hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg11644/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0641  ( 1415 res)   mbg11644

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
TyrKc    Tyrosine kinase, catalytic domain              221.7    6.3e-62   1
S_TKc    Serine/Threonine protein kinases, catalytic    112.2      6e-29   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
TyrKc      1/1     176   446 ..     1   280 []   221.7  6.3e-62
S_TKc      1/1     176   449 ..     1   231 []   112.2    6e-29

Alignments of top-scoring domains:
TyrKc: domain 1 of 1, from 176 to 446: score 221.7, E = 6.3e-62
                   *->ltlgkkLGeGaFGeVykGtlk.....ieVAVKtLkeda....keeFl
                      l  +k++G+G FG+V++G+  ++ ++++V VK Lk +a+ ++++ Fl
   mKIAA0641   176    LLYLKEIGHGWFGKVFLGEVHsgvsgTQVVVKELKVSAsvqeQMQFL 222  

                   rEakiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLld
                   +Ea+  + l  +H N++++l+ c e         P+++vmE++++GdL+ 
   mKIAA0641   223 EEAQPYRAL--QHSNLLQCLAQCAEV-------TPYLLVMEFCPLGDLKG 263  

                   yLrknrpk....lslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvg
                   yLr++r +++    + +L  +A  +A+G  +L+++n+vH DLA RNcL++
   mKIAA0641   264 YLRSCRVTesmaPDPLTLQRMACEVACGVLHLHRHNYVHSDLALRNCLLT 313  

                   enkvvKIsDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWmAPEs
                   ++++vK++D GLs   y +       dy +++   +    +P+rW APE 
   mKIAA0641   314 ADLTVKVGDYGLSHCKYRE-------DYLVTAD--QLW--VPLRWIAPEL 352  

                   l.........kdgkFtskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsne
                    ++ +++    d   t  S VWS GV++WE+f lG+qPYp       s++
   mKIAA0641   353 VdevhgnllvVDQ--TKSSNVWSLGVTIWELFELGAQPYPQ-----HSDR 395  

                   evleylkkGyRlpkPendl..piSsvtCPdelYdlMlqCWaedPedRPtF
                   +vl+y  +   l+ P+  l+        +d  Y++M+ CW   Pe+RPt 
   mKIAA0641   396 QVLAYAVREQQLKLPKPQLqlA-----LSDRWYEVMQFCWLQ-PEQRPTA 439  

                   selverl<-*
                   +e++ +l   
   mKIAA0641   440 EEVHLLL    446  

S_TKc: domain 1 of 1, from 176 to 449: score 112.2, E = 6e-29
                   *->YellkklGkGaFGkVylardkk..tgrlvAiKvik........eril
                         lk++G+G FGkV+l+  +++ +g +v +K++k + + +++ ++l
   mKIAA0641   176    LLYLKEIGHGWFGKVFLGEVHSgvSGTQVVVKELKvsasvqeqMQFL 222  

                   rEikiLkk.dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrgr
                    E +  +  +H N+ +++  + + + + lVmE+c+   GdL+ +l++++ 
   mKIAA0641   223 EEAQPYRAlQHSNLLQCLAQCAEvTPYLLVMEFCPL--GDLKGYLRSCR- 269  

                   rglrkvlsE.ea......rfyfrQilsaLeYLHsqgIiHRDLKPeNiLLd
                          +E++a+++ + +++++++++++ +LH+++ +H DL   N LL+
   mKIAA0641   270 ------VTEsMApdpltlQRMACEVACGVLHLHRHNYVHSDLALRNCLLT 313  

                   s..hvKlaDFGlArql.........ttfvGTpeYmAPEvl..........
                    + +vK++D Gl+    +++   + + + + + ++APE++++ +++    
   mKIAA0641   314 AdlTVKVGDYGLSHCKyredylvtaDQLWVPLRWIAPELVdevhgnllvv 363  

                   gYgkpavDiWSlGcilyEllt.GkpPFp...qldlifkkig.........
                     +k ++ +WSlG++++El+  G  P+p++++ +++   +++   + +++
   mKIAA0641   364 DQTK-SSNVWSLGVTIWELFElGAQPYPqhsDRQVLAYAVReqqlklpkp 412  

                   ......SpeakdLikklLvkdPekRlta.eaLedeldikaHPff<-*
                         S+   + ++ ++   Pe+R+ta+e+        +  ++   
   mKIAA0641   413 qlqlalSDRWYEVMQFCWL-QPEQRPTAeEVHL------LLSYL    449  

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