hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpg/mpg00938/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0834  ( 453 res)   mpg00938

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       279.5    4.4e-80   1
Pkinase_Tyr Protein tyrosine kinase                       2.8    4.7e-12   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Pkinase_Tyr   1/1     119   355 ..     1   272 []     2.8  4.7e-12
Pkinase       1/1     119   403 ..     1   287 []   279.5  4.4e-80

Alignments of top-scoring domains:
Pkinase_Tyr: domain 1 of 1, from 119 to 355: score 2.8, E = 4.7e-12
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtLk....eigass
                       ++++kLGeG++ +VykG+ k     ++  VA K+++ +++e g+  
   mKIAA0834   119    YEKLEKLGEGSYATVYKGKSK----VNGKLVALKVIRlqeeE-GTPF 160  

                   eeieredFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEyme
                    +      +rEAs++k l +H NiV L+ ++   +e     l +V+Ey++
   mKIAA0834   161 TA------IREASLLKGL-KHANIVLLHDIIHT-KET----LTLVFEYVH 198  

                   gGdLldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARN
                     dL  ++ kh  ++ L       f +Q  +G++Y +++ + HRDL   N
   mKIAA0834   199 T-DLCQYMDKH--PGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQN 245  

                   cLVsenlvVKIsDFGLaRdi......ynddyYvrkkgggklPvkWm.APE
                    L+s+++  K +DFGLaR+ + ++++y+ +   +++        W+++P 
   mKIAA0834   246 LLISDTGELKLADFGLARAKsvpshtYSNE---VVTL-------WYrPPD 285  

                   slkygk.FtskSDVWSFGVlLWEiftlGeqPFYpgm.sneevlellyedG
                   +l  + ++++  D W  G+   E++  G    +pgm++ ++ le++    
   mKIAA0834   286 VLLGSTeYSTCLDMWGVGCIFVEMIQ-GVAA-FPGMkDIQDQLERIF--- 330  

                   yRLpr.PenCPdelYdlMlqCWaedPedRPtFselverL<-*
                     L  + e++++ +++l            P F+   er+   
   mKIAA0834   331 LVLGTpNEDTWPGVHSL------------PHFKP--ERF    355  

Pkinase: domain 1 of 1, from 119 to 403: score 279.5, E = 4.4e-80
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      ye+leklG+Gs++tVyk+k k +gk+VA+K+i++++e+   + ta+r
   mKIAA0834   119    YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEG-TPFTAIR 164  

                   rsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGL.rlldLfdyls
                     E+++lk L+H NIv l+d+ ++k  l lV+Ey+  +L + +d +    
   mKIAA0834   165 --EASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLcQYMDKH---- 208  

                   etrrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldeng
                        g+l   +d +k ++ Q+lrgl Y+H++ i+HRDLKP+N+L++++g
   mKIAA0834   209 ----PGGL--HPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTG 252  

                   vvdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggngygtkv
                   ++    K+aDFGlA+ +   +s++++  v+T+wY++P vllg+++y+t  
   mKIAA0834   253 EL----KLADFGLARAK-SvPSHtYSNEVVTLWYRPPDVLLGSTEYSTCL 297  

                   DvWSlGvilyelltGkpPFsgevqds.ldqlqlirkilgpplefdspewd
                   D+W++G+i+ e++ G   F+g   ++  dql++i+++lg+p+e  +p ++
   mKIAA0834   298 DMWGVGCIFVEMIQGVAAFPGM--KDiQDQLERIFLVLGTPNEDTWPGVH 345  

                   sisrse.fr...........r.l.pnlseeakdLikkcLnkDPskRltae
                   s + +++ r +  ++++ ++  ++      a dL +k+L+  P+ Rl+a+
   mKIAA0834   346 SLPHFKpERftvysskslrqAwNkLSYVNHAEDLASKLLQCSPKNRLSAQ 395  

                   eilqHPwf<-*
                    +l H++f   
   mKIAA0834   396 AALSHEYF    403  

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