hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj60347/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0547  ( 703 res)   mfj60347

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
LCM      Leucine carboxyl methyltransferase             481.5   6.7e-141   1
Kelch_2  Kelch motif                                     29.8    6.1e-05   4
Omt_N    O-methyltransferase N-terminus                 -14.3      0.056   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Omt_N      1/1      31   115 ..     1   121 []   -14.3    0.056
LCM        1/1      28   330 ..     1   330 []   481.5 6.7e-141
Kelch_2    1/4     434   483 ..     1    54 []     0.8    2e+02
Kelch_2    2/4     497   545 ..     1    54 []    13.8      3.8
Kelch_2    3/4     550   598 ..     1    54 []    10.0       12
Kelch_2    4/4     602   647 ..     1    54 []     7.4       27

Alignments of top-scoring domains:
Omt_N: domain 1 of 1, from 31 to 115: score -14.3, E = 0.056
                   *->aRtalDtWDlassVGaTAlmVAaaRAletrrpdpLirDpfAeplvra
                      + t++      ss        +  R l+++     +rDpfA++l   
   mKIAA0547    31    QSTND------SS-------SLSKRSLAAHG---YVRDPFAALL--- 58   

                   aglDfftRlasgielktediddpselrgrlqrmadllAvRTrffDdyfla
                   ++ +          ++++++ +     +   r ++ ++vR  f++  +  
   mKIAA0547    59 VPGP----------VRRTPLIHRGYYVR--ARAVR-HCVR-AFLE--LTS 92   

                   AlraaGirQVVIhLgAGLDtRAYR<-*
                   Al  +  r+ ++ Lg+G D+  +R   
   mKIAA0547    93 AL-PSRTRAQILSLGSGSDSLYFR    115  

LCM: domain 1 of 1, from 28 to 330: score 481.5, E = 6.7e-141
                   *->rsVqrTndDaslSKAkckrfavrkgyvkDpyikfFvpkkvdkskaRr
                      + Vq Tnd++s    ++kr++++ gyv Dp+++++vp+       Rr
   mKIAA0547    28    GTVQSTNDSSS----LSKRSLAAHGYVRDPFAALLVPG-----PVRR 65   

                   aPeINRGYyaRtvaIrhavrkFLeqttqdgPqAALkaQIVNLGaGfDtLf
                    P+I+RGYy+R++a+rh+vr+FLe t  ++     +aQI++LG G+D+L+
   mKIAA0547    66 TPLIHRGYYVRARAVRHCVRAFLELT--SALPSRTRAQILSLGSGSDSLY 113  

                   FRLlssgeYiqSqqYldrvkfiEvDFpevverKiehIlkesellsiilge
                   FRL+ +g        l+r++++EvDFp+v ++K+++I++++el   + ++
   mKIAA0547   114 FRLKAAGL-------LARAAVWEVDFPDVSRLKAKRIEETPELR--AQTG 154  

                   skeeDyvvalsgtdLhsgsYhliGcDLRdlneleekLekcqlldanlPTi
                   ++ ++  + +s ++++s++Y ++G+DLR l++l e+L  ++ lda +PT+
   mKIAA0547   155 PFKIG--DSASSLCFESADYRILGADLRELQRLGEALHGAG-LDATSPTL 201  

                   fiAECvLvYMepeeSasLikwiaskFenalfvnYEQirpsqPnDrFGkvM
                   ++AE+vL+Y+ep ++++Li+w+a++F++alfv+YEQ++p   +D+FG++M
   mKIAA0547   202 LLAEAVLTYLEPSSATALIAWAAQRFPDALFVIYEQMQP---GDAFGQIM 248  

                   laNLkeSrgspLhGLetYesiEsQrsRFlkaGweeVivvDMneiynsflp
                   l+++ + + spLhGLe ++++ +Qr+RFl+aGw++++++D ne+y ++l+
   mKIAA0547   249 LQHFQR-LHSPLHGLELFPDVKAQRQRFLQAGWTACSALDLNEFYRRLLS 297  

                   eaEkkRiesiEpLDElEElqllcqHYcLvhAss<-*
                   ++E++R+e +Ep+DE EE++l+c HY++++As+   
   mKIAA0547   298 AEERQRVETLEPFDEYEEWHLKCSHYFILAASR    330  

Kelch_2: domain 1 of 4, from 434 to 483: score 0.8, E = 2e+02
                   *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW
                      ++y++ +++++ +++v GG+   +++++  + +++dl  ++ ++n+ 
   mKIAA0547   434    RLYHTMTRLSDTRVLVLGGR--LSPVSPASGALQLDL--YKSKDNCS 476  

                   eklpalp<-*
                   e  ++     
   mKIAA0547   477 EGQNVTV    483  

Kelch_2: domain 2 of 4, from 497 to 545: score 13.8, E = 3.8
                   *->pryphasvvp..ggklyvvGGsfkgnrgtgngdesssdllvldpetn
                      +r++++ v ++++  l+v+GG+           +++sd ++l+ et 
   mKIAA0547   497    WRHSTTEVYYqnQRYLFVYGGR-------SVAEPVLSDCRFLHVETM 536  

                   vWeklpalp<-*
                   +W ++p+ +   
   mKIAA0547   537 AWVRIPVQG    545  

Kelch_2: domain 3 of 4, from 550 to 598: score 10.0, E = 12
                   *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW
                      +r++h++++++g  ++ GG      g+ + ++ss  +l +  +   W
   mKIAA0547   550    GRHSHSACSWQGGALIAGGL-----GASEEPLSSVLFLKPVSSGFLW 591  

                   eklpalp<-*
                   e +   p   
   mKIAA0547   592 ESIDIQP    598  

Kelch_2: domain 4 of 4, from 602 to 647: score 7.4, E = 27
                   *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW
                      pry+h++ v +gkl++vGG+        + ++++ + +++ +   + 
   mKIAA0547   602    PRYSHTAHVFNGKLLLVGGV------WIHSSSVPGVTVICLTTGLSS 642  

                   eklpalp<-*
                   e+  +++   
   mKIAA0547   643 EY--QID    647  

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