hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg07395/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0718  ( 769 res)   mbg07395

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
DAGKa    Diacylglycerol kinase accessory domain (pres   366.1   2.1e-105   1
DAGKc    Diacylglycerol kinase catalytic domain (pres   241.8    5.8e-68   1
C1       Protein kinase C conserved region 1 (C1) dom    93.6    2.3e-23   2
EFh      EF-hand, calcium binding motif                  54.2    1.7e-11   2

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
EFh        1/2     119   147 ..     1    29 []    29.4  0.00051
EFh        2/2     164   192 ..     1    29 []    26.8   0.0031
C1         1/2     209   260 ..     1    61 []    67.5  1.6e-15
C1         2/2     276   324 ..     1    61 []    34.0  2.1e-05
DAGKc      1/1     403   527 ..     1   157 []   241.8  5.8e-68
DAGKa      1/1     547   727 ..     1   195 []   366.1 2.1e-105

Alignments of top-scoring domains:
EFh: domain 1 of 2, from 119 to 147: score 29.4, E = 0.00051
                   *->elkeaFrefDkDgdGkIdfeEfkallksl<-*
                      +l+ +Fr++D+Dg+G++d  E+  ++  +   
   mKIAA0718   119    KLEFMFRLYDTDGNGFLDSSELENIIGQM    147  

EFh: domain 2 of 2, from 164 to 192: score 26.8, E = 0.0031
                   *->elkeaFrefDkDgdGkIdfeEfkallksl<-*
                       l e+++e+D D+dG++++eE++++ ++    
   mKIAA0718   164    ILHEMMEEIDYDRDGTVSLEEWIQGGMTT    192  

C1: domain 1 of 2, from 209 to 260: score 67.5, E = 1.6e-15
                   *->Hkfvfrtf...kptfCdvCrksiwgsfkqaaksqglrCseCkvkcHk
                       ++v+r ++ +kp++C++C  +++g+ kq     gl+Cs Ck+++H+
   mKIAA0718   209    GQHVWRLKhfnKPAYCNLCLNMLIGVGKQ-----GLCCSFCKYTVHE 250  

                   kCaekvpaqshksglsC<-*
                   +C++++p+       sC   
   mKIAA0718   251 RCVARAPP-------SC    260  

C1: domain 2 of 2, from 276 to 324: score 34.0, E = 2.1e-05
                   *->HkfvfrtfkptfCdvCrksiwgsfkqaaksqglrCseCkvkcHkkCa
                      H +v++++ pt+Cd C+k++++++  +    gl C +C+ + H+kCa
   mKIAA0718   276    HYWVEGNC-PTKCDKCHKTVKCYQGLT----GLHCVWCQTTLHNKCA 317  

                   ekvpaqshksglsC<-*
                   +++ +        C   
   mKIAA0718   318 SHLKP-------EC    324  

DAGKc: domain 1 of 1, from 403 to 527: score 241.8, E = 5.8e-68
                   *->plLVfvNPkSGggqgeellkseskllrkfrelLnprqVfdltktggp
                      plLVfvNPkSGg+qge       ++ rkf++lLnprqV+ l++ +gp
   mKIAA0718   403    PLLVFVNPKSGGKQGE-------RIYRKFQYLLNPRQVYSLSG-NGP 441  

                   dvglelefrdvpkfkeqsdqkgddrvlvcGGDGTvgwVlnaldkrelplq
                    +gl++ frdvp+f          rvl+cGGDGTvgw+l++++k++  ++
   mKIAA0718   442 MPGLHF-FRDVPDF----------RVLACGGDGTVGWILDCIEKANVVKH 480  

                   cqvedrefpePPvailPlGTGNdLarvLgwgggydginekllkilkeale
                             PPvailPlGTGNdLar+L+wgggy+g  e+l+kilk+++ 
   mKIAA0718   481 ----------PPVAILPLGTGNDLARCLRWGGGYEG--ENLMKILKDIE- 517  

                   eadtvkldrW<-*
                    +  ++ldrW   
   mKIAA0718   518 SSTEIMLDRW    527  

DAGKa: domain 1 of 1, from 547 to 727: score 366.1, E = 2.1e-105
                   *->iMNNYFSiGvDAkiaLeFHnsREanPekFnSRlkNKlwYfelGtkel
                      i+NNYFSiGvDA+ia++FH++RE++PekFnSR+kNK+wYfe+Gt+e+
   mKIAA0718   547    IINNYFSIGVDASIAHRFHIMREKHPEKFNSRMKNKFWYFEFGTSET 593  

                   fartcKdLheqIeLecDGvdidlpnkdlslEGIivLNIPSygGGtnLWGe
                   f +tcK+Lhe++e+ecDGv idl n  +slEGI++LNIPS++GG+nLWGe
   mKIAA0718   594 FSATCKKLHESVEIECDGVQIDLIN--ISLEGIAILNIPSMHGGSNLWGE 641  

                   Pfgskkkravcgifkk......sftdkedlnfekqsidDgllEVVGvtga
                      skkkr   +i kk+++++++ td ++l+f+ q+++D+llEVVG++ga
   mKIAA0718   642 ---SKKKRSHRRIEKKgsdkrpTLTDAKELKFASQDLSDQLLEVVGLEGA 688  

                   mhmaqvrtsiqvglasiilvkllKgrRiaQCsevrlkdtiltkktiPmQV
                   m+m+q++t  +++ a         grR+aQCs v    +i+t+k++PmQ+
   mKIAA0718   689 MEMGQIYT--GLKSA---------GRRLAQCSSV----VIRTSKSLPMQI 723  

                   DGEP<-*
                   DGEP   
   mKIAA0718   724 DGEP    727  

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