hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg15128/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0812  ( 1147 res)   mbg15128

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
7tm_2    7 transmembrane receptor (Secretin family)     323.6    2.3e-93   1
GPS      Latrophilin/CL-1-like GPS domain                81.1    2.3e-20   1
Frizzled Frizzled/Smoothened family membrane region    -207.7       0.56   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
GPS        1/1     312   365 ..     1    55 []    81.1  2.3e-20
7tm_2      1/1     372   615 ..     1   296 []   323.6  2.3e-93
Frizzled   1/1     358   629 ..     1   343 []  -207.7     0.56

Alignments of top-scoring domains:
GPS: domain 1 of 1, from 312 to 365: score 81.1, E = 2.3e-20
                   *->tnpiCvfWdessl.estgvWstdrGCevveenkpshttCsCnHLTtF
                      +++iCv+Wd    ++++g W++ r+Ce+v++n+ sh++C+C++ +tF
   mKIAA0812   312    SKAICVQWDPPGPtDQHGMWTA-RDCELVHRNG-SHARCRCSRTGTF 356  

                   Avlmdvppn<-*
                   +vlmd++p+   
   mKIAA0812   357 GVLMDASPR    365  

7tm_2: domain 1 of 1, from 372 to 615: score 323.6, E = 2.3e-93
                   *->lllLkviytVGyslSSLvaLllAiaifllfRkLhCtRnyIHlNLfas
                      l+lL v ++V++++S  +aL+l+ a++l +R+L+++   IH N  a+
   mKIAA0812   372    LELLAVFTHVVVAVS-VTALVLTAAVLLSLRSLKSNVRGIHANVAAA 417  

                   fiLralsfLikdavlfnsvglseadqlsweeslhcsasagkitmivvVgC
                   + +++l+fL+++++++n+                               C
   mKIAA0812   418 LGVAELLFLLGIHRTHNQLL-----------------------------C 438  

                   kvvavflhYfflaNFfWmLVEGlYLhtllvvtvevffserkrfwwYlliG
                   ++va++lhYffl++F+W+LV Gl+L+++    ve+++ +r+ +++Y+ +G
   mKIAA0812   439 TAVAILLHYFFLSTFAWLLVQGLHLYRMQ---VEPRNVDRGAMRFYHALG 485  

                   WGvPavfvgiwaivrpdkwagygnegCCWlsnedngyfwWiikGPvllvI
                   WGvPav+ g++++++p+   gygn+++CW+s+  + +++W+++GP++lvI
   mKIAA0812   486 WGVPAVLLGLAVGLDPE---GYGNPDFCWISI--HEPLIWSFAGPIVLVI 530  

                   lvNfilFinilriLvqKlridkslspqmgetdqyrkkrlakstLlLlPLL
                   ++N  +F++ +r+ ++  +      +++++t + r   +++s++lLl+L+
   mKIAA0812   531 VMNGTMFLLAARTSCSTGQ------REAKKTSVLR---TLRSSFLLLLLV 571  

                   GitwvlflfapeddsqGvssivflylfliLnSfQGffVavlYCFlNgEV<
                     +w+++l+a+++     s  +f+yl+++L+ +QG+ V +l+C+lN +  
   mKIAA0812   572 SASWLFGLLAVNH-----SILAFHYLHAGLCGLQGLAVLLLFCVLNADA  615  

                   -*
                     
   mKIAA0812     -    -    

Frizzled: domain 1 of 1, from 358 to 629: score -207.7, E = 0.56
                   *->mlFsedEkrfarsWigvwSalCflSTLFTvlTFLIDmkNRFrYPERP
                      +l + + ++ +     + ++++ ++ + +v+  +             
   mKIAA0812   358    VLMDASPRERLEGDLELLAVFTHVVVAVSVTALVLTAA--------- 395  

                   IiFLSaCYlivSlgYLiglvlGaresvaCrkaeeaeagertvtqgstent
                              Sl  L  +v G +  va      ae    +++  +   +
   mKIAA0812   396 --------VLLSLRSLKSNVRGIHANVAAA-LGVAELLFLLGIHRTHNQL 436  

                   sCtvlFlllYFFgMAssvWWViLtlTWFLAAglKWGthEAIeakss.YFH
                   +Ct+++ ll +F+ + ++W ++  l ++    + +  +   +  + +  H
   mKIAA0812   437 LCTAVAILLHYFFLSTFAWLLVQGLHLY---RMQVE-PRNVDRGAMrFYH 482  

                   laAWglPavlTItvLalnkVDGDelsGiCfVGnlNlda........LrgF
                   ++ Wg+Pavl    L l+       +G+   G+ N+d    + +++L + 
   mKIAA0812   483 ALGWGVPAVL----LGLA-------VGLDPEGYGNPDFcwisihepLIWS 521  

                   VLaPLclyLvi.GtsFLlaGfvSLFrIRsviktdgsetktdKLeKLMvRI
                   + +P++l++v +Gt+FLla        R++  t+   + + K   L    
   mKIAA0812   522 FAGPIVLVIVMnGTMFLLA-------ARTSCSTGQ--REAKKTSVLRTLR 562  

                   GvFsvLYtVPaliviaCyfYEqanrdeWerswldcickqysDReLvtiPc
                     F +L +V a  +++ +     ++++     l+  ++ ++         
   mKIAA0812   563 SSFLLLLLVSASWLFGLLAVNHSILAFH---YLHAGLCGLQ--------- 600  

                   PvkdksgdpearPeslaVfmlKylmsLvVGItsgvWVwSsKTlesWrrfi
                                  laV++l  ++           V+ +    +W  ++
   mKIAA0812   601 -------G-------LAVLLL--FC-----------VLNADARAAWTPAC 623  

                   rrlcgr<-*
                     ++++   
   mKIAA0812   624 LGKKAA    629  

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