hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbh/mbh04636/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0583  ( 582 res)   mbh04636

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
GuKc     Guanylate kinase homologues.                   190.7    1.4e-52   1
PDZ      Domain present in PSD-95, Dlg, and ZO-1/2.     114.5    1.2e-29   2
SH3      Src homology 3 domains                          39.0    6.5e-07   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PDZ        1/2      19    90 ..     1    80 []    72.5  5.1e-17
PDZ        2/2     174   246 ..     1    80 []    42.2  7.1e-08
SH3        1/1     260   324 ..     1    58 []    39.0  6.5e-07
GuKc       1/1     385   571 ..     1   203 []   190.7  1.4e-52

Alignments of top-scoring domains:
PDZ: domain 1 of 2, from 19 to 90: score 72.5, E = 5.1e-17
                   *->gglGfsivg....gifvssvvpGspAakaGrkslglLkvGDvIleVN
                      ++lG+siv+++++g++vs+v  Gs A++aG      L  GD++le N
   mKIAA0583    19    EPLGISIVSgekgGVYVSKVTLGSIAHQAG------LEYGDQLLEFN 59   

                   GetsvegltheeavdllkkaggggvGekvtLtvlRgg<-*
                   G ++++++t+++a +++ + ++     ++t++ ++++   
   mKIAA0583    60 G-INLRSATEQQARLIIGQQCD-----TITILAQYNP    90   

PDZ: domain 2 of 2, from 174 to 246: score 42.2, E = 7.1e-08
                   *->gglGfsivg....gifvssvvpGspAakaGrkslglLkvGDvIleVN
                        lG+ + g++ +g+fv++v+++spA    +     L +GD Ile  
   mKIAA0583   174    LDLGVHLCGgnlhGVFVAEVEDDSPAKGPDG-----LVPGDLILEYG 215  

                   GetsvegltheeavdllkkaggggvGekvtLtvlRgg<-*
                      ++++ t e++ + + k+++     +++L+v+++    
   mKIAA0583   216 S-LDMRSRTVEDVYVEMLKPKD-----SLRLKVQYRH    246  

SH3: domain 1 of 1, from 260 to 324: score 39.0, E = 6.5e-07
                   *->eyvvAlYDyeaqnedELsFkkGDiitvleks....ddgWweGelnr.
                      +y +AlYD  a+ e ELsFkk+Di++v +  +++  + W+  +l+ +
   mKIAA0583   260    FYIRALYDRLAEVEPELSFKKDDILYVDDTLpqgvFGSWMAWQLDEn 306  

                   ..tGkeGlfPsnYVeeie<-*
                    ++ ++G +Ps YV  +e   
   mKIAA0583   307 aqKIQRGQIPSKYVMDQE    324  

GuKc: domain 1 of 1, from 385 to 571: score 190.7, E = 1.4e-52
                   *->drRpivLsGpsGvGKstlkakLlqeyPdypkfgfsVshTTRppRpgE
                      d+ ++ +++ ++v +++l+ +Ll       +++++V+ +  +  pg 
   mKIAA0583   385    DSVSLAYQRVQKVDCTSLRPVLLLG-----PLLDVVKEMLVNEAPGK 426  

                   vnGPvvDYhFvsLkeefeqdiksgkflEwgeysgnlyYGTskesvrqvae
                   ++ ++ +++ +s ++++e+++k+++f++++  sg+ + +T+++s+++++e
   mKIAA0583   427 FCRCPLEVMKAS-QQAIERGVKDCLFVDYKRRSGH-FDVTTVASIKEITE 474  

                   kGKhclLDidpqgvkqlkkarRkselnpiviFIapPsleeleerlrgaeq
                   k++hclLDi+p+++++l+++    +++piviFI+++s+++++e++  + +
   mKIAA0583   475 KNRHCLLDIAPHAIERLHHM----HIYPIVIFIRYKSAKHIKEQRD-PVY 519  

                   RgteteeriqkrlaaaaqkeaqeyskeahlFdlvivnddledayYkeLke
                     ++ ++r++k++++ aqk+ qeys   ++F++v+++  l++++ +++++
   mKIAA0583   520 LRDKVTQRHSKEQFETAQKIDQEYS---RYFTGVVQGGALSSIC-TQILA 565  

                   ileaeq<-*
                   ++ +eq   
   mKIAA0583   566 MVSQEQ    571  

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