPGVLTDLRSALVNNTIFAS 1300 

                   lArklgLgkylwllgkgelks.............................
                   lA+k++ +ky+ ++ ++el++  ++  + + ++++ ++ +++ +++++++
   mKIAA0928  1301 LAVKYDYHKYF-KAVSPELFHviddfvkfqleknemqgmdselrrseede 1349 

                   ...ggrerpkiLADvfEAliGAiYLDgG<-*
                   +++   e+pk+++D+fE+l+GAiY+D+G   
   mKIAA0928  1350 ekeEDIEVPKAMGDIFESLAGAIYMDSG    1377 

dsrm: domain 1 of 1, from 1403 to 1465: score 41.3, E = 2.2e-08
                   *->pksaLqElaqkrklplpeYelvkeeGptPaHaprFtvevkvggktyv
                      p s++ El++++   +  +   +++    +++ r tvev+ +gk   
   mKIAA0928  1403    PRSPVRELLEMEPE-TAKFSPAERTY---DGKVRVTVEVVGKGK--- 1442 

                   rktfgeGsGsSKKeAkqaAAeaALekL<-*
                       ++G+G+S+++Ak aAA++AL++L   
   mKIAA0928  1443 ----FKGVGRSYRIAKSAAARRALRSL    1465 

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