hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbh/mbh00872/w3open/interpro/cnk_1/seq.in
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query:  mKIAA0688  ( 893 res)   mbh00872

Scores for sequence family classification (score includes all domains):
Model           Description                             Score    E-value  N 
--------        -----------                             -----    ------- ---
ADAM_spacer1    ADAM-TS Spacer 1                        186.4    4.6e-52   1
TSP_1           Thrombospondin type 1 domain             39.4    8.3e-08   1
Pep_M12B_propep Reprolysin family propeptide            -10.6     0.0057   1
Reprolysin      Reprolysin (M12B) family zinc metallo   -43.6    1.8e-08   1

Parsed for domains:
Model           Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------        ------- ----- -----    ----- -----      -----  -------
Pep_M12B_propep   1/1     153   270 ..     1   119 []   -10.6   0.0057
Reprolysin        1/1     276   484 ..     1   203 []   -43.6  1.8e-08
TSP_1             1/1     580   630 ..     1    55 []    39.4  8.3e-08
ADAM_spacer1      1/1     742   859 ..     1   128 []   186.4  4.6e-52

Alignments of top-scoring domains:
Pep_M12B_propep: domain 1 of 1, from 153 to 270: score -10.6, E = 0.0057
                   *->hLeknrsllapdftvttYdedGtlvteepliqddHCyYqGyVeGypn
                       Le+  +   +++tv + +++ ++      ++    y  G++ G+p+
   mKIAA0688   153    ELEQDPGVQVEGLTVQYLGQAPEMLGGAEPGT----YLTGTINGDPE 195  

                   SaVslSTCsGgLRGilqlenlsYgIEPles....sdgf..eHiiYqienl
                   S++sl    G L G+lq  + +  ++Ple++  +s+g+++ Hi+ + +  
   mKIAA0688   196 SVASLHWDGGALLGVLQYRGAELHLQPLEGgalnSAGGpgAHIL-RRKSP 244  

                   ktepspcgecgslstsadssygirsass<-*
                   +   +p+  c ++  s ++s+++r       
   mKIAA0688   245 ASSQGPM--CTVKAPSGSPSPISRRTKR    270  

Reprolysin: domain 1 of 1, from 276 to 484: score -43.6, E = 1.8e-08
                   *->rYiELvIVvDhgmytkygsdlnkirqrVhqivNlvNeiYrpqLNIr.
                      r++E  +V+D +m   +g   +  + + + ++  + + ++    Ir+
   mKIAA0688   276    RFVETLVVADDKMAAFHG---TGLKRYLLTVMAAAAKAFKH-PSIRn 318  

                   ...VvLvgLEI........WsdgDkInvqsdandTLhsFge....WRetd
                   + + v + L I++ +++++W      +v + +       +  +++   + 
   mKIAA0688   319 pvnLVVTRLVIgparkgpkWG-----QVPPRPYAASAPGSGastpLTTQI 363  

                   LlkrksHDnAqLLtgidf....dgntiGaAyvggmCspkrSvGVvqdhsp
                   L +      A+L+t  d+ + ++  t+G+A vg++C+p rS+++v+d   
   mKIAA0688   364 LTTLT----AILFTRQDLcgvsTCDTLGMADVGTVCDPARSCAIVEDD-- 407  

                   ivllvAvtMAHELGHNLGmtHDdkntdgCtCe....gggsCIMnpvasss
                     l  A t AHELGH + m HD  +  +Ct  ++++g++  +M+pv  + 
   mKIAA0688   408 -GLQSAFTAAHELGHVFNMLHDNSK--PCTNLngqgGSSRHVMAPVMAHV 454  

                   pskKkFSnCSkddyqkFltkqkpqCLlNkP<-*
                    +    S CS     +Fl ++ ++CLl+kP   
   mKIAA0688   455 DPEEPWSPCSARFITDFLDNGYGHCLLDKP    484  

TSP_1: domain 1 of 1, from 580 to 630: score 39.4, E = 8.3e-08
                   *->spWseWSpCSVTCGkGirtRqRvcnspaPqkkggepCtgdvqelete
                      +pW++W +CS TCG+G++   R c  p+P+  gg+ C+g  ++  ++
   mKIAA0688   580    GPWGPWGDCSRTCGGGVQFSSRDCTRPVPR-NGGKYCEGRRTR--FR 623  

                   aCdmmdkC<-*
                    C + + C   
   mKIAA0688   624 SC-NTENC    630  

ADAM_spacer1: domain 1 of 1, from 742 to 859: score 186.4, E = 4.6e-52
                   *->ktvkGtFtkaslgaGYndVvtIPaGArhIlIrElkkSgqrnddnyLA
                       +++G+F+k++  +GY dVvtIPaGA+hIl+r+++ Sg ++   yLA
   mKIAA0688   742    SKQSGSFKKFR--YGYSDVVTIPAGATHILVRQQGGSGLKS--IYLA 784  

                   LknsdTGskyiLNGnwtisapgrtfelaGTv.feYsrisddvsntapEsL
                   Lk sd Gs y LNG++t++++ +++ l G+v+++Ys+ +++    a E+L
   mKIAA0688   785 LKLSD-GS-YALNGEYTLMPSPTDVVLPGAVsLRYSG-ATA----ASETL 827  

                   tatGPtnepLivqvLfqggapnpgikYeYtiP<-*
                   +++GP+ +pL++qvL+ g+ +n +++Y++++P   
   mKIAA0688   828 SGHGPLAQPLTLQVLVAGNPQNARLRYSFFVP    859  

//