hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg10346/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0638  ( 1386 res)   mbg10346

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N 
--------   -----------                                  -----    ------- ---
PH         PH domain                                     72.5    8.9e-18   1
FHA        FHA domain                                    47.8    2.3e-10   1
Extensin_2 Extensin-like region                        -135.3       0.34   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
FHA          1/1       1    62 [.     1    94 []    47.8  2.3e-10
Extensin_2   1/1     136   445 ..     1   385 []  -135.3     0.34
PH           1/1    1266  1379 ..     1    92 []    72.5  8.9e-18

Alignments of top-scoring domains:
FHA: domain 1 of 1, from 1 to 62: score 47.8, E = 2.3e-10
                   *->vtiGRdsdsddilldddqdislsgsiSrrHatieykdggvslelafr
                      ++iG+  ++ di+l+ +      g ++++H+ ie+  g+        
   mKIAA0638     1    TVIGS--AARDISLQGP------G-LAPEHCYIENLRGTL------- 31   

                   laqvkefgvylrDlssknlnGatfvNgkrlgngepvrLksGdvirlG<-*
                            +l+++++++      ++g ++   +p+rL++G++++lG   
   mKIAA0638    32 ---------TLYPCGNAC-----TIDGLPV--RQPTRLTQGCMLCLG    62   

Extensin_2: domain 1 of 1, from 136 to 445: score -135.3, E = 0.34
                   *->lltlvvalvslslpseasakYsYsSPPPpekpYvYkSPPpPspkyvy
                       ++  ++l     + +  a  s+ SP     +Y   SPP  sp    
   mKIAA0638   136    EIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL-SPPT-SP--GA 178  

                   kSPPPpkkpYvYsSPPPPsyvykSPPPPkpyvYkSPPpPkyvYkSPPpPv
                    S   +   Y   SP            P     +SP       +  P+  
   mKIAA0638   179 MSVGSS---YENTSPAFS---------P----LSSPASSGSCASHSPSGQ 212  

                   ykYkSPPPPthsppPpyvykSPPPPpk..kyvykSpPpptPvYkYkSPPP
                       S PP + +    y+    PP ++++    +  P+   +     PP 
   mKIAA0638   213 EPGPSVPPLVPARSSSYHLALQPPQSRpsGSRSSDSPRLGRKGGHERPPS 262  

                   Pp...yvYkspPpPvkkripyvYkSPPPPpPYvYkSpPppvkkyiykspp
                   P  ++    sp + v  + +    SP           P +    i  s  
   mKIAA0638   263 PGlrgLLTDSPAATVLAEARRTTESPRLGGQ-----LPVVA---ISLSEY 304  

                   ppephkYvYkSPPPPpPYvyesvpeqkikYvYkSPPPPkksYkspsppky
                   p +      +S P   P      p      +++SP P             
   mKIAA0638   305 PSSGA----RSQPASIP----GSP------KFQSPVPA------------ 328  

                   VYkSpPpPvipykYkSPPPPkkkyspaPrkpyvYkSPPPPtyvYkSpPpP
                        P+  i      PP P             ++ PP    v  S P  
   mKIAA0638   329 -----PRNKIGTLQDHPPSP-------------FREPPGTERVLTSSPSR 360  

                   yk.....pptppkiyksPPPPtP......vyvYkspPpippiksssppPv
                   +  +++ +   +      PP +P+ ++++    +  Pp+ p         
   mKIAA0638   361 QLvgrtfSDGLAATRTLQPPESPrlgrrgLDSMRELPPLSP--------- 401  

                   yvYkSpPppvysPPPPyvYssPPPPvyvynsaPvykksPPkhhYiYsSPP
                       S  +   sP P    +  P P     s  v  ++ P+     +  P
   mKIAA0638   402 ----SLSRRALSPLPA---RTAPDPKL---SREVAESPRPRRWAAHGTSP 441  

                   Pphh<-*
                     +    
   mKIAA0638   442 EDFS    445  

PH: domain 1 of 1, from 1266 to 1379: score 72.5, E = 8.9e-18
                   *->vikeGwLlkkg.gkkswkkRyfvLfn..dvLlyykdkk.kkpkgsip
                       +++G+L k+g+++kswkkR+fv+ + +++L+yy dk++ k+kg+i 
   mKIAA0638  1266    KVCRGYLIKMGgKIKSWKKRWFVFDRlkRTLSYYVDKHeTKLKGVIY 1312 

                   Lsgi.qvekvpdn.................krkncFeirt.dretlllqa
                    + i++v+++   +  +++  + +  +++++   +F+++t+dr  +++ a
   mKIAA0638  1313 FQAIeEVYYDHLRsaakkrffhftmvtespNPALTFCVKThDR-LYYMVA 1361 

                   eseeerkeWvkaiqsair<-*
                   +s+e ++ W++ i   ++   
   mKIAA0638  1362 PSAEAMRIWMDVIVTGAE    1379 

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