hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg01004/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0623  ( 1056 res)   mbg01004

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    325.8    2.9e-93   1
TyrKc    Tyrosine kinase, catalytic domain               89.7    3.4e-22   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
S_TKc      1/1      28   290 ..     1   231 []   325.8  2.9e-93
TyrKc      1/1      28   290 ..     1   280 []    89.7  3.4e-22

Alignments of top-scoring domains:
S_TKc: domain 1 of 1, from 28 to 290: score 325.8, E = 2.9e-93
                   *->YellkklGkGaFGkVylardkk.tgrlvAiKvik........erilr
                      Y + +++G+GaF++V+++r++ +t+ +vAiK i++++ +++++ + +
   mKIAA0623    28    YCKRDLVGHGAFAVVFRGRHRQkTDWEVAIKSINkknlsksqILLGK 74   

                   EikiLkk.dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrgrr
                   EikiLk+ +H+NIV Lydv e +++++lVmEyc+G  GdL d+l+ +g+ 
   mKIAA0623    75 EIKILKElQHENIVALYDVQELpNSVFLVMEYCNG--GDLADYLQAKGT- 121  

                   glrkvlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds......
                        lsE+++r +++Qi+ a+  LHs+gIiHRDLKP+NiLL+  +++++
   mKIAA0623   122 -----LSEdTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYanrrks 166  

                   .....hvKlaDFGlArql......ttfvGTpeYmAPEvl...gYgkpavD
                   + ++ ++K+aDFG+Ar l++++   t++G+p YmAPEv+ +++Y+  ++D
   mKIAA0623   167 nvsgiRIKIADFGFARYLhsntmaATLCGSPMYMAPEVImsqHYDA-KAD 215  

                   iWSlGcilyElltGkpPFp.....qldlifkkig..........Speakd
                    WS+G ++y +l+GkpPF+ +++++l + ++k ++  ++ ++++Sp + +
   mKIAA0623   216 LWSIGTVIYQCLVGKPPFQanspqDLRMFYEKNRslmpsipretSPYLAN 265  

                   LikklLvkdPekRlta.eaLedeldikaHPff<-*
                   L+ +lL+++ ++R+  +  +        HPf+   
   mKIAA0623   266 LLLGLLQRNQKDRMDFeAFFS-------HPFL    290  

TyrKc: domain 1 of 1, from 28 to 290: score 89.7, E = 3.4e-22
                   *->ltlgkkLGeGaFGeVykGtlk....ieVAVKtLkeda....keeFlr
                        + +  G+GaF +V++G+ +++++ eVA+K++++   ++++  + +
   mKIAA0623    28    YCKRDLVGHGAFAVVFRGRHRqktdWEVAIKSINKKNlsksQILLGK 74   

                   EakiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLldy
                   E+ki+k+l  +H+NiV+L+ v   +         +++vmEy+ gGdL dy
   mKIAA0623    75 EIKILKEL--QHENIVALYDVQELP-------NSVFLVMEYCNGGDLADY 115  

                   LrknrpklslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenk..
                   L++++  ls ++   f +QIA+ M+ L+sk+++HRDL   N+L++  +++
   mKIAA0623   116 LQAKGT-LSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANrr 164  

                   .......vvKIsDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWm
                   +++ ++ ++KI+DFG +R+l++         +  ++  ++         m
   mKIAA0623   165 ksnvsgiRIKIADFGFARYLHSN--------TMAATLCGSPM------YM 200  

                   APEslkdgkFtskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevley
                   APE+++   +  k D WS G +++  +  G++P         s+++++ +
   mKIAA0623   201 APEVIMSQHYDAKADLWSIGTVIY-QCLVGKPPFQA-----NSPQDLRMF 244  

                   lkkGyRlpkPendlpiSsvtCPdelYdlMlqCWaedPedRPtFsel..ve
                    +k + l++    +       ++ l +l l   +++ +dR  F++  ++ 
   mKIAA0623   245 YEKNRSLMPSIPRE------TSPYLANLLLGLLQRNQKDRMDFEAFfsHP 288  

                   rl<-*
                   +l   
   mKIAA0623   289 FL    290  

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