hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg06488/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0787  ( 419 res)   mbg06488

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    221.2    9.2e-62   1
TyrKc    Tyrosine kinase, catalytic domain              -28.6    2.3e-09   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
TyrKc      1/1      17   234 ..     1   280 []   -28.6  2.3e-09
S_TKc      1/1      18   240 ..     1   231 []   221.2  9.2e-62

Alignments of top-scoring domains:
TyrKc: domain 1 of 1, from 17 to 234: score -28.6, E = 2.3e-09
                   *->ltlgkkLGeGaFGeVykGtlkieVAVKtLkeda.keeFlrEakiMkk
                                                 ++++  ++e  ++E+ i+kk
   mKIAA0787    17    ---------------------------CIQPRGpIEQVYQEIAILKK 36   

                   lGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLldyLrknrpk
                   l  +HpN+VkL+ v  ++ +     + l++v+E++  G   +     +p 
   mKIAA0787    37 L--DHPNVVKLVEVLDDPNE-----DHLYMVFELVNQGPVME-VPTLKP- 77   

                   lslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenkvvKIsDFGL
                   ls ++   +  +  kG eYL+ ++++HRD+   N Lvge++++KI+DFG 
   mKIAA0787    78 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGV 127  

                   sRdlyddDkkGeskdyYrkkggkggktllPirWmAPEsl..kdgkFtskS
                   s + +         d         ++t+     mAPEsl++  ++F+ k 
   mKIAA0787   128 SNEFKGS-------DAL------LSNTVGTPAFMAPESLseTRKIFSGKA 164  

                   .DVWSFGVlLWEiftlGeqPYpgeiqq.fmsneevleylkkGyRlpkPen
                    DVW+ GV+L+  f +G+ P  +e  + ++  + +  +  +   +++P+ 
   mKIAA0787   165 lDVWAMGVTLY-CFVFGQCPFMDE--RiMCLHSKIKSQALEF--PDQPDI 209  

                   dlpiSsvtCPdelYdlMlqCWaedPedRPtFselverl<-*
                             ++l dl+++  + +Pe+R     +v ++   
   mKIAA0787   210 ---------AEDLKDLITRMLDKNPESR----IVVPEI    234  

S_TKc: domain 1 of 1, from 18 to 240: score 221.2, E = 9.2e-62
                   *->YellkklGkGaFGkVylardkktgrlvAiKvikerilrEikiLkk.d
                       +   ++                          e++++Ei+iLkk d
   mKIAA0787    18    IQPRGPI--------------------------EQVYQEIAILKKlD 38   

                   HPNIVkLydvfed...dklylVmEyceGdlGdLfdllkkrgrrglrkvls
                   HPN+VkL +v +d+++d+ly+V+E++++  G ++++   ++       ls
   mKIAA0787    39 HPNVVKLVEVLDDpneDHLYMVFELVNQ--GPVMEVPTLKP-------LS 79   

                   E.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds..hvKlaDFGlAr
                   E++arfyf+ +++++eYLH q+IiHRD+KP+N+L+ +++h+K+aDFG++ 
   mKIAA0787    80 EdQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEdgHIKIADFGVSN 129  

                   ql.......ttfvGTpeYmAPEvl.....gYgkpavDiWSlGcilyEllt
                   ++++++   +  vGTp +mAPE l+++++ ++++a D+W+ G++ly ++ 
   mKIAA0787   130 EFkgsdallSNTVGTPAFMAPESLsetrkIFSGKALDVWAMGVTLYCFVF 179  

                   GkpPFp..qldlifkkig............SpeakdLikklLvkdPekRl
                   G+ PF ++ ++ +  ki++   + ++ ++  +++kdLi ++L+k+Pe R+
   mKIAA0787   180 GQCPFMdeRIMCLHSKIKsqalefpdqpdiAEDLKDLITRMLDKNPESRI 229  

                   ta.eaLedeldikaHPff<-*
                    ++e+         HP++   
   mKIAA0787   230 VVpEIKL-------HPWV    240  

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