hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg11441/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0762  ( 729 res)   mbg11441

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
Spond_N  Spondin_N                                      548.5   4.5e-161   1
Reeler   Reeler domain                                  272.2    6.6e-78   1
TSP_1    Thrombospondin type 1 domain                   265.7    6.3e-76   4

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Reeler     1/1      42   172 ..     1   150 []   272.2  6.6e-78
Spond_N    1/1     173   414 ..     1   253 []   548.5 4.5e-161
TSP_1      1/4     445   493 ..     1    55 []    63.9  3.4e-15
TSP_1      2/4     540   587 ..     1    55 []    90.8  2.7e-23
TSP_1      3/4     594   642 ..     1    55 []    69.9  5.5e-17
TSP_1      4/4     680   729 .]     1    55 []    63.8  3.6e-15

Alignments of top-scoring domains:
Reeler: domain 1 of 1, from 42 to 172: score 272.2, E = 6.6e-78
                   *->fCsrilpahgkgdksegsnefslkiegsptksmDisksyvPGetYrV
                      +Csril+a+g  +++eg++efsl++eg+p+       +y+PG+ YrV
   mKIAA0762    42    YCSRILRAQG--TRREGYTEFSLRVEGDPD-------FYKPGSSYRV 79   

                   tiRGWRtqsgtSPeyFRGFlLtalkegregeseedpaGsssFqlideedt
                   t+      s+ +P+yFRGF+L+alke++eg++eed+aG  +Fq+idee+t
   mKIAA0762    80 TL------SAAPPSYFRGFTLIALKENQEGDKEEDHAG--TFQIIDEEET 121  

                   qfptedgCpvAVshasssrktrisvfWkAPpagsGCVvFrATvvqrkiIy
                   qf++  +CpvAV++++++r+tri+vfW+APp+g+GCV+++A++vq++iIy
   mKIAA0762   122 QFMS--NCPVAVTESTPRRRTRIQVFWIAPPTGTGCVILKASIVQKRIIY 169  

                   Fqd<-*
                   Fqd   
   mKIAA0762   170 FQD    172  

Spond_N: domain 1 of 1, from 173 to 414: score 548.5, E = 4.5e-161
                   *->dgsLTkrrlCeekpd..alasppatptaplttCcAcdeAkYrlvFeG
                      +gsLTk+ lCe++p+ + ++++p        +CcAc++AkYrl+F+G
   mKIAA0762   173    EGSLTKK-LCEQDPTldGVTDKPI------LDCCACGTAKYRLTFYG 212  

                   kWSrnThPKDYPlfrpptqWskliGasHSsnYrLWeyGgyASeGmKefAE
                   +WS++ThPKDYP  r++++Ws++iG sHS+nY+LWeyGgyASeG+K++AE
   mKIAA0762   213 NWSEKTHPKDYP--RRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAE 260  

                   wGstvkLekEirEkaqgqevRsVikafglpaiwqPPngtGttsaefrVdp
                    Gs+vk+e+Ei  ++q++ev +Vika++++++wqP+n+++++saef+Vd+
   mKIAA0762   261 LGSPVKMEEEI--RQQSDEVLTVIKAKAQWPAWQPVNVRAAPSAEFSVDR 308  

                   rHhlvSLatkigPSPDWfVGVdgLeLClgdCtWkEevtfdLyPwDAGTDS
                   ++hl+S++t++gPSPDW+VG+++++LC+++C+W+++v++dL+PwDAGTDS
   mKIAA0762   309 TRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDS 358  

                   GfTysSPNePTiPqevIrrITSsyPshPasPFYyprgkplpPlAtvyltR
                   G+Ty+SPN+PTiPqe+Ir++TS +  hP+sPFY+p+g++++++A+v+++R
   mKIAA0762   359 GVTYESPNKPTIPQEKIRPLTSLD--HPQSPFYDPEGGSITQVARVVIER 406  

                   kkryerec<-*
                   ++r++++c   
   mKIAA0762   407 IARKGEQC    414  

TSP_1: domain 1 of 4, from 445 to 493: score 63.9, E = 3.4e-15
                   *->spWseWSpCSV.TCGkGirtRqRvcnspaPqkkggepCtgdvqelet
                      s+Ws+WS+CS +TC kG r+RqR+ +++    + + pC++++    +
   mKIAA0762   445    SNWSPWSACSSsTCEKGKRMRQRMLKAQL---DLSVPCPDTQD---F 485  

                   eaCdmmdkC<-*
                   ++C m + C   
   mKIAA0762   486 QPC-MGPGC    493  

TSP_1: domain 2 of 4, from 540 to 587: score 90.8, E = 2.7e-23
                   *->spWseWSpCSVTCGkGirtRqRvcnspaPqkkggepCtgdvqelete
                      spWseWS+CSVTCGkG+rtRqR+ +s     ++ ++C +d ++   e
   mKIAA0762   540    SPWSEWSDCSVTCGKGMRTRQRMLKSL----AELGDCNEDLEQ--AE 580  

                   aCdmmdkC<-*
                   +C m ++C   
   mKIAA0762   581 KC-MLPEC    587  

TSP_1: domain 3 of 4, from 594 to 642: score 69.9, E = 5.5e-17
                   *->spWseWSpCSVTCGkGirtRqRvcnspaPqkkggepCtgdvqelete
                      s+Ws+WS+C+++CGkG+++R+R+++++ Pq +gg pC+++vq+   +
   mKIAA0762   594    SEWSQWSECNKSCGKGHMIRTRTIQME-PQ-FGGVPCPETVQR---K 635  

                   aCdmmdkC<-*
                   +C + +kC   
   mKIAA0762   636 KC-RTRKC    642  

TSP_1: domain 4 of 4, from 680 to 729: score 63.8, E = 3.6e-15
                   *->spWseWSpCSVTCGkGirtRqRvcnspaPqk.kggepCtgdvqelet
                       pW+ WS+C++ CG+Gi++R++++++++  k+++  +C+++++   +
   mKIAA0762   680    RPWTAWSECTKLCGGGIQERYMTVKKRF--KsSQFTSCKDKKE---I 721  

                   eaCdmmdkC<-*
                   +aC ++++C   
   mKIAA0762   722 RAC-NVHPC    729  

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