hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj22320/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0771  ( 1105 res)   mfj22320

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N 
--------   -----------                                  -----    ------- ---
Ank        Ankyrin repeat                                77.8    2.2e-19   2
SH3_1      SH3 domain                                    65.5    1.2e-15   1
SH3_2      Variant SH3 domain                            36.5      6e-07   1
Vicilin_N  Vicilin N terminal region                    -72.5       0.48   1
Extensin_2 Extensin-like region                        -118.8      0.073   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
Vicilin_N    1/1      99   216 ..     1   183 []   -72.5     0.48
Extensin_2   1/1     439   768 ..     1   385 []  -118.8    0.073
Ank          1/2     935   967 ..     1    33 []    43.4  5.2e-09
Ank          2/2     968  1000 ..     1    33 []    34.8  1.9e-06
SH3_1        1/1    1037  1094 ..     1    58 []    65.5  1.2e-15
SH3_2        1/1    1038  1094 ..     1    69 []    36.5    6e-07

Alignments of top-scoring domains:
Vicilin_N: domain 1 of 1, from 99 to 216: score -72.5, E = 0.48
                   *->pGRrnYeDDPqqrYEqCqRRCesetrGqrEQqqCEeRCkeqykEeqq
                         r  eD P    Eq  R    +t +qr Q        e   E   
   mKIAA0771    99    ---RH-EDSPTESSEQGAR----QTQEQRTQRSVVNVPGEKRTENGV 137  

                   qqRqReE....DPQrrYeeCqqrCqqeETEeRhrptCqQrCerrYEkeqq
                    +  R E + +++Q          +q+                + E +qq
   mKIAA0771   138 GN-PRVEltlsELQ------DMAARQQQ---------------QIENQQQ 165  

                   qQQKRYEEQQREDEEKYEERmKEEDNKRDPqqRqyqeCQqRCqqQEQrPr
                                                      +e + +   Q+   r
   mKIAA0771   166 M-------------------------------LVAKEQRLHFLKQQ--ER 182  

                   rqQQCqReCREQYqEqqerGeeenknPQWReeeeersEEG<-*
                   rqQQ + e  E+ q   er e  +        ++ r   G   
   mKIAA0771   183 RQQQSVSE-NEKLQKLKERVEAQEN-----KLKKIRAMRG    216  

Extensin_2: domain 1 of 1, from 439 to 768: score -118.8, E = 0.073
                   *->lltlvvalvslslpseasakYsYsSPPPpekpYvYkSPPpPspkyvy
                       ++  + ++s   ++e       + PPP            P    v 
   mKIAA0771   439    AISSQPLPLSALGATEKLGIEIGKGPPPI-----------PG---VG 471  

                   kSPPPpkkpYvYsSPPPPsyvykSPPPPkpyvYkSPPpPkyvYkSPPpPv
                   k  PP+   Y  s P  P     S    ++    S P+P        pP+
   mKIAA0771   472 KPLPPSYGTYPSSGPLGP----GSTSSLERRKEGSLPRPGAG-----PPS 512  

                   ykYkSPPPPthsppPpyvykSPPPPpk..kyvykSpPpptPvYkYkSPPP
                        P PP          + P P + ++     S+Pp +P Y    PP 
   mKIAA0771   513 RQKPAPLPPA--------SNAPQPGSSqqIQQRISVPP-SPTYPPAGPPA 553  

                   PpyvYkspPpPvkkripyvY..kSPPPPpPYvYkSpPppvkkyiyksppp
                    p     p  P    i++   +k   P +P   +  P  v     +s+  
   mKIAA0771   554 FPTGDGKPELPLTVAIRPFLadKGSRPQSP---RKGPQTV-----NSSSI 595  

                   pephkYvYkSPPPPpPYv..yesvpeqkikYvYkSPPPPkksYkspsppk
                   ++   Y  +  PP   Y ++ +  +++++k vY  P  P+    spsp +
   mKIAA0771   596 YSM--YLQQATPPKN-YQppAHGTLNKSVKAVYGKPVLPS-GSASPSPLP 641  

                   yVYkSpPpPvipykYkSPPPPkkkyspaPrkpyvYkSPPPPt..yvYkSp
                   + + S    +       P PP+ + +    k +    P  P ++    S 
   mKIAA0771   642 FLHGSLGTGT-----AQPQPPSDSAE----KEPEQEGPSVPGegSTVESL 682  

                   PpPykpptppkiyksPPPPtPvyvYkspPpippik...sssppPvyvYkS
                   P+P  p +  +i  sP        Y+s   +  ++++ +  p P  +  S
   mKIAA0771   683 PRPLSPTKLTPIVHSP------LRYQSDADLEALRrklANAPRPLKKRSS 726  

                   pPppvysPPPPyvYssPPPPvy...vynsaPvykksPPkhhYiYsSPPPp
                      p            P  P  ++ +y+            +++  SP   
   mKIAA0771   727 ITEPE----------GPGGPNIqklLYQRFNTLAGGMEGTPFYQPSPSQD 766  

                   hh<-*
                   +    
   mKIAA0771   767 FV    768  

Ank: domain 1 of 2, from 935 to 967: score 43.4, E = 5.2e-09
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                      +G TPLH A++ g++ +vk+Ll+ G ++na d    
   mKIAA0771   935    EGITPLHNAVCAGHHHIVKFLLDFGVNVNAADS    967  

Ank: domain 2 of 2, from 968 to 1000: score 34.8, E = 1.9e-06
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                      dG+TPLH+Aa+++++ ++k L++ GA + a +    
   mKIAA0771   968    DGWTPLHCAASCNSVHLCKQLVESGAAIFASTI    1000 

SH3_1: domain 1 of 1, from 1037 to 1094: score 65.5, E = 1.2e-15
                   *->kkvvALYDYearesdELsFkkGDvitvleksdd...gWWkgrlkgtg
                       +v AL DYea++sdELsF +GD it+l ++d+++++WW +rl    
   mKIAA0771  1037    GTVYALWDYEAQNSDELSFHEGDAITILRRKDEnetEWWWARLG--- 1080 

                   GkeGliPsNYVepv<-*
                   ++eG++P N + ++   
   mKIAA0771  1081 DREGYVPKNLLGLY    1094 

SH3_2: domain 1 of 1, from 1038 to 1094: score 36.5, E = 6e-07
                   *->ygraiedyvaAtdknenleeeeLslkkGdvvkvidvggskddd..gw
                       + a+ dy+a ++ +e      Ls+++Gd + ++   + kd ++++w
   mKIAA0771  1038    TVYALWDYEA-QNSDE------LSFHEGDAITIL---RRKDENetEW 1074 

                   wlgeslggGrrrRGlvPssaveel<-*
                   w++++  g r+  G+vP +++  +   
   mKIAA0771  1075 WWARL--GDRE--GYVPKNLLGLY    1094 

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