hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg00550/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0705  ( 1252 res)   mbg00550

Scores for sequence family classification (score includes all domains):
Model         Description                               Score    E-value  N 
--------      -----------                               -----    ------- ---
PDZ           PDZ domain (Also known as DHR or GLGF)    220.8      2e-62   5
WW            WW domain                                  92.3      1e-23   2
Guanylate_kin Guanylate kinase                          -31.2       0.22   1

Parsed for domains:
Model         Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------      ------- ----- -----    ----- -----      -----  -------
Guanylate_kin   1/1       1    83 [.     1   107 []   -31.2     0.22
WW              1/2     149   178 ..     1    30 []    54.1  3.1e-12
WW              2/2     195   224 ..     1    30 []    42.3  1.1e-08
PDZ             1/5     271   352 ..     1    82 []    30.1  5.2e-05
PDZ             2/5     450   525 ..     1    82 []    30.4  4.3e-05
PDZ             3/5     621   704 ..     1    82 []    39.8  6.2e-08
PDZ             4/5     765   852 ..     1    82 []    63.1  6.1e-15
PDZ             5/5     985  1064 ..     1    82 []    72.8  7.1e-18

Alignments of top-scoring domains:
Guanylate_kin: domain 1 of 1, from 1 to 83: score -31.2, E = 0.22
                   *->TRpPRpgEvdGkDYhFVsSrEemekdIsaneFLEyaefnGNyYGTsk
                                   Y F++ +Ee++++ + ++ LE +++++NyYGT k
   mKIAA0705     1    -------------YIFIT-VEEFMELEKSGALLESGTYEDNYYGTPK 33   

                   eaVrqvaksGkiciLDvepQGvkqlrtaelsNPvsvFIaPpSlqelekrL
                   + ++ +   ++         + ++l  a +s +     + +S+  +ek+ 
   mKIAA0705    34 PPAEPAPLLNV---------TDQILPGATPS-AEGKRKRNKSVTNMEKAS 73   

                   rgrnketEEs<-*
                        e EE+   
   mKIAA0705    74 IEPPEEEEEE    83   

WW: domain 1 of 2, from 149 to 178: score 54.1, E = 3.1e-12
                   *->LppgWeerkdpdGrpYYyNhnTktTqWekP<-*
                      Lp +We++++++G +Y+++hnTktT+W +P   
   mKIAA0705   149    LPDNWEMAYTEKGEVYFIDHNTKTTSWLDP    178  

WW: domain 2 of 2, from 195 to 224: score 42.3, E = 1.1e-08
                   *->LppgWeerkdpdGrpYYyNhnTktTqWekP<-*
                      Lp gWe++ dp   +YY++h++++Tq+e+P   
   mKIAA0705   195    LPYGWEKIDDPIYGTYYVDHINRRTQFENP    224  

PDZ: domain 1 of 5, from 271 to 352: score 30.1, E = 5.2e-05
                   *->evtlekevkrgglGfsikggsdk...givvsevlpGsgaAeagGrLk
                      ++tl+k  ++ g+Gf+i  g+d++++ + v++v+p+ g+A+++G+ +
   mKIAA0705   271    STTLKK--SNMGFGFTI-IGGDEpdeFLQVKSVIPD-GPAAQDGKME 313  

                   eGDqIlsvNGqdvenlsheravlalkgsgg.sevtLtil<-*
                    GD+I+ +N + v +++h+++v++ ++ + + +v L++    
   mKIAA0705   314 TGDVIVYINEVCVLGHTHADVVKLFQSVPIgQSVNLVLC    352  

PDZ: domain 2 of 5, from 450 to 525: score 30.4, E = 4.3e-05
                   *->evtlekevkrgglGfsikggsdkgivvsevlpGsgaAeagGrLkeGD
                      ++t+ k  + +g+Gf+i+     g  v+ +l       + G L+eGD
   mKIAA0705   450    TLTIVK--GAQGFGFTIADSPT-GQRVKQILDI---QGCPG-LCEGD 489  

                   qIlsvNGqdvenlsheravlalkgsgg.sevtLtil<-*
                    I+++N+q+v nlsh ++v++lk+++ +se +L i    
   mKIAA0705   490 LIVEINQQNVQNLSHTEVVDILKDCPVgSETSLIIH    525  

PDZ: domain 3 of 5, from 621 to 704: score 39.8, E = 6.2e-08
                   *->evtlekevkrgglGfsikggsdk..givvsevlpGsgaAeagGrLke
                      e++++ ++  +g+Gf+i gg++ +++i +  v+++ g+A+++GrL++
   mKIAA0705   621    ELDVHLRRMESGFGFRILGGDEPgqPILIGAVIAM-GSADRDGRLHP 666  

                   GDqIlsvNGqdvenlsheravlalkgsgg.sevtLtil<-*
                   GD ++ v+G +v++ +h  +++++  +  +++v Lt++   
   mKIAA0705   667 GDELVYVDGIPVAGKTHRYVIDLMHHAARnGQVNLTVR    704  

PDZ: domain 4 of 5, from 765 to 852: score 63.1, E = 6.1e-15
                   *->evtlekevkrgglGfsikggsdk..........givvsevlpGsgaA
                      +v++++  +++g+Gf i   s ++++++ + + +  + +++ Gs+a+
   mKIAA0705   765    DVVIHRK-ENEGFGFVI-ISSLNrpesgatitvPHKIGRIIDGSPAD 809  

                   eagGrLkeGDqIlsvNGqdvenlsheravlalkgsggsevtLtil<-*
                    +++ Lk+GD+Il+vNGq++ n++h+++v+++k++g  +vtL i+   
   mKIAA0705   810 RCAK-LKVGDRILAVNGQSIINMPHADIVKLIKDAGL-SVTLRII    852  

PDZ: domain 5 of 5, from 985 to 1064: score 72.8, E = 7.1e-18
                   *->evtlekevkrgglGfsikggsdk..givvsevlpGsgaAeagGrLke
                      +v++ek  +  g+Gfsi+gg + +  ++v ++ ++ g+A + Gr ++
   mKIAA0705   985    TVDMEK--GAKGFGFSIRGGREYkmDLYVLRLAED-GPAIRNGRMRV 1028 

                   GDqIlsvNGqdvenlsheravlalkgsggsevtLtil<-*
                   GDqI+++NG+++++++h+ra++++k+ g   v+L+++   
   mKIAA0705  1029 GDQIIEINGESTRDMTHARAIELIKSGGR-RVRLLLK    1064 

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