hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbf/mbf03424/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0621  ( 847 res)   mbf03424

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RhoGAP   RhoGAP domain                                  155.0    1.3e-42   1
SH3_1    SH3 domain                                      52.4    9.7e-12   1
PH       PH domain                                       47.7    2.6e-10   1
SH3_2    Variant SH3 domain                              24.8      0.002   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PH         1/1     299   402 ..     1    92 []    47.7  2.6e-10
RhoGAP     1/1     424   580 ..     1   155 []   155.0  1.3e-42
SH3_1      1/1     792   847 .]     1    58 []    52.4  9.7e-12
SH3_2      1/1     793   847 .]     1    69 []    24.8    0.002

Alignments of top-scoring domains:
PH: domain 1 of 1, from 299 to 402: score 47.7, E = 2.6e-10
                   *->vikeGwLlkkg...gkkswkkRyfvLfn....dvLlyykdkk...kk
                       ++eG+L+++++++++ sw k+y++ ++++++ +++ ++ k++++  
   mKIAA0621   299    YTMEGYLYVQEkrhFGTSWVKHYCTYQRdskqITMVPFDQKSggkGG 345  

                   pkgsipLsgiqvekvpdnkrkncFeirt.dr.etlllqaeseeerkeWvk
                      s+ L++++ +k++++++++cF +   dr+ ++++qa see+r+ W++
   mKIAA0621   346 EDESVTLKSCTRRKTDSIEKRFCFDVEAvDRpGVITMQALSEEDRRLWME 395  

                   aiqsair<-*
                   a         
   mKIAA0621   396 AMDGREP    402  

RhoGAP: domain 1 of 1, from 424 to 580: score 155.0, E = 1.3e-42
                   *->PlivekCieflekrGLdtEGIyRvsGsksrikeLreafdrgedvdl.
                        i++kCi ++e rG++++G+yR+ G  sr+++L   +   ++  ++
   mKIAA0621   424    -SIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKAASEt 469  

                   ..ndleeedvhvvAslLKlFLReLPePLltfelyeefieaaaksedeeer
                   ++    e  + +v+s+LK++LR LP PL+ +++   fi+ aak+e+ e+r
   mKIAA0621   470 etDICAEWEIKTVTSALKTYLRMLPGPLMMYQFQRSFIK-AAKLENQETR 518  

                   lealrellrkLPpaNrdtLryLlahLnrVaqnsevNkMtahNLAivFgPt
                   +++++ l++ LP+ Nr+ L+ L+ hL++Va n+++N+Mt+ NL++vFgPt
   mKIAA0621   519 VSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPT 568  

                   Llrppdgd.sad<-*
                   Llrp++++  a+   
   mKIAA0621   569 LLRPQEETvAAI    580  

SH3_1: domain 1 of 1, from 792 to 847: score 52.4, E = 9.7e-12
                   *->kkvvALYDYearesdELsFkkGDvitvleksdd.gWWkgrlkgtgGk
                      +k++ALY+ +a++++ELsF+ G v+ ++  s ++gW++g l+   Gk
   mKIAA0621   792    RKAKALYACQAEHDSELSFTAGTVFDNVHPSQEpGWLEGTLN---GK 835  

                   eGliPsNYVepv<-*
                   +GliP NYVe     
   mKIAA0621   836 TGLIPENYVEFL    847  

SH3_2: domain 1 of 1, from 793 to 847: score 24.8, E = 0.002
                   *->ygraiedyvaAtdknenleeeeLslkkGdvvkvidvggskddd....
                      +++a+  + a +  +e      Ls+++G    v+      d+ ++++
   mKIAA0621   793    KAKALYACQA-EHDSE------LSFTAGT---VF------DNVhpsq 823  

                   ..gwwlgeslggGrrrRGlvPssaveel<-*
                   ++gw +g++  +G++  Gl+P ++ve l   
   mKIAA0621   824 epGWLEGTL--NGKT--GLIPENYVEFL    847  

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