hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg02428/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0858  ( 1625 res)   mbg02428

Scores for sequence family classification (score includes all domains):
Model     Description                                   Score    E-value  N 
--------  -----------                                   -----    ------- ---
PDZ       PDZ domain (Also known as DHR or GLGF)         21.3      0.012   1
E-MAP-115 E-MAP-115 family                              -79.5       0.34   1
TolA      TolA protein                                 -140.3       0.14   1

Parsed for domains:
Model     Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------  ------- ----- -----    ----- -----      -----  -------
PDZ         1/1     975  1055 ..     1    82 []    21.3    0.012
E-MAP-115   1/1    1217  1374 ..     1   193 []   -79.5     0.34
TolA        1/1    1111  1436 ..     1   448 []  -140.3     0.14

Alignments of top-scoring domains:
PDZ: domain 1 of 1, from 975 to 1055: score 21.3, E = 0.012
                   *->evtleke.vkrgglGfsikggsdkgivvsevlpGsgaAeagGrLkeG
                       v++   +     +Gf+ik   + gi+v++v +Gs+a   +  L+++
   mKIAA0858   975    RVSINQTpGNKPVFGFTIKWDIS-GIFVASVEQGSPAEFSQ--LQVD 1018 

                   DqIlsvNGqdvenlsheravlalkgsgg.sevtLtil<-*
                   D Il++N+++++     +  +++ ++ +++ + + ++   
   mKIAA0858  1019 DEILAINNTKFSYKDTKKWEEVMANAQEtGNLVMDVR    1055 

E-MAP-115: domain 1 of 1, from 1217 to 1374: score -79.5, E = 0.34
                   *->APgkaensaAlsKptAGTTDaeEAtrLLAEKRRqAReQrEkEEqERr
                      + +    s  ++  t   T  e    L  E  R   e r + E   +
   mKIAA0858  1217    SNSISLTSREPVAATWEATWSEGSKSLDSEGTRAGEEDRGQLEDDAV 1263 

                   eqeErdrrkREEl..krraaEeRtlrrEeEARrrEeeraRekeekKKqEG
                         +++  E+++kr++ E+     EeE R++ e +a  ++e+     
   mKIAA0858  1264 YEDQSQKLQELEQekKRKEQEAQ----EEERRKQREAQAWAEAEA----- 1304 

                   EEKRKAGEElkRkAEEeLLLKekrEqEeqErAmiqkQKEeAEaraREeAE
                       KA  E++ +AE e    +k   E q r        eAEa  R eA 
   mKIAA0858  1305 ----KAWAEAQARAEAE----AKARAEAQAR-------AEAEAQKRAEAQ 1339 

                   rvRlEREkhf.qqeEQERlERkKRLeEIMKRTRksevsekVKkeDskeG<
                   +   ERE+  + ++ Q R              R  +  +  K+eD   G 
   mKIAA0858  1340 KLQAERERETsVKIYQYR--------------RPIDSYDLPKREDDTSG  1374 

                   -*
                     
   mKIAA0858     -    -    

TolA: domain 1 of 1, from 1111 to 1436: score -140.3, E = 0.14
                   *->keqndklkrAiiISvvLHiiLialLilgSldetvepepgGeGggsvi
                      +   +k   +i+              l  l  ++     G  +++++
   mKIAA0858  1111    NPFDSKASESIS--------------LKNLKRRSQFFEQG--SSDSV 1141 

                   dAVm.VDpgaVaqQynrlqqQkedaarkekktEPvvEEkPvePdqeRkkk
                       +V +  +   +    +Q+e+ +r+e                     
   mKIAA0858  1142 APDLpVPTLSAPSRWAW--DQEEERRRQE-------------------RW 1170 

                   lqrqaeeleqkraaEqerlKeLekerlqaq...eaakkqaEearkqaeeq
                   +++q + l++k ++Eqe+l+e e +r+q++ ++e  k   Ee+       
   mKIAA0858  1171 QKEQDRLLQEKYQREQEKLRE-EWQRAQQEaerENSKYLDEELMVLNSNS 1219 

                   qKqaEEakakqakEaakaKaeAeaaKakeeaerkakeekaaAaAakkAEe
                     +     + +  Ea +  +    + +  e  r+ +e+        + E 
   mKIAA0858  1220 ISLTSREPVAATWEA-TWSEGS--KSLDSEGTRAGEED------RGQLED 1260 

                   eakakaAAeAkkkAeaeaAelkkkakarEaaaAeAkkkaeaEAkaKaaae
                   +a+ + +    ++ e+e+     k+k++Ea++ e +k+ ea A     ae
   mKIAA0858  1261 DAVYEDQSQKLQELEQEK-----KRKEQEAQEEERRKQREAQA----WAE 1301 

                   AeaKAkaEkAkAdaeAkaKAeaerkAdeeAAkeKAAAEAakKAaaekera
                   AeaKA aE A+A aeA aKA ae       A++ A AEA k+A+a k   
   mKIAA0858  1302 AEAKAWAE-AQARAEAEAKARAE-------AQARAEAEAQKRAEAQKL-- 1341 

                   aaaeakrKAAAEkaAaadqeaevdDifGsLssgkNapkqGggAkGagaas
                     ae++r       ++++             +     +            
   mKIAA0858  1342 -QAERERE------TSVK-----------IYQYR---RP----------- 1359 

                   adsGktkksGasGaevdqYagqiksaIqsrlldddsyaGKtCrvrikLap
                                  +d+Y    ++   s +l  d  + +  +     ++
   mKIAA0858  1360 ---------------IDSYDLPKREDDTSGMLPTDRSKSRSTTE----LN 1390 

                   DGtdallisvksegGDpalCqAAlaAvAktakiPkpPsddaVYeklKnin
                   D    l+    s   + ++ +   +   +  k   +Ps++     l   +
   mKIAA0858  1391 DP---LIEKNGSSKYSERIGATSFSH--RSSKKDQAPSEA----ELERQQ 1431 

                   ldfkl<-*
                   +  ++   
   mKIAA0858  1432 ILQEM    1436 

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