hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mpg/mpg00938/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0834  ( 453 res)   mpg00938

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    297.5    9.4e-85   1
TyrKc    Tyrosine kinase, catalytic domain              -27.0    1.8e-09   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
S_TKc      1/1     119   403 ..     1   231 []   297.5  9.4e-85
TyrKc      1/1     119   403 ..     1   280 []   -27.0  1.8e-09

Alignments of top-scoring domains:
S_TKc: domain 1 of 1, from 119 to 403: score 297.5, E = 9.4e-85
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik........erilrE
                      Ye+l+klG+G++++Vy+++ k  g+lvA+Kvi+ +++++++ +++rE
   mKIAA0834   119    YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRlqeeegtpFTAIRE 165  

                   ikiLkk.dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrgrrg
                    ++Lk  +H NIV L+d++++++ l lV+Ey+ +   dL ++++k++++ 
   mKIAA0834   166 ASLLKGlKHANIVLLHDIIHTkETLTLVFEYVHT---DLCQYMDKHPGG- 211  

                   lrkvlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds..hvKla
                       l+++ ++ ++ Q+l++L Y+H++ I+HRDLKP+N+L+++++++Kla
   mKIAA0834   212 ----LHPdNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDtgELKLA 257  

                   DFGlArql.......ttfvGTpeYmAPEvl....gYgkpavDiWSlGcil
                   DFGlAr  + ++++ +  v+T++Y++P vl +++ Y++   D+W +Gci+
   mKIAA0834   258 DFGLARAKsvpshtySNEVVTLWYRPPDVLlgstEYST-CLDMWGVGCIF 306  

                   yElltGkpPFp.......qldlifkkig......................
                    E++ G   Fp+ ++ ++ql++if ++g+++++++++ ++ ++ ++++ +
   mKIAA0834   307 VEMIQGVAAFPgmkdiqdQLERIFLVLGtpnedtwpgvhslphfkperft 356  

                   ................SpeakdLikklLvkdPekRlta.eaLedeldika
                    +++++ +  +++ ++   a dL +klL+  P++Rl+a+ aL        
   mKIAA0834   357 vysskslrqawnklsyVNHAEDLASKLLQCSPKNRLSAqAALS------- 399  

                   HPff<-*
                   H++f   
   mKIAA0834   400 HEYF    403  

TyrKc: domain 1 of 1, from 119 to 403: score -27.0, E = 1.8e-09
                   *->ltlgkkLGeGaFGeVykGtlk...ieVAVKtLkeda....keeFlrE
                       ++++kLGeG + +VykG+ k ++  VA K+++   ++++    +rE
   mKIAA0834   119    YEKLEKLGEGSYATVYKGKSKvngKLVALKVIRLQEeegtPFTAIRE 165  

                   akiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLldyL
                   a+++k l  kH NiV L+ ++ ++       e l +v+Ey+ + dL +y 
   mKIAA0834   166 ASLLKGL--KHANIVLLHDIIHTK-------ETLTLVFEYV-HTDLCQYM 205  

                   rknrpklslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenkvvK
                    k+ + l ++    f +Q  +G +Y++++ + HRDL   N L+++ +  K
   mKIAA0834   206 DKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELK 255  

                   IsDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWmAPEsl.kdgk
                    +DFGL+R+          + +Y+     ++   + +   +P +l    +
   mKIAA0834   256 LADFGLARAKSVP------SHTYS-----NEV--VTLWYRPPDVLlGSTE 292  

                   FtskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevleylkkGyRlpk
                   +++  D W  G    E+   G    pg+    ++ ++ le++     l  
   mKIAA0834   293 YSTCLDMWGVGCIFVEMI-QGVAAFPGM----KDIQDQLERI--FLVLGT 335  

                   Pendl.p.iS.........................s.vtCPdelYdlMlq
                   P +d  p++ + ++ ++++ +  ++++ ++  ++ s v   ++l +  lq
   mKIAA0834   336 PNEDTwPgVHslphfkperftvysskslrqawnklSyVNHAEDLASKLLQ 385  

                   CWaedPedRPtFsel..verl<-*
                   C    P++R + ++  ++e++   
   mKIAA0834   386 C---SPKNRLSAQAAlsHEYF    403  

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