hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbh/mbh04636/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0583  ( 582 res)   mbh04636

Scores for sequence family classification (score includes all domains):
Model         Description                               Score    E-value  N 
--------      -----------                               -----    ------- ---
PDZ           PDZ domain (Also known as DHR or GLGF)     87.8    2.2e-22   2
SH3_2         Variant SH3 domain                         16.2       0.11   1
SH3_1         SH3 domain                                  6.0       0.04   1
Guanylate_kin Guanylate kinase                           -6.1     0.0019   1

Parsed for domains:
Model         Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------      ------- ----- -----    ----- -----      -----  -------
PDZ             1/2      11    87 ..     1    82 []    61.4  1.9e-14
PDZ             2/2     165   243 ..     1    82 []    27.2  0.00038
SH3_1           1/1     260   323 ..     1    58 []     6.0     0.04
SH3_2           1/1     261   323 ..     1    69 []    16.2     0.11
Guanylate_kin   1/1     438   532 ..     1   107 []    -6.1   0.0019

Alignments of top-scoring domains:
PDZ: domain 1 of 2, from 11 to 87: score 61.4, E = 1.9e-14
                   *->evtlekevkrgglGfsikggsdkgivvsevlpGsgaAeagGrLkeGD
                       v+++k  + ++lG+si++g+++g++vs+v  G + A+++G L+ GD
   mKIAA0583    11    HVKVQK--GSEPLGISIVSGEKGGVYVSKVTLG-SIAHQAG-LEYGD 53   

                   qIlsvNGqdvenlsheravlalkgsggsevtLtil<-*
                   q+l+ NG ++++ ++ +a+l++ +  + ++t++ +   
   mKIAA0583    54 QLLEFNGINLRSATEQQARLIIGQQCD-TITILAQ    87   

PDZ: domain 2 of 2, from 165 to 243: score 27.2, E = 0.00038
                   *->evtlekevkrgglGfsikggsdkgivvsevlpGsgaAeagGrLkeGD
                       +++ k  ++  lG+ + gg+ +g++v+ev  +s+a   +G L +GD
   mKIAA0583   165    RIVFIKK-SQLDLGVHLCGGNLHGVFVAEVEDDSPAKGPDG-LVPGD 209  

                   qIlsvNGqdvenlsheravlalkgsggsevtLtil<-*
                    Il+ +  d+++ ++e++  ++ ++++ +++L+++   
   mKIAA0583   210 LILEYGSLDMRSRTVEDVYVEMLKPKD-SLRLKVQ    243  

SH3_1: domain 1 of 1, from 260 to 323: score 6.0, E = 0.04
                   *->kkvvALYDYearesdELsFkkGDvitvleksdd....gWWkgrlkgt
                       + +ALYD  a+ + ELsFkk D+++v +  + +  + W   +l+  
   mKIAA0583   260    FYIRALYDRLAEVEPELSFKKDDILYVDDTLPQgvfgSWMAWQLDE- 305  

                   gG....keGliPsNYVepv<-*
                    + ++ ++G iPs YV +    
   mKIAA0583   306 -NaqkiQRGQIPSKYVMDQ    323  

SH3_2: domain 1 of 1, from 261 to 323: score 16.2, E = 0.11
                   *->ygraiedyvaAtdknenleeeeLslkkGdvvkvidvggskddd...g
                      y+ra+ d  a + ++e      Ls+kk+d+++v     ++ + +  g
   mKIAA0583   261    YIRALYDRLA-EVEPE------LSFKKDDILYVD----DTLPQgvfG 296  

                   wwlg.eslggGrr.r.RGlvPssaveel<-*
                   +w +  + +++  + +RG +Ps++v  +   
   mKIAA0583   297 SWMAwQL-DENAQkIqRGQIPSKYVMDQ    323  

Guanylate_kin: domain 1 of 1, from 438 to 532: score -6.1, E = 0.0019
                   *->TRpPRpgEvdGkDYhFVsSrEemekdIsaneFLEyaefnGNyYGTsk
                                       s   ++e++ +  +F  y   +G+   T++
   mKIAA0583   438    -----------------S-QQAIERGVKDCLFVDYKRRSGHFDVTTV 466  

                   eaVrqvaksGkiciLDvepQGvkqlrtaelsNPvsvFIaPpSlqelek..
                   ++++++ +++++c+LD+ p ++ +l   + + P+++FI+ +S +  ++++
   mKIAA0583   467 ASIKEITEKNRHCLLDIAPHAIERLHHMHIY-PIVIFIRYKSAKHIKEqr 515  

                   .....rLrgrnketEEs<-*
                   ++   r++  ++ + E+   
   mKIAA0583   516 dpvylRDKVTQRHSKEQ    532  

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