hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/meh/meh02302/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0897  ( 1140 res)   meh02302

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
SAM_1    SAM domain (Sterile alpha motif)                73.4    4.7e-18   2
SAM_2    SAM domain (Sterile alpha motif)                69.8    5.8e-17   3
GBP_C    Guanylate-binding protein, C-terminal domain  -142.4       0.18   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
GBP_C      1/1     234   435 ..     1   305 []  -142.4     0.18
SAM_1      1/2     792   858 ..     1    66 []    16.9   0.0086
SAM_2      1/3     791   860 ..     1    72 []    13.0     0.68
SAM_1      2/2     898   962 ..     1    66 []    56.6  5.3e-13
SAM_2      2/3     901   964 ..     1    72 []    15.1     0.43
SAM_2      3/3     985  1057 ..     1    72 []    43.1  6.4e-09

Alignments of top-scoring domains:
GBP_C: domain 1 of 1, from 234 to 435: score -142.4, E = 0.18
                   *->GGiiVTGprLatLVqtYvnAInSGsVPCl.esavtTLAQiENsaAVq
                              rL tL         S +V  l+e++  +LAQ E      
   mKIAA0897   234    --------RLVTL---------SATVTELeEDLREALAQKE------ 257  

                   kAiahYeeqMeQrleLPTetlQeLLdvHrdCEkEAlavFmenSFkNVDvk
                            Me r+ +       L     ++ +EA       S+   D +
   mKIAA0897   258 --------DMEERITTLEKR--YL-----AAQREA------TSIH--DLN 284  

                   QkFqrkLvaqLeaakedFcrkNeeaSssrCqalLedLskdLeelikqGdf
                    k   +L     a ke   r+ ee +       L++L +  e++++q   
   mKIAA0897   285 DKLENEL-----ANKESLHRQCEEKARH-----LQELLEVAEQKLQQ--- 321  

                   svpGGhrLfleavqeieakYkQvPrKGvkAsevLkefLqDILVHskedla
                       + ++  e + e+ea+  Q+     kA+e            ++++++
   mKIAA0897   322 ---TMRKA--ETLPEVEAELSQRIAALTKAEE------------RHGNIE 354  

                   DsLlqtdqaLtlkekaiEaerNikkEaAEkaekllrEkQKrhEeamEakE
                     L q + +L++k + ++  r                          ++E
   mKIAA0897   355 EHLRQLEGQLEEKNQELARVR--------------------------QRE 378  

                   ksyqEhkkqLtekmEserkqLmaEqnrmLEhklkeqeeLleeGFk..nes
                   k ++ h k+L          L+ E n  L ++lke+ ++lee+ + ++e 
   mKIAA0897   379 KMNEDHNKRLS----DTVDRLLSESNERLQLHLKERMAALEEKGRlsEEI 424  

                   tllekeIselr<-*
                   + l++e+ +l+   
   mKIAA0897   425 EKLRQEVDQLK    435  

SAM_1: domain 1 of 2, from 792 to 858: score 16.9, E = 0.0086
                   *->dgwsvesVgeWLe.sigllgq.YidnFlaagyidgdtllqlteeDLe
                       +w+  +V  WLe   g+ +  Y+    +a+ ++g  +  l+  +++
   mKIAA0897   792    AQWDGPTVVSWLElWVGM-PAwYVAAC-RANVKSGAIMSALSDTEIQ 836  

                   d.lGvtllGHrkkIlssIqgLk<-*
                   +++G+ ++ Hr+k+ ++Iq +    
   mKIAA0897   837 ReIGISNALHRLKLRLAIQEMV    858  

SAM_2: domain 1 of 3, from 791 to 860: score 13.0, E = 0.68
                   *->veswslesvaeWLe.siglegqYkdnFsdqgitglellllrlteedL
                        +w+ ++v +WLe  +g+ +    +  ++++ ++ ++   l+  + 
   mKIAA0897   791    FAQWDGPTVVSWLElWVGM-PAWYVAACRANVKSGAIM-SALSDTEI 835  

                   aklalGitsvghRkkilskiqelkqq<-*
                    + ++Gi+++ hR+k+  +iqe+      
   mKIAA0897   836 -QREIGISNALHRLKLRLAIQEMVSL    860  

SAM_1: domain 2 of 2, from 898 to 962: score 56.6, E = 5.3e-13
                   *->dgwsvesVgeWLesigllgqYidnFlaagyidgdtllqlteeDLed.
                      d ++ +   eWL s+gl +qY++ F +  ++d ++l +lt+ DL+ +
   mKIAA0897   898    DMNHEWIGNEWLPSLGL-PQYRSYF-MECLVDARMLDHLTKKDLRVh 942  

                   lGvtllGHrkkIlssIqgLk<-*
                   l+++   Hr  ++++I  Lk   
   mKIAA0897   943 LKMVDSFHRTSLQYGIMCLK    962  

SAM_2: domain 2 of 3, from 901 to 964: score 15.1, E = 0.43
                   *->veswslesvaeWLesiglegqYkdnFsdqgitglellllrlteedLa
                       e   +    eWL s+gl +qY+ +F+++ ++  ++l  +lt  dL 
   mKIAA0897   901    HEWIGN----EWLPSLGL-PQYRSYFMECLVDA-RML-DHLTKKDL- 939  

                   klalGitsvghRkkilskiqelkqq<-*
                     +l++ +  hR  +  +i +lk     
   mKIAA0897   940 RVHLKMVDSFHRTSLQYGIMCLKRL    964  

SAM_2: domain 3 of 3, from 985 to 1057: score 43.1, E = 6.4e-09
                   *->veswslesvaeWLesiglegqYkdnFsdqgitglelll.lrlteedL
                      v +w++++v +W++sigl ++Y+ n+ + g++g+ l l++++++++L
   mKIAA0897   985    VLVWTNDQVVHWVQSIGL-RDYAGNLHESGVHGALLALdENFDHNTL 1030 

                   a.klalGitsvghRkkilskiqelkqq<-*
                   a  l+++ +s++ R+ + +++++l+     
   mKIAA0897  1031 AlVLQIPTQSTQARQVMEREFNNLLAL    1057 

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