hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg11644/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0641  ( 1415 res)   mbg11644

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase_Tyr Protein tyrosine kinase                     236.7    3.3e-67   1
Pkinase     Protein kinase domain                        73.4    4.9e-18   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Pkinase       1/1     176   446 ..     1   287 []    73.4  4.9e-18
Pkinase_Tyr   1/1     176   446 ..     1   272 []   236.7  3.3e-67

Alignments of top-scoring domains:
Pkinase: domain 1 of 1, from 176 to 446: score 73.4, E = 4.9e-18
                   *->yelleklGsGsfGtVykakhkgtgk..iVAvKiikkrkekskkdkta
                      +  l+ +G G fG+V+++  ++   +++V+vK++k++      ++  
   mKIAA0641   176    LLYLKEIGHGWFGKVFLGEVHSGVSgtQVVVKELKVSASVQ--EQMQ 220  

                   rrrsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrlldLfdyl
                   ++  E+q  + L+H N ++++  + + + + lV+E+c+ G    dL+ yl
   mKIAA0641   221 FLE-EAQPYRALQHSNLLQCLAQCAEVTPYLLVMEFCPLG----DLKGYL 265  

                   setrrkgpll..f..sedeakkialQilrgleYLHsngiiHRDLKPeNIL
                   +    ++++++++ +++ +++++a ++++g+ +LH+++ +H DL + N+L
   mKIAA0641   266 R----SCRVTesMapDPLTLQRMACEVACGVLHLHRHNYVHSDLALRNCL 311  

                   ldengvvdaflKiaDFGlAkkls.t.sss.lttfvGTpwYmAPEv.....
                   l  + +v    K++D Gl+ ++++++  ++++ + + ++++APE+ ++ +
   mKIAA0641   312 LTADLTV----KVGDYGLSHCKYrEdYLVtADQLWVPLRWIAPELvdevh 357  

                   ..llggngygtkvDvWSlGvilyellt.GkpPFs.gevqdsldqlqlirk
                   ++ll   + ++++ vWSlGv+++el+  G  P+++++     d ++l + 
   mKIAA0641   358 gnLL-VVDQTKSSNVWSLGVTIWELFElGAQPYPqHS-----DRQVLAYA 401  

                   ilgpplefdspewdsisrsefrrlpnlseeakdLikkcLnkDPskRltae
                   +++ +l+ + p+  +          +ls+   +++  c+ + P++R+tae
   mKIAA0641   402 VREQQLKLPKPQLQL----------ALSDRWYEVMQFCW-LQPEQRPTAE 440  

                   eilqHPwf<-*
                   e+     +   
   mKIAA0641   441 EVHLL--L    446  

Pkinase_Tyr: domain 1 of 1, from 176 to 446: score 236.7, E = 3.3e-67
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtLkeigasseeie
                      l  +k++G+G FG+V++G+ +   +  +++V VK Lk  +as +e  
   mKIAA0641   176    LLYLKEIGHGWFGKVFLGEVH--SGVSGTQVVVKELKV-SASVQE-- 217  

                   redFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGdL
                   +  Fl+EA+  + l +H N++++l+ c +   P    +++V+E++++GdL
   mKIAA0641   218 QMQFLEEAQPYRAL-QHSNLLQCLAQCAE-VTP----YLLVMEFCPLGDL 261  

                   ldfLrkhr..egrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcL
                   + +Lr+ r +e  +++  +L  +a ++A+G  +L+++n+vH DLA RNcL
   mKIAA0641   262 KGYLRSCRvtESMAPDPLTLQRMACEVACGVLHLHRHNYVHSDLALRNCL 311  

                   VsenlvVKIsDFGLaRdiynddyYvrkkgggklPvkWmAPEslkygkF..
                   ++ +l+VK++D GL+   y +dy  ++ +   +P +W APE l + + ++
   mKIAA0641   312 LTADLTVKVGDYGLSHCKYREDYL-VTADQLWVPLRWIAPE-LVDEVHgn 359  

                   ......tskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyRL
                       ++t  S VWS GV++WE+f lG+qP Yp  s+ +vl++   + ++L
   mKIAA0641   360 llvvdqTKSSNVWSLGVTIWELFELGAQP-YPQHSDRQVLAYA-VREQQL 407  

                   prPenCP.......delYdlMlqCWaedPedRPtFselverL<-*
                   + P+  P+ +   +d  Y++M+ CW  +Pe+RPt +e++  L   
   mKIAA0641   408 KLPK--PqlqlalsDRWYEVMQFCW-LQPEQRPTAEEVHLLL    446  

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