hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mnh/mnh05261/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0691  ( 677 res)   mnh05261

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N 
--------   -----------                                  -----    ------- ---
Not3       Not1 N-terminal domain, CCR4-Not complex c   254.3    1.6e-72   1
NOT2_3_5   NOT2 / NOT3 / NOT5 family                    208.7    8.8e-59   1
Extensin_2 Extensin-like region                        -139.4       0.49   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
Not3         1/1       1   168 [.     1   272 []   254.3  1.6e-72
Extensin_2   1/1     174   582 ..     1   385 []  -139.4     0.49
NOT2_3_5     1/1     504   672 ..     1   197 []   208.7  8.8e-59

Alignments of top-scoring domains:
Not3: domain 1 of 1, from 1 to 168: score 254.3, E = 1.6e-72
                   *->makRKLQqEIDrvlKKvsEGvElFddIweKvhstdnaNQkqkhhkEK
                                                                     
   mKIAA0691     -    ----------------------------------------------- -    

                   lEaDLKKEIKKLQRlRDQIKtWlssseIKDKkvsasYedsLldnRrlIEt
                                                         ++L++nR+lIEt
   mKIAA0691     1 --------------------------------------RQLIENRKLIET 12   

                   aMErFKvVEKetKtKafSKeGLgaqeklDPkekGDDleKreardwlnnvI
                   +MErFKvVE+etKtKa+SKeGLg+++k+DP++k    eK+e+++wl+n+I
   mKIAA0691    13 QMERFKVVERETKTKAYSKEGLGLAQKVDPAQK----EKEEVGQWLTNTI 58   

                   deLnkQvDqlEaElesLSntDlGkGkRlkkkKkKtdsdrqeriedlKrki
                   d+Ln+QvDq+E+E+esLS         ++++KkK+d+d+q+rie+lKr+i
   mKIAA0691    59 DTLNMQVDQFESEVESLS---------VQTRKKKGDKDKQDRIEGLKRHI 99   

                   eRhkfHIekLEliLRlLdNdeLdpeqVnetiKDDieYYVEsnQDDfpDFe
                   e+h++H+++LE+iLR+LdNd++ ++++++ iKDD+eYYV+s+QD  pDFe
   mKIAA0691   100 EKHRYHVRMLETILRMLDNDSILVDAIRK-IKDDVEYYVDSSQD--PDFE 146  

                   EyDeiYddlevdEldEvelsesaqq<-*
                   E++++Yddl+   l++++++ +a++   
   mKIAA0691   147 ENEFLYDDLD---LEDIPQALVATS    168  

Extensin_2: domain 1 of 1, from 174 to 582: score -139.4, E = 0.49
                   *->lltlvvalvslslpseasakYsYsSPPPpekpY..............
                       +   +   s s p++++     sSP Pp++   +++++++++++++
   mKIAA0691   174    HMEDEIFNQSSSTPTSTT----SSSPIPPSPANcttenseddkkrgr 216  

                   .....vYkSPPpPspkyvykSPPPpkkpYvYsSPPPPsyvykSPPPPkpy
                   +++++v +SP       +++S   p      +SP  P + y S PPP   
   mKIAA0691   217 stdseVSQSPAK-NGSKPVHSNQHP------QSPAVP-PTYPSGPPPTTS 258  

                   vYkSPPpP.kyvYkSPPpPvykYkSPPPPthsppPpyvykSPPPPpkkyv
                     +S P  +       P+     k  P P+        ++S  P p  y 
   mKIAA0691   259 ALSSTPGNnGASTPAAPTSALGPKASPAPS--------HNSGTPAP--YA 298  

                   ykSpPpptPvYkYkSPPPPp..............................
                       Pp +       P PP+ ++++++++++++++++++++++++ ++++
   mKIAA0691   299 QAVAPPNASGPSNAQPRPPSaqpsggsgggsggsssnsnsgtgggagkqn 348  

                   ......yvYkspPpPvkk..........ripyvYkSPPPPpP..YvYkSp
                   + ++ + v   +P+ v  +++++++ +++     + P  P P++ +  S 
   mKIAA0691   349 gatsysSVVADSPAEVTLsssggssassQALGPTSGPHNPAPstSKESST 398  

                   PppvkkyiyksppppephkYvYkSPPPPpPYvyesvpeqkikYvYkSPPP
                     p+      s    +   +    P P  P                 P  
   mKIAA0691   399 AAPSGAGNVASGSGNNSGGPSLLVPLPVNP-----------------PSS 431  

                   PkksYkspsppkyVYkSpPpPvipykYkSPPPPkkkyspaPrkpyvYkSP
                   P++s+          + pP        k P P + + ++  ++  + +  
   mKIAA0691   432 PTPSFSEAKAAGTLLNGPPQFSTTPEIKAPEPLS-SLKSMAERAAISSGI 480  

                   PPPtyvYkSpPpPykpptppkiyksPPPPtPvyvYkspPpippik.....
                     P++      +      +    + PP  + ++   s   ip   +  + 
   mKIAA0691   481 EDPVPTLHLTDR----DIILSSTSAPPTSSQPPLQLSEVNIPLSLgvcpl 526  

                   .sssppPvyvYkSpPppvysPPPPyvYssPPPPvyvynsaPvykksPPkh
                   ++ s +    Y+ +             + P P          ++++ P +
   mKIAA0691   527 gPVSLTKEQLYQQAMEEA------AWHHMPHPSDSERIRQYLPRNPCPTP 570  

                   hYiYsSPPPphh<-*
                   +Y    PPP+     
   mKIAA0691   571 PYHHQMPPPHSD    582  

NOT2_3_5: domain 1 of 1, from 504 to 672: score 208.7, E = 8.8e-59
                   *->DlttlglnLnstensvtdklllttFagPwadqpakpkqqdpmE.AyY
                        t+++++L ++e + ++++l   + gP + +++ ++qq + E A+ 
   mKIAA0691   504    --TSSQPPLQLSEVN-IPLSLGVCPLGPVSLTKEQLYQQAMEEaAWH 547  

                   klPefgdekvPeeYstinpairpsltpqaQaPi..idnslilkklrvdlf
                   + P ++d+++ + Y+++np ++p+ +   Q+P+++ d+++++++     +
   mKIAA0691   548 HMPHPSDSERIRQYLPRNPCPTPPYHH--QMPPphSDTVEFYQR-----L 590  

                   sddtLFflFYympgIDdvaQllAAkELFkkRgWRyHKeervWftRhpgme
                   s++tLFf+FYy +g  + aQ+lAAk L kk++WR+H+++++Wf+Rh+  e
   mKIAA0691   591 STETLFFIFYYLEG--TKAQYLAAKAL-KKQSWRFHTKYMMWFQRHE--E 635  

                   PdknkvktdiQrEGeyErGsYeyFDpeksrelradWekirKegdFrleYe
                   P   k++td     e+E+G+Y+yFD+e +      W +++Ke +F++eY 
   mKIAA0691   636 P---KTITD-----EFEQGTYIYFDYE-K------WGQRKKE-GFTFEYR 669  

                   yLe<-*
                   yLe   
   mKIAA0691   670 YLE    672  

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