hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mpm/mpm03231/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0881  ( 1070 res)   mpm03231

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    300.0    1.7e-85   1
TyrKc    Tyrosine kinase, catalytic domain              103.9    1.9e-26   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
TyrKc      1/1      43   295 ..     1   280 []   103.9  1.9e-26
S_TKc      1/1      43   296 ..     1   231 []   300.0  1.7e-85

Alignments of top-scoring domains:
TyrKc: domain 1 of 1, from 43 to 295: score 103.9, E = 1.9e-26
                   *->ltlgkkLGeGaFGeVykGtlk...ieVAVKtLkeda.......keeF
                       + ++++G+G FG Vy ++  ++++ VA+K++  +++++++++ +++
   mKIAA0881    43    FSDLREIGHGSFGAVYFARDVrnsEVVAIKKMS-YSgkqsnekWQDI 88   

                   lrEakiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLl
                   ++E + + kl  +HpN ++  G+ + e       +  ++vmEy+ +G+  
   mKIAA0881    89 IKEVRFLQKL--RHPNTIQYRGCYLRE-------HTAWLVMEYC-LGSAS 128  

                   dyLrknrpklslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenk
                   d L  +++ l+  +     + + +G +YL+s+n +HRD  A N+L++e++
   mKIAA0881   129 DLLEVHKKPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPG 178  

                   vvKIsDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWmAPEsl..
                    vK +DFG +                +     g+       WmAPE++  
   mKIAA0881   179 LVKLGDFGSASIMAPA-------NSFV-----GTP-----YWMAPEVIla 211  

                   .kdgkFtskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevleylkkG
                    ++g +  k DVWS G+++ E+  + ++P  +     m++  +l ++ + 
   mKIAA0881   212 mDEGQYDGKVDVWSLGITCIELAER-KPPLFN-----MNAMSALYHIAQN 255  

                   yRlpkPendlpiSsvtCPdelYdlMlqCWaedPedRPtFsel.verl<-*
                   + +            + ++   +   +C +  P dRPt + l ++r+   
   mKIAA0881   256 ESPALQSG-------HWSEYFRNFVDSCLQKIPQDRPTSEVLlKHRF    295  

S_TKc: domain 1 of 1, from 43 to 296: score 300.0, E = 1.7e-85
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik..........eril
                      +  l+++G+G+FG Vy ard++  ++vAiK+++ ++++++++ ++i+
   mKIAA0881    43    FSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSysgkqsnekwQDII 89   

                   rEikiLkk.dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrgr
                   +E++ L+k +HPN +++ +++  ++  +lVmEyc G   +  dll+ +++
   mKIAA0881    90 KEVRFLQKlRHPNTIQYRGCYLReHTAWLVMEYCLG---SASDLLEVHKK 136  

                   rglrkvlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds..hvK
                   +     l E e++ +++  l++L+YLHs++ iHRD+K  NiLL++++ vK
   mKIAA0881   137 P-----LQEvEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEpgLVK 181  

                   laDFGlArql...ttfvGTpeYmAPEvl......gYgkpavDiWSlGcil
                   l+DFG+A ++ + ++fvGTp++mAPEv+   ++++Y++ +vD+WSlG++ 
   mKIAA0881   182 LGDFGSASIMapaNSFVGTPYWMAPEVIlamdegQYDG-KVDVWSLGITC 230  

                   yElltGkpPFp...qldlifkkig...........SpeakdLikklLvkd
                   +El+ +kpP  + + + +++++  ++++   ++++S+ ++++++ +L+k 
   mKIAA0881   231 IELAERKPPLFnmnAMSALYHIAQnespalqsghwSEYFRNFVDSCLQKI 280  

                   PekRlta.eaLedeldikaHPff<-*
                   P++R+t + +L+       H f+   
   mKIAA0881   281 PQDRPTSeVLLK-------HRFV    296  

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