hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpm/mpm09246/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0564  ( 1246 res)   mpm09246

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
AAA_5    ATPase family associated with various cellul   162.7    6.4e-45   1
VWA      von Willebrand factor type A domain             -7.8      0.055   1
AAA_3    ATPase family associated with various cellul   -22.6       0.63   1
DUF444   Protein of unknown function (DUF444)          -228.1       0.65   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
AAA_3      1/1     116   250 ..     1   133 []   -22.6     0.63
AAA_5      1/1     116   271 ..     1   184 []   162.7  6.4e-45
DUF444     1/1     821  1175 ..     1   457 []  -228.1     0.65
VWA        1/1    1058  1237 ..     1   195 []    -7.8    0.055

Alignments of top-scoring domains:
AAA_3: domain 1 of 1, from 116 to 250: score -22.6, E = 0.63
                   *->HvLlegvPGlaKTllvkalAkaldlkfkRiQaFTpD.......LlPs
                      H+Ll g  G++K ++v  + ++l+   + iQ +  D++ ++ +L P+
   mKIAA0564   116    HLLLVGNQGVGKNKIVDRFLHLLNRPREYIQ-LHRDttvqsltLQPT 161  

                   DilGtevydektrefefkkGPvFanllLADEINRappKtQsALLEaMeEl
                      G  vy+++     +k G    ++l  DE   ap  +   +L  + E 
   mKIAA0564   162 VKGGLIVYEDSPLVKAVKLG----HILVVDEADKAPTNV-TCILKTLVEN 206  

                   rqVTvdgethkLpepFlVlATqNPieqeGtY.pLPEAqlDRFll<-*
                    +  +++ ++ + +   V   +N +  +  ++ L  A    F +   
   mKIAA0564   207 GEMILADGRRIVADAANVDGRENLVAIHPDFrMLALANRPGFPF    250  

AAA_5: domain 1 of 1, from 116 to 271: score 162.7, E = 6.4e-45
                   *->pvlLvGppGtGKtelaerLaaalsgqggrpvfyvqltrdtteedllg
                      ++lLvG++G+GK+ +++r++++l    +rp++y+ql+rdtt + l+ 
   mKIAA0564   116    HLLLVGNQGVGKNKIVDRFLHLL----NRPREYIQLHRDTTVQSLTL 158  

                   rrniaplleGngttswvdgpLvrAaryaretegslpeghilvlDEinras
                   +  ++     +g  +++d+pLv+A++           ghilv+DE ++a+
   mKIAA0564   159 QPTVK-----GGLIVYEDSPLVKAVK----------LGHILVVDEADKAP 193  

                   pevlnvLlslLderrlllpdggelvkvppydklaerg.reeldlwklgrl
                    +v+++L +l +++++ l dg+++v+++++     +++re+       ++
   mKIAA0564   194 TNVTCILKTLVENGEMILADGRRIVADAAN-----VDgREN-------LV 231  

                   .ihd.frlIatsNpldgprglnelsaALrrRFlfvtvdpp<-*
                    ih++fr++a++N++++p+ +n+ +  L++ F ++++d+p   
   mKIAA0564   232 aIHPdFRMLALANRPGFPFLGNDFFGTLGDIFSCHAIDNP    271  

DUF444: domain 1 of 1, from 821 to 1175: score -228.1, E = 0.65
                   *->MgiFiDrrlNgtlkdKs......tvnRQRflrrvkYeaIKkslpDaV
                       +   D      + dKs+  + +++ R R+ +    e + +sl +  
   mKIAA0564   821    ISAISDTDALLAEWDKSsvvtvdMGGRVRLWETGL-ERLQQSLMEW- 865  

                   sePesIidldsgevvkIPi.....rgldEpkfhyGkqgGkrkhVgpGndD
                      ++ i+ ds + v+I i+++++++++ pk +  +  ++  hVg Gn  
   mKIAA0564   866 ---RNMIGQDSDKHVQITIerdsnEDVSDPKHGKED-PDNMPHVG-GNT- 909  

                   EAGDefqkGDvIardqggggaegsGkGqaagdgeGKKV..VAETe.DdFe
                          +G   +rd  g g    GkG+     +G  V +V E e+D+  
   mKIAA0564   910 ------WAGGTGGRDTAGLG----GKGGPYRLDAGHPVyqVSEVEkDAVP 949  

                   fevsre..EvldllFeDLeLPNLkkkeadqiveDfkterAgRiqksGvpa
                   + v r  +E     F     + Lk  + ++ +  ++ ++   +q +    
   mKIAA0564   950 EDVKRAarEMAQKAFQ----QRLKEIQMSEYDAATYERFSSAVQRQVHAL 995  

                   nInvkRtlrsaikRrialerakraeldalaeelariarsepidLmeeavd
                   +I     +     R +++  a   eld+             + +++    
   mKIAA0564   996 RIILDNLQAKGKERQWLRHQA-TGELDD-------------AKIIDG--- 1028 

                   rlreeiaeLrakieRVPFidteDLRfkrykkvpkpesnAVvfclMDVSGS
                            +a+ +++   ++ DL      ++ kp +   v+   DVSGS
   mKIAA0564  1029 ---------LAGEKSIY-KRRGDLEPQLGSPQQKPKRLRLVV---DVSGS 1065 

                   MdeseKdlAkRFFflLylFLtrkYenvEivFIrHhTeAkEVdEedFFykq
                   M +         F   ++ L r  e v  v      eA E  Ee F    
   mKIAA0564  1066 MYR---------FNGVDRRLERSMEAVCMV-----MEAFENYEEKF---- 1097 

                   EsGGTivSSALklaeeiidERYppaeWNIYafqaSDGDNftdDserCvkl
                                       +Y+ a       + +DG N        + +
   mKIAA0564  1098 --------------------KYDIAG------HSGDGYNIK------LVP 1115 

                   LrkklmelaqyyaYvEitDGVqrrsHstGatenGtsLWrkyeavkgvkDn
                   ++ ++ ++     ++  t      +Hs           +   +  + ++ 
   mKIAA0564  1116 VN-QIPKNNKQRLEILKT----MHEHSQ--------FCMSGDHTLEGTEH 1152 

                   kFamqtIrekdDiypVfrelFqkeea<-*
                     +  + +e +D y V+  +++  +    
   mKIAA0564  1153 -AIKDITTEEADEYFVI--ILSDANL    1175 

VWA: domain 1 of 1, from 1058 to 1237: score -7.8, E = 0.055
                   *->DivFllDgSgSigeen....lFekvkdFvkklveknldigpdgtrVg
                         +++D+SgS+ + n+ ++++e+  ++v  ++e +++ ++++  + 
   mKIAA0564  1058    ---LVVDVSGSMYRFNgvdrRLERSMEAVCMVME-AFENYEEKFKYD 1100 

                   lvqYssdvr..tefsLndy.sskddllaav...lknlrylgGgTnNtgkA
                   +   s+d ++   ++ n+ +++ +++l+ +++    +++   g + t ++
   mKIAA0564  1101 IAGHSGDGYniKLVPVNQIpKNNKQRLEILktmHEHSQFCMSGDH-TLEG 1149 

                   LkyalenlfsstMikrnrsagsRpenapkvlillTDGksndggdve.aaa
                    ++a++ ++++            +     ++i+l+D + +  g ++ + a
   mKIAA0564  1150 TEHAIKDITTE------------E-ADEYFVIILSDANLSRYGINPaRFA 1186 

                   alrdkkkgvgitvfavGvG..gdvdeaeLr.iasepeseghvfyvedfda
                   ++  +  +  ++ fa+ +G+ gd      r++       g+ f+  d ++
   mKIAA0564  1187 QILTS--DPQVNAFAIFIGslGDQAARLQRtLP--A---GRSFIAMDTKK 1229 

                   lwlelqdiqeql<-*
                     ++  +i +q+   
   mKIAA0564  1230 --IP--QILQQI    1237 

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