hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mpg/mpg00351/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0904  ( 1051 res)   mpg00351

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    332.0    3.9e-95   1
TyrKc    Tyrosine kinase, catalytic domain               19.7    2.3e-12   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
S_TKc      1/1     299   592 ..     1   231 []   332.0  3.9e-95
TyrKc      1/1     299   592 ..     1   280 []    19.7  2.3e-12

Alignments of top-scoring domains:
S_TKc: domain 1 of 1, from 299 to 592: score 332.0, E = 3.9e-95
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik.........erilr
                      ++++ ++G+G++G+Vy+a+dk+tg+lvA+K+++ ++++++ +++++r
   mKIAA0904   299    FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRldnekegfpITAIR 345  

                   EikiLkk.dHPNIVkLydvfed...........dklylVmEyceGdlGdL
                   EikiL++  H  +V+++++  d+++  + +++++ +ylV+Ey+++   dL
   mKIAA0904   346 EIKILRQlVHQSVVNMKEIVTDkqdaldfkkdkGAFYLVFEYMDH---DL 392  

                   fdllkkrgrrglrkvlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNi
                   + ll++   +     +sE++++++++Q+ ++L+Y+H+++++HRD+K +Ni
   mKIAA0904   393 MGLLESGLVH-----FSEdHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNI 437  

                   LLds..hvKlaDFGlArql........ttfvGTpeYmAPEvl....gYgk
                   LL++++++KlaDFGlAr+++++++++ t  v T++Y++PE+l +++ Y++
   mKIAA0904   438 LLNNsgQIKLADFGLARLYnseesrpyTNKVITLWYRPPELLlgeeRYTP 487  

                   pavDiWSlGcilyElltGkpPFp......qldlifkkig...........
                    a+D+WS+Gcil El+t kp F+ + +  ql+li +++g++ +  +++  
   mKIAA0904   488 -AIDVWSCGCILGELFTKKPIFQanlelaQLELISRLCGspcpavwpdvi 536  

                   .........................SpeakdLikklLvkdPekRlta.ea
                   + ++ ++ ++++ ++++ +++ +  ++ a+dL++++L+ dP+kR ta++ 
   mKIAA0904   537 klpyfntmkpkkqyrrrlreefsfiPSAALDLLDHMLTLDPSKRCTAeQT 586  

                   LedeldikaHPff<-*
                   L+         f+   
   mKIAA0904   587 LQ-------SDFL    592  

TyrKc: domain 1 of 1, from 299 to 592: score 19.7, E = 2.3e-12
                   *->ltlgkkLGeGaFGeVykGtlk...ieVAVKtLkeda.....keeFlr
                         + ++GeG +G+Vyk++ k++++ VA K+++ d ++++     +r
   mKIAA0904   299    FDIIGIIGEGTYGQVYKAKDKdtgELVALKKVRLDNekegfPITAIR 345  

                   EakiMkklGgkHpNiVkLlGvcteegrr..F.mevePlmivmEymegGdL
                   E+ki+++l   H+ +V++  ++t+++   +F+   +  ++v+Eym++ dL
   mKIAA0904   346 EIKILRQL--VHQSVVNMKEIVTDKQDAldFkKDKGAFYLVFEYMDH-DL 392  

                   ldyLrknrpklslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgen
                      L +   ++s ++  sf+ Q  +G +Y ++knf HRD+ + N+L+++ 
   mKIAA0904   393 MGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNS 442  

                   kvvKIsDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWmAPEsl.
                   +++K +DFGL+R   ++    es  y       ++   + +   +PE l 
   mKIAA0904   443 GQIKLADFGLARLYNSE----ESRPYT------NKV--ITLWYRPPELLl 480  

                   kdgkFtskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevleylkkGy
                    + ++t++ DVWS G  L E+ft       +     ++ +++    +   
   mKIAA0904   481 GEERYTPAIDVWSCGCILGELFTKKPIFQAN-----LELAQLELISRLC- 524  

                   RlpkPendlpiS.........................svtCPdelYdlMl
                     p+P+      ++  + +  ++ +++++ +++ ++++   P++  dl  
   mKIAA0904   525 GSPCPAV----WpdviklpyfntmkpkkqyrrrlreeFSFIPSAALDLLD 570  

                   qCWaedPedRPtFsel..verl<-*
                        dP++R+t ++  + ++l   
   mKIAA0904   571 HMLTLDPSKRCTAEQTlqSDFL    592  

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