hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mia/mia12084/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0847  ( 1247 res)   mia12084

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic     74.6    1.2e-17   1
TyrKc    Tyrosine kinase, catalytic domain             -102.9      9e-05   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
TyrKc      1/1      67   311 ..     1   280 []  -102.9    9e-05
S_TKc      1/1      67   326 ..     1   231 []    74.6  1.2e-17

Alignments of top-scoring domains:
TyrKc: domain 1 of 1, from 67 to 311: score -102.9, E = 9e-05
                   *->ltlgkkLGeGaFGeVykG..tlk.ieVAVKtLkeda.keeFlrEaki
                       + ++k+G G FGe+y + ++l++++VA K+  +  +k+ +  E  +
   mKIAA0847    67    WKVLRKIGGGGFGEIYDAldMLTrENVALKVESAQQpKQVLKMEVAV 113  

                   MkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLldyLrkn
                   +kkl    +++ +++G+ + +          ++vm +  g +L d  r+ 
   mKIAA0847   114 LKKL-QGKDHVCRFIGCGRND-------RFNYVVMQL-QGRNLADLRRSQ 154  

                   rpk.lslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenk....v
                    + +++ s+ l    QI +  e ++s +f HRD+   N   g+  ++ + 
   mKIAA0847   155 SRGtFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPstcrK 204  

                   vKIsDFGLsRdlyddDkkG.eskdyYrkkggkggktllPirWmAPEslkd
                   +   DFGL+R  ++   +G+++    ++    g +    +r  ++ + + 
   mKIAA0847   205 CFMLDFGLARQFTNS--CGdVRPPRAVA----GFR--GTVRYASINAHRN 246  

                   gkFtskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevleylkkGyRl
                   ++     D WS       +f    +   g+    ++++ +  + + G   
   mKIAA0847   247 REMGRHDDLWS-------LFYMLVEFVVGQ----LPWRKIKDKEQVGSIK 285  

                   pkPendlpiSsvtCPdelYdlMlqCWaedPedRPtFselverl<-*
                   ++ ++              +lMl+    + +   tF + ++ l   
   mKIAA0847   286 ERYDH--------------RLMLKHLPPEFS---TFLDHISSL    311  

S_TKc: domain 1 of 1, from 67 to 326: score 74.6, E = 1.2e-17
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik.....erilrEiki
                      +++l+k+G G+FG+ y a d  t + vA+Kv + +++++ ++ E+++
   mKIAA0847    67    WKVLRKIGGGGFGEIYDALDMLTRENVALKVESaqqpkQVLKMEVAV 113  

                   Lkk..dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrgrrglr
                   Lkk ++ +++++++++ +++ + y+Vm + +    +L dl +++ r+   
   mKIAA0847   114 LKKlqGKDHVCRFIGCGRNdRFNYVVMQLQGR---NLADLRRSQSRGT-- 158  

                   kvlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds......hvK
                     ++ +++ ++ +Qil+ +e +Hs g++HRD+KP+N  + + +++ +   
   mKIAA0847   159 --FTIsTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRfpstcrKCF 206  

                   laDFGlArql.............ttfvGTpeYmAPEvl...gYgkpavDi
                     DFGlArq++++ ++ ++++    f GT  Y +    +++  g+   D 
   mKIAA0847   207 MLDFGLARQFtnscgdvrppravAGFRGTVRYASINAHrnrEMGR-HDDL 255  

                   WSlGcilyElltGkpPFp..qldlifkkig............SpeakdLi
                   WSl  +l E+++G+ P+++  +++    i+++++++   ++ +pe+  ++
   mKIAA0847   256 WSLFYMLVEFVVGQLPWRkiKDKEQVGSIKerydhrlmlkhlPPEFSTFL 305  

                   kklLvkdPekRlta.eaLedeldikaHPff<-*
                   +++   d       +  L           f   
   mKIAA0847   306 DHISSLDYF--TKPdYQLL-------TSVF    326  

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