hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg06494/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0890  ( 1057 res)   mbg06494

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N 
--------   -----------                                  -----    ------- ---
DUF1605    Domain of unknown function (DUF1605)          69.8    5.8e-17   1
HA2        Helicase associated domain (HA2)              64.0    3.1e-15   1
DEAD       DEAD/DEAH box helicase                        24.4    2.1e-06   1
dsrm       Double-stranded RNA binding motif             12.7      0.039   1
Helicase_C Helicase conserved C-terminal domain          11.3      0.022   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
dsrm         1/1      78   146 ..     1    74 []    12.7    0.039
DEAD         1/1     469   624 ..     1   266 []    24.4  2.1e-06
Helicase_C   1/1     695   772 ..     1    76 []    11.3    0.022
HA2          1/1     763   856 ..     1   124 []    64.0  3.1e-15
DUF1605      1/1     900  1054 ..     1   140 []    69.8  5.8e-17

Alignments of top-scoring domains:
dsrm: domain 1 of 1, from 78 to 146: score 12.7, E = 0.039
                   *->pksaLqElaqkrklp.....lpeYelvkeeGptPaHaprFtvevkvg
                      pk++L+    +  + ++ ++ ++Y ++  +G   +++++ t + k  
   mKIAA0890    78    PKNLLNSVIGRALGIshakdKLVYVHT--NG---PKKKKVTLHIKWP 119  

                   gktyvrktfgeGsGsSKKeAkqaAAeaALekL<-*
                     +       eG Gs K +A+++AA+aA++ +   
   mKIAA0890   120 KSV-----EVEGYGSKKIDAERQAAAAACQLF    146  

DEAD: domain 1 of 1, from 469 to 624: score 24.4, E = 2.1e-06
                RF    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   *->ptpiQaeaipaileneGfalredvlssggmdrlvlqApTGSGKTlaf
                      +++i           e    +  v+        v++++TG GKT+  
   mKIAA0890   469    LSAI-----------EQ---H-PVV--------VISGDTGCGKTTRI 492  

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   llPilygqrllkgpksarggksqgggknergfkidspqalvlaPTreLae
                      +l  +r   +   ar                    +++  P+r  a 
   mKIAA0890   493 PQLLL--ERYVTEGRGAR------------------CNVIITQPRRISAV 522  

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   QiyeelkkllkilalsplgvnellrrigtglrvavlslyGGsslkdqldk
                    ++++++                 +++g+ lr  v        + + + k
   mKIAA0890   523 SVAQRVS-----------------HELGPSLRRNVG------FQVRLESK 549  

                RF x xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxx
                   l.rgkreskggpdIvvgTPgrLldllrngrinikievssertgkl.klkn
                    + +      g  ++ +T g Ll+ l                ++ ++l+ 
   mKIAA0890   550 PpAR------GGALLFCTVGILLRKL----------------QSNpSLEG 577  

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   lkhlkllVlDEahrlldmghgFgedleeilrrlprneplraqllgtilHq
                   +   + +++DE+h+      +F   l + l+rl++               
   mKIAA0890   578 V---SHVIVDEVHERDV-NTDFLLILLKGLQRLNP---AL---------- 610  

                RF xxxxxxxxxxxxxxxxxxxxx   
                   kpniQtllfSATlpprevedl<-*
                       +++l+SAT      e++   
   mKIAA0890   611 ----RLVLMSATG-DN--ERF    624  

Helicase_C: domain 1 of 1, from 695 to 772: score 11.3, E = 0.022
                   *->ll.epgikvarlhGglsqeeReeilekFrsgkskvLvaTdvaarGlD
                       + +p     ++h++++  ++++i+++   g +k+++aT++a+++++
   mKIAA0890   695    GCfLP-----PVHSNIPMMDQKAIFQQPPLGVRKIVLATNIAETSIT 736  

                   ipdvnlVInydl.............pwnpesyiQRiGRaGRaG<-*
                   + d+ +V++ +l+++++ + +++  p + +++ +        G   
   mKIAA0890   737 VNDIVHVVDSGLhkeerydlktkvaPLSWAQLTH-------WG    772  

HA2: domain 1 of 1, from 763 to 856: score 64.0, E = 3.1e-15
                   *->aAlelLy...eLgAlrDsdgeLTsplGrlmarlPldPrLgkmLvlla
                       +++ L++ + +g+l D+ + LT  lG+++a++ +dPrL+k++ +la
   mKIAA0890   763    LSWAQLThwgMIGVL-DQREYLT-TLGQRLAHISTDPRLAKAI-VLA 806  

                   alfgcldealiiaaiLsvrgspfvntGvDRdaqrlpldksekakrWNiSr
                   a+f+cl++ l+++++L+  ++pf +          +l  + +a+     +
   mKIAA0890   807 AIFRCLHPLLVVVSCLT--RDPFSS----------SL--QNRAE-----V 837  

                   dlarakfegrsleksarsrlts.lsDhlall<-*
                   d ++a +            +  + sDhla++   
   mKIAA0890   838 DKVKALL------------SHDsGSDHLAFV    856  

DUF1605: domain 1 of 1, from 900 to 1054: score 69.8, E = 5.8e-17
                   *->kQLlrilkrlglp............lnsssgdiellrkailaGlypN
                      kQ+++ +++++l++++++ + ++ ++n+ s+++el++ +++aGlypN
   mKIAA0890   900    KQFSENIYEAFLVgkpsdctlpsaqCNEYSEEEELVKGVLMAGLYPN 946  

                   vArresdrggkgsYktlrsvrlpv.r.kk.a.nisd.v.kdgeekgfktn
                   + ++   r+gk            v+r++k ++n+++ ++k          
   mKIAA0890   947 LIQV---RQGK------------VtRqGKfKpNSVTyRtK---------- 971  

                   dgnVsiHPsSvLfn...........................tkkkppkwv
                   +gn+++H s +++   ++ + +++++ ++   +++   ++++++ +++w+
   mKIAA0890   972 SGNILLHKSTINRWvatrvtyrgtqrmtrcvashsilfpreATRLRSRWL 1021 

                   vytelvetskkgdgskvYardvtaispewllllapgki<-*
                   +y   v++    +gs v++rd + + p ++lll +g++   
   mKIAA0890  1022 TYFMAVKS----NGS-VFVRDSSQVHPLAVLLLTDGDV    1054 

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