hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpf/mpf00289/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0711  ( 634 res)   mpf00289

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
Kelch_1  Kelch motif                                    117.5    2.5e-31   3
BTB      BTB/POZ domain                                  49.3    8.6e-11   1
Kelch_2  Kelch motif                                     47.6    2.8e-10   3

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
BTB        1/1     140   238 ..     1   135 []    49.3  8.6e-11
Kelch_1    1/3     355   406 ..     1    45 []    47.5    3e-10
Kelch_2    1/3     355   406 ..     1    54 []    10.4       11
Kelch_1    2/3     408   449 ..     1    45 []    42.5  9.4e-09
Kelch_2    2/3     408   449 ..     1    54 []    18.9     0.12
Kelch_1    3/3     453   494 ..     1    45 []    27.5  0.00031
Kelch_2    3/3     453   494 ..     1    54 []    18.4     0.17

Alignments of top-scoring domains:
BTB: domain 1 of 1, from 140 to 238: score 49.3, E = 8.6e-11
                   *->lnelreqgelcDVtLvvgdgsgrydvgkkfkAHKavLaacSpYFkal
                            +    D ++ v         g++++AHKavLaa+S+YF+a 
   mKIAA0711   140    VGSVHGEP---DLVIEVA--------GRRLRAHKAVLAARSDYFRAR 175  

                   FtgqfkesiteeessvsseieledvspedfealLefiYtgelsitqdqks
                    + +              ++  ++vs++++++lL  +Y+g+         
   mKIAA0711   176 ASRD--------------VLRVQGVSFTALRLLLADAYSGRMAGV----- 206  

                   PssckseenvedlLalAadllqipslvdkCeefliksl<-*
                        +++nv+++ a A ++lq+p++ +  +e +  +l   
   mKIAA0711   207 -----RPDNVAEVVAGA-RRLQLPGAAQRATEAMAPQL    238  

Kelch_1: domain 1 of 3, from 355 to 406: score 47.5, E = 3e-10
                   *->pRsgagvvvldgkiYviGGydg.......qslnsvevYDpetntWtk
                      p +g+g +vl ++++v+GG+ + +++++ ++++ v++Y+p+t++W+ 
   mKIAA0711   355    PARGCGLCVLFNYLFVAGGVAPagpdgraRPSDQVYCYNPVTDSWST 401  

                   lpsmp<-*
                   + +++   
   mKIAA0711   402 VRPLR    406  

Kelch_2: domain 1 of 3, from 355 to 406: score 10.4, E = 11
                   *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW
                      p  ++ ++v+ + l+v GG+  +  g+++ +  s+ +++++p t +W
   mKIAA0711   355    PARGCGLCVLFNYLFVAGGV--APAGPDGRARPSDQVYCYNPVTDSW 399  

                   eklpalp<-*
                   + + +l    
   mKIAA0711   400 STVRPLR    406  

Kelch_1: domain 2 of 3, from 408 to 449: score 42.5, E = 9.4e-09
                   *->pRsgagvvvldgkiYviGGydgqslnsvevYDpetntWtklpsmp<-
                      +Rs +   +ldg++Y++GG +   l sve+YDp+ ++Wt ++++p  
   mKIAA0711   408    ARSQVQLLALDGHLYAVGGEC---LLSVERYDPRADRWTAVAPLP   449  

                   *
                    
   mKIAA0711     -   -    

Kelch_2: domain 2 of 3, from 408 to 449: score 18.9, E = 0.12
                   *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW
                       r+++ +  ++g ly vGG              ++++ ++dp+  +W
   mKIAA0711   408    ARSQVQLLALDGHLYAVGGE------------CLLSVERYDPRADRW 442  

                   eklpalp<-*
                   + +++lp   
   mKIAA0711   443 TAVAPLP    449  

Kelch_1: domain 3 of 3, from 453 to 494: score 27.5, E = 0.00031
                   *->pRsgagvvvldgkiYviGGydgqslnsvevYDpetntWtklpsmp<-
                        + + +++++g+iYv GG+    +    +YDp+ ++W+++p  +  
   mKIAA0711   453    FAVAHEAATCNGEIYVSGGSL---FYRLLKYDPRRDEWQECPCSS   494  

                   *
                    
   mKIAA0711     -   -    

Kelch_2: domain 3 of 3, from 453 to 494: score 18.4, E = 0.17
                   *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW
                      + + h +++++g +yv+GGs            ++ +ll +dp+  +W
   mKIAA0711   453    FAVAHEAATCNGEIYVSGGS------------LFYRLLKYDPRRDEW 487  

                   eklpalp<-*
                    ++p+     
   mKIAA0711   488 QECPCSS    494  

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