hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj02119/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0573  ( 436 res)   mfj02119

Scores for sequence family classification (score includes all domains):
Model         Description                               Score    E-value  N 
--------      -----------                               -----    ------- ---
Thioredoxin   Thioredoxin                                63.6    4.2e-15   1
HyaE          Hydrogenase-1 expression protein HyaE     -31.4        0.1   1
Calsequestrin Calsequestrin                             -73.2     0.0042   1

Parsed for domains:
Model         Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------      ------- ----- -----    ----- -----      -----  -------
HyaE            1/1      49   153 ..     1   114 []   -31.4      0.1
Thioredoxin     1/1      60   171 ..     1   114 []    63.6  4.2e-15
Calsequestrin   1/1      38   397 ..     1   386 []   -73.2   0.0042

Alignments of top-scoring domains:
HyaE: domain 1 of 1, from 49 to 153: score -31.4, E = 0.1
                   *->LiqRLlt..rfGwpvVDNaatlDdflaaAdeepgdgVLLlaGDPaRf
                      L+    t+ +++ + +D   ++D+ l+     ++ +++ +  D  Rf
   mKIAA0573    49    LVTSIFTpiTAEIASLD-SENIDEILNN----ADVALVNFYADWCRF 90   

                   P........EalDvAVVLPELlraFpqrfrgavvarDreqEeaLaaRFgv
                    +  ++  +Ea+Dv      +  + p+    + ++ D  q + +a+R+++
   mKIAA0573    91 SqmlhpifeEASDV------IKEEYPDKNQVVFARVDCDQHSDIAQRYRI 134  

                   lrrPsLvffrdGrylGvLagirDWdEY<-*
                   +++P+L  fr G             EY   
   mKIAA0573   135 SKYPTLKLFRNGMMMK--------REY    153  

Thioredoxin: domain 1 of 1, from 60 to 171: score 63.6, E = 4.2e-15
                   *->vvvvltdenFdeevlkaksdkpVLVdFyApWCGpCKmlAPeyeklAq
                      ++  l  en de +++    +  LV FyA+WC   +ml P++e++++
   mKIAA0573    60    EIASLDSENIDEILNN---ADVALVNFYADWCRFSQMLHPIFEEASD 103  

                   eykges..d.dvkfaKVDaDenpkdlAskygVrgfPTlkffknGkk.epv
                     k+e +++++v+fa VD+D++  d+A++y ++ +PTlk+f+nG   +  
   mKIAA0573   104 VIKEEYpdKnQVVFARVDCDQHS-DIAQRYRISKYPTLKLFRNGMMmK-R 151  

                   dyvgGArtkddLvafikkhlg<-*
                   +y g  r+  +L+++i+++ +   
   mKIAA0573   152 EYRGQ-RSVKALADYIRQQKS    171  

Calsequestrin: domain 1 of 1, from 38 to 397: score -73.2, E = 0.0042
                   *->krphLvlAaLlLlvsgtpklGvrgeeGLdFPeYDGkDRvislseKny
                        + L+  +LlL+ s      +   e            + sl   n 
   mKIAA0573    38    SLADLRCSLLLLVTS---IFTPITAE------------IASLDSENI 69   

                   KqvlKKYev.LaLlYHEpvedDKasqrqFeleEliLELaAqvLEdK....
                    ++l   +v L  +Y +         r  ++   i E a  v+ +  +++
   mKIAA0573    70 DEILNNADVaLVNFYADWC-------RFSQMLHPIFEEASDVIKEEypdk 112  

                   .gvGFglvDsekdAavAKKLGldEedslYvlKgDevi..EyDGEFsADtl
                   ++v F+ vD ++   +A++  +     l  +++  ++++Ey G  s   l
   mKIAA0573   113 nQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMkrEYRGQRSVKAL 162  

                   vEFLLDvlEDPvEliegkrElqAFEnieDeiKLiGyFKsedsEhYKAfEd
                    +++      Pv  i++  E+   ++   +i  iGyF  +dsE Y+ fE 
   mKIAA0573   163 ADYIRQQKSNPVHEIQSLDEVTNLDRSKRNI--IGYFEQKDSENYRVFER 210  

                   AAEeFhPYikFFAtFDkkvAKkLtLKlnEiDfYEpFmdEPitiPdKPnsE
                    A   h    F   F     K        + +  p    P  +     + 
   mKIAA0573   211 VASILHDDCAFLSAF-GDLSKPERYNGDNVIYKPPGRSAPDMVYLGSMTN 259  

                   eEiv.eFvkeHkRptLRkLrPesmyEtWEDDlnGiHivAFAEesDPDGyE
                    ++  +++++   p +R +  e+  E  E+ l    ++ F  ++D +  E
   mKIAA0573   260 FDVTyNWIQDKCVPLVREITFENGEELTEEGLP--FLILFHMKDDTESLE 307  

                   FLeilKevArDnt.dnPDLsiiWiDPdDF..PLLvpYWEktFkiDLskPq
                     +   evAr   ++   +  +  D d F++PLL        +i      
   mKIAA0573   308 IFQ--NEVARQLIsEKGTINFLHADCDKFrhPLL--------HIQKTPAD 347  

                   iGvvnvtDADsvWmeidDeeDLPtaeELEDWiEDvLeGeintEDDDdddd
                     v+ +     +++   D  D+     L  ++ D  +G++  E     d 
   mKIAA0573   348 CPVIAIDSFRHMYV-FGDFKDVLIPGKLKQFVFDLHSGKLHREFHHGPDP 396  

                   D<-*
                       
   mKIAA0573   397 T    397  

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